Name : cagA
Accession : AAF17598.1
PAI name : cag PAI
PAI accession : AF202973
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : CagA
Function : -
Note : -
Homologs in the searched genomes : 46 hits ( 45 protein-level, 1 DNA-level )
Publication :
-Asahi,M., Azuma,T., Ito,S., Ito,Y., Suto,H., Nagai,Y., Tsubokawa,M., Tohyama,Y., Maeda,S., Omata,M., Suzuki,T. and Sasakawa,C., "Helicobacter pylori CagA protein can be tyrosine phosphorylated in gastric epithelial cells", J. Exp. Med. 191 (4), 593-602 (2000) PUBMED 10684851.
-Ito,Y. and Azuma,T., "Direct Submission", Submitted (09-NOV-1999) Second Department of Internal Medicine, Fukui Medical University, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan.
| DNA sequence : | |
ATGACTAACGAAACTATTGACCAACAACCACAAACCGAAGCGGCTTTTAACCCGCAGCAATTTATCAACAATCTTCAAGT
GGCTTTTCTTAAAGTTGATAACGCTGTCGCTTCATACGATCCTGATCAAAAACCAATCGTTGATAAGAATGATAGGGATA
ACAGGCAAGCTTTTGATGGAATCTCGCAATTAAGGGAAGAATACTCCAATAAAGCGATCAAAAATCCTACCAAAAAGAAT
CAGTATTTTTCAGACTTTATCAATAAGAGCAATGATTTAATCAACAAAGACAATCTCATTGATATAGGTTCTTCCATAAA
AAGCTTTCAGAAATTTGGGACTCAGCGTTACCGAATTTTCACAAGTTGGGTGTCCCATCAAAACGATCCGTCTAAAATCA
ACACCCGATCGATCCGAAATTTTATGGAAAATATCATACAACCCCCTATCCCTGATGACAAAGAAAAAGCAGAGTTTTTG
AAATCTGCCAAACAATCTTTTGCAGGAATCATTATAGGGAATCAAATCCGAACGGATCAAAAGTTCATGGGCGTGTTTGA
TGAATTCTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGAGCCTACTGGTGGGGATTGGTTGGATATTTTTTTATCAT
TTGTATTTAACAAAGAACAATCTTCTGATGTCAAAGAAGCAATCAATCAAGAACCAGTTCCCCATGTCCAACCAGATATA
GCCACTACCACCACCCACATACAAGGCTTACCGCCTGAATCTAGGGATTTGCTTGATGAAAGGGGTAATTTTTCTAAATT
CACTCTTGGCGATATGGAAATGTTAGATGTTGAGGGCGTCGCCGACATTGATCCTAATTACAAGTTCAATCAATTATTGA
TTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATAATGGCATAGAACCTGAAAAAGTTTCATTATTGTATGCG
GGCAATGGTGGTTTTGGAGCCAAGCACGATTGGAACGCCACCGTTGGTTATAAAAACCAACAAGGCGACAATGTGGCTAC
ACTCATTAATGTGCATATGAAAAACGGCAGTGGCTTAGTCATAGCAGGTGGTGAGAAAGGGATTAACAACCCTAGTTTTT
ATCTCTACAAAGAAGACCAACTCACAGGCTCACAACGAGCATTGAGTCAAGAAGAGATCCGAAACAAAATAGATTTCATG
GAATTTCTTGCACAAAACAATGCTAAATTAGACAACTTGAGCGAGAAAGAGAAAGAAAAATTCCAAAATGAGATTGAAGA
TTTTCAAAAAGACTCTAAGGCTTATTTAGACGCCCTAGGGAATGATCGTATTGCCTTTGTTTCTAAAAAAGACCCAAAAC
ATTCAGCTTTAATTACTGAGTTTGGTAAGGGGGATTTGAGCTACACTCTCAAAGATTATGGGAAAAAAGCAGATAGAGCT
TTAGATAGGGAGAAAAATGTTACTCTTCAAGGTAACCTAAAACATGATAGCGTGATGTTTGTTAATTATTCTAATTTCAA
ATACACCAACGCCTCCAAGAGTCCTGATAAGGGTGTAGGCGTTACAAATGGCGTTTCCCATTTAGACGCAGGCTTTAGCA
AGGTAGCTGTCTTTAATTTGCCTGATTTAAATAATCTCGCTATCACTAGTTTCGTAAGGCGGAATTTAGAGAATAAACTA
GTCACTGAAGGATTGTCCCTACAAGAAGCTAATAAGCTTATCAAAGATTTTTTGAGCAGCAACAAAGAATTGGTTGGAAA
AGCTTTAAACTTCAATAAAGCTGTAGCTGACGCTAAAAACACAGGCAACTATGATGAAGTGAAAAAAGCTCAGAAAGATC
TTGAAAAATCTCTAAGGAAACGAGAGCATTTAGAGAAAGAAGTAGAGAAAAAATTGGAGAGCAAAAGCGGCAACAAAAAT
AAAATGGAAGCGAAAGCTCAAGCTAACAGCCAAAAAGATAAGATTTTTGCGTTGATCAATAAAGAGGCTAATAGGGACGC
AAGAGCAATCGCTTACTCTCAGAATCTTAAAGGCATCAAAAGGGAATTGTCTGATAAACTTGAAAAAATCAACAAGGATT
TGAAAGACTTTAGTAAATCTTTTGATGAATTCAAAAATGGCAAAAATAAGGATTTTAGCAAGGCAGAAGAAACGCTAAAA
GCCCTTAAAGGCTCGGTGAAAGATTTAGGTATCAATCCGGAATGGATTTCAAAAGTTGAAAACCTTAATGCAGCTTTGAA
TGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACGCAAGCAAAAAGCGACCTTGAAAATTCCGTTAAAGATG
TGATCATCAATCAAAAGATAACGGATAAAGTTGACAATCTCAATCAAGCGGTATCAATGGCTAAAGCAACGGGTGATTTC
AGTAGGGTAGAGCAAGCGTTAGCCGATCTCAAAAACTTCTCAAAGGAGCAATTGGCTCAACAAACTCAAAAAAATGAAAG
TTTCAATGTTGGAAAAAAATCTGAAATATATCAATCCGTTAAGAATGGTGTGAACGGAACCCTAGTCGGTAATGGGTTAT
CTGGAATAGAGGCCACAGCTCTCGCCAAAAATTTTTCGGATATCAAGAAAGAATTGAATGAGAAATTTAAAAATTTCAAT
AACAATAACAATAATGGACTCGAAAACGAACCCATTTATGCTAAAGTTAATAAAAAGAAAACAGGACAAGTAGCTAGCCC
TGAAGAACCCATTTACGCTCAAGTTGCTAAAAAGGTGAATGCAAAAATTGACCGACTCAATCAAGCAGCAAGTGGTTTGG
GTGGTGTAGGGCAAGCGGGCTTCCCTTTGAAAAGGCATGATAAAGTTGATGATCTCAGTAAGGTAGGGCGATCAGTTAGC
CCTGAACCCATTTATGCTACGATTGATGATCTCGGCGGACCTTTCCCTTTGAAAAGGCATGATAAAGTTGATGATCTCAG
TAAGGTAGGGCGATCAGTTAGCCCTGAACCCATTTATGCTACGATTGATGATCTCGGCGGACCTTTCCCTTTGAAAAGGC
ATGATAAAGTTGATGATCTCAGTAAGGTAGGGCGATCAGTTAGCCCTGAACCCATTTATGCTACGATTGATGATCTCGGC
GGACCTTTCCCTTTGAAAAGGCATGATAAAGTTGATGATCTCAGTAAGGTAGGGCTTTCAAGGAATCAAGAATTGGCTCA
GAAAATTGACAATCTCAGTCAAGCGGTATCAGAAGCTAAAGCAGGTTTTTTTAGCAATCTAGAGCAAACGATAGACAAGC
TCAAAGATTCTACAAAATACAATTCTGTGAATCTATGGGTTGAAAGTGCAAAAAAAGTGCCTGCTAGTTTGTCAGCGAAA
CTAGACAATTACGCTACTAACAGCCACACACGCATTAATAGCAATATCCAAAATGGAGCAATCAATGAAAAAGCGACCGG
TATGCTAACGCAAAAAAACCCTGAGTGGCTCAAGCTCGTGAATGATAAGATAGTTGCGCATAATGTGGGAAGCGTTCCTT
TGTCAGAGTATGATAAAATTGGCTTCAACCAGAAGAATATGAAAGATTATTCTGATTCGTTCAAGTTTTCCACCAAGTTG
AACAATGCTGTAAAAGACGTTAAGTCTAGCTTTACGCAATTTTTAGCCAATGCATTTTCTACAGGATATTACTCCTTGGC
GAGGGAAAATGCGGAGCATGGAATCAAAAATGTTAATACAAAAGGTGGTTTCCAAAAATCTTAA
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| Protein sequence : | |
MTNETIDQQPQTEAAFNPQQFINNLQVAFLKVDNAVASYDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKN
QYFSDFINKSNDLINKDNLIDIGSSIKSFQKFGTQRYRIFTSWVSHQNDPSKINTRSIRNFMENIIQPPIPDDKEKAEFL
KSAKQSFAGIIIGNQIRTDQKFMGVFDEFLKERQEAEKNGEPTGGDWLDIFLSFVFNKEQSSDVKEAINQEPVPHVQPDI
ATTTTHIQGLPPESRDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKVSLLYA
GNGGFGAKHDWNATVGYKNQQGDNVATLINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIRNKIDFM
EFLAQNNAKLDNLSEKEKEKFQNEIEDFQKDSKAYLDALGNDRIAFVSKKDPKHSALITEFGKGDLSYTLKDYGKKADRA
LDREKNVTLQGNLKHDSVMFVNYSNFKYTNASKSPDKGVGVTNGVSHLDAGFSKVAVFNLPDLNNLAITSFVRRNLENKL
VTEGLSLQEANKLIKDFLSSNKELVGKALNFNKAVADAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKN
KMEAKAQANSQKDKIFALINKEANRDARAIAYSQNLKGIKRELSDKLEKINKDLKDFSKSFDEFKNGKNKDFSKAEETLK
ALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVIINQKITDKVDNLNQAVSMAKATGDF
SRVEQALADLKNFSKEQLAQQTQKNESFNVGKKSEIYQSVKNGVNGTLVGNGLSGIEATALAKNFSDIKKELNEKFKNFN
NNNNNGLENEPIYAKVNKKKTGQVASPEEPIYAQVAKKVNAKIDRLNQAASGLGGVGQAGFPLKRHDKVDDLSKVGRSVS
PEPIYATIDDLGGPFPLKRHDKVDDLSKVGRSVSPEPIYATIDDLGGPFPLKRHDKVDDLSKVGRSVSPEPIYATIDDLG
GPFPLKRHDKVDDLSKVGLSRNQELAQKIDNLSQAVSEAKAGFFSNLEQTIDKLKDSTKYNSVNLWVESAKKVPASLSAK
LDNYATNSHTRINSNIQNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNMKDYSDSFKFSTKL
NNAVKDVKSSFTQFLANAFSTGYYSLARENAEHGIKNVNTKGGFQKS
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