PAI Gene Information


Name : topB
Accession : AAF14809.1
PAI name : SPI-7
PAI accession : AF000001
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Not determined
Product : topoisomerase B
Function : -
Note : -
Homologs in the searched genomes :   246 hits    ( 246 protein-level )  
Publication :
    -Zhang,X.-L., Morris,C. and Hackett,J., "Salmonella typhi pilR, pilS, pilT and pilU genes", Unpublished.

    -Zhang,X.-L., Morris,C. and Hackett,J., "Direct Submission", Submitted (17-APR-1997) Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.

    -Zhang,X.-L., Morris,C. and Hackett,J., "Direct Submission", Submitted (15-JUL-1997) Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.

    -Zhang,X.-L., Morris,C. and Hackett,J., "Direct Submission", Submitted (09-NOV-1999) Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China REMARK Sequence update by submitter.

    -Zhang,X.-L., Morris,C. and Hackett,J., "Direct Submission", Submitted (03-DEC-1999) Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China REMARK Sequence update by submitter.

    -Zhang,X.-L., Morris,C. and Hackett,J., "Direct Submission", Submitted (17-FEB-2000) Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China REMARK Sequence update by submitter.

    -Zhang,X.-L., Morris,C. and Hackett,J., "Direct Submission", Submitted (22-MAR-2000) Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China REMARK Sequence update by submitter.

    -Zhang,X.L., Morris,C. and Hackett,J., "Molecular cloning, nucleotide sequence, and function of a site-specific recombinase encoded in the major 'pathogenicity island' of Salmonella typhi", Gene 202 (1-2), 139-146 (1997) PUBMED 9427557.

    -Zhang,X.L., Tsui,I.S., Yip,C.M., Fung,A.W., Wong,D.K., Dai,X., Yang,Y., Hackett,J. and Morris,C., "Salmonella enterica serovar typhi uses type IVB pili to enter human intestinal epithelial cells", Infect. Immun. 68 (6), 3067-3073 (2000) PUBMED 10816445.


DNA sequence : 
ATGCGTCTGGTGTTGTGTGAAAAACCTTCTCAGGGCAGAGATATTGCGAAGTTTCTTGGCGCCACTCAAAGAGGCGAAGG
ATTCCTGAATGGTCCGGGAGTTACAGTCACCTGGGCTCGCGGCCATCTGCTGGAGACAGCTGAACCGGAAGTATATGGCG
AACAGTATGGTAAGCCATGGCGCACCGATGTGCTTCCTTTATTACCACAGCAGTGGAAACTGGTAGTCAAAGCGGATGCA
AAAGCCCAATTCGCGGTAATTAACCGTCTGCTTAAACAGGTAGATGAGGTGGTAATTGCCACGGATGCTGACCGGGAAGG
TGAAGTAATCGCCCGTGAGTTGCTGGATTACTGCAAGTTTCAGGGGCGTGTATTCCGGTTGTGGATGTCAGCTCTGGATG
ATGCCAGTATCCGGTCAGCGTTAGCTGATTTGTGGCCGTCTTCCCGAACTGAATCGCTTTATTATGCTGGCGTGGGCAGG
AGCAGGGCTGACTGGCTGATCGGTATGAATCTGACTCGCCTGTTTACACTCCTGGGGCGTGAAGCGGGTATCGGTAACGT
ACTTTCAGTTGGCCGGGTACAAACGCCAACGCTGGCGATAGTGGTAAAGCGTGATCGTGAAATTGATAACTTCGTGTCGA
AACCGTACTTCGAAGTTATTGCCACGATGGCCGTGAATGGCGTGTTGTTTCCATCCAAATGGGTACCGGCTGCACAGTAT
TGCGATGAAGAGAAGCGTTGTATCCAGTCGGGGGTAGCGGCACAGGTGGTTCAGTTGTGTCGGCAAACGCCAACGGCTGC
GATAATCAATTGCCAGATCGAGAGGAAAAAACAATCAGCGCCGCTGGCTTTCAGCCTGAGCACACTACAACAGGCCTGCT
CCCGACACTGGGGGATGCCAGCCCAGACGGTACTTGATATCGCCCAGAAGTTATATGAAACCCACAAACTGACGACCTAT
CCCAGAACTGACTGTGGTTATCTGCCGTTATCGATGCGAGAAGAAATCCCACAGGTACTGTCTGCTGTGGTCGGAACTGA
TCCGGCGCTACAGCCGGTGGTCGCGAGTCTGGACACTCAGTTTGTGTCACGTATCTGGAATGATAAAAAAATTACCGCTC
ATCACGGTATCATTCCGACAAAACATACTGGTGATCTGAGCAAACTCAGTGATGCTGAGCGCAATGTCTATCAGCTGGTC
AGGTTGCACTACCTGGCCCAGTTCCTGCCCCAGATGGAAATTGACGTGACTGAGGCCACATTTAATATTGGCGGTCAGCT
TTTCCGTACCCGTGGTAACGTTTTGGTGAAACCCGGCTGGAAATCTCTGTTTGGCAAAATGTCCGAAGATGATGAGGATA
ATACTGGTGAAACCACACTGCCCGCCATGCAGGCGGGCCAGGTCTGCCAGGTGCAGGGCGCTGAGCAGAAGGTACTGCAG
ACAAAACCGCCTGCTCCGTACAACGATGGAACTCTTATTGCCGCGATGACCAATGCGGCGGCGTTCGTTACTGACGCCGC
GCTGAAAAAGGTGCTCAAAGAGAATGCGGGGATAGGAACTGAAGCAACACGGGCCGGGATAATCGACACGCTGTTGAAGC
GTGGGTTTCTGGTGCGTGAGAAAAAGACGCTTAAGTCAACACCTCTTGGACGTAACCTGGTGGATGTGTTGCCAGGAACG
TTAACGAATCCCGGACTTACGGCACTGTGGGAACAGATGCTGGATGAGGTAGCTGCAGGCAGGGTGAGCCTGGATGACTT
TATGGCAAAGCAAAGTCAGTGGGTCAGTCAGCTGGTCGCTCAGGGGAGATCACAGCCACTGACTATGCAGGCGCCACCTT
CACCACCCTGTCCTGTATGTGGCGGCAAGACGTTGCAGCGCAATGGAAAGAGTGGCTTGTTCTGGGGCTGCCTGAAATAT
CCGGAGTGCAAAGGTATCGTGAACAATGGTAACAAGGGCCCCAGAGGACGCAGACGAAAACCTTCGCCAGCCTAG

Protein sequence : 
MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLLETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADA
KAQFAVINRLLKQVDEVVIATDADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGR
SRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFEVIATMAVNGVLFPSKWVPAAQY
CDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERKKQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTY
PRTDCGYLPLSMREEIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDAERNVYQLV
RLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSEDDEDNTGETTLPAMQAGQVCQVQGAEQKVLQ
TKPPAPYNDGTLIAAMTNAAAFVTDAALKKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGT
LTNPGLTALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKTLQRNGKSGLFWGCLKY
PECKGIVNNGNKGPRGRRRKPSPA