PAI Gene Information


Name : shiA
Accession : AAD44731.1
PAI name : SHI-2
PAI accession : AF141323
Strain : Shigella flexneri 2002017
Virulence or Resistance: Virulence
Product : ShiA
Function : -
Note : similar to quinone reductases
Homologs in the searched genomes :   31 hits    ( 31 protein-level )  
Publication :
    -Moss,J.E., Cardozo,T.J., Zychlinsky,A. and Groisman,E.A., "The selC-associated SHI-2 pathogenicity island of Shigella flexneri", Mol. Microbiol. 33 (1), 74-83 (1999) PUBMED 10411725.

    -Moss,J.E., Groisman,E.A. and Zychlinsky,A., "Direct Submission", Submitted (07-APR-1999) Microbiology, NYU Medical Center, 540 First Avenue, New York, NY 10016, USA.


DNA sequence :
ATGAACGATAGATTATGCTTTGAAGTGCACGATAACAAGGGTTATTTCGTATTTCCGGATACCTGGTTTGGCCCATTGCT
GGGGGAGTTTGAAGAAGTGCTTGATGCATACGACGCTGATGAAATCAGCGAGACGAGTTACATCAACAAACTCCGACGCC
TTGCTCAACGGGAGCCGGACTTTATTGATATACACGCTCATCTGGCATATGCATTTCTGGAACAGAATGCCCCGCGTAAG
GCACTGAACGCCGCTCTTAAAGGACTGGCGGCAGGTAATCGTATCATCCCGGAAAGTTTCTGTGGTGAAATAATCTGGAT
GCATCCCGAAAACCGGCCTTATCTGCGCGCGCTTTATGCAGCAATTCTCGCAAATGTGCACTTACAGCGCCATCAGGATG
CGGTTATGCTCACTGATAAAATACTGGCATACAATCCTGAAGATAATCAGGGGGCTCGCTGGTTGTTGGGTTCAGAGCTG
TTACGCACCGGCGATCATGAGCGAGCCTTCAGTGTACTGAAAGAGCATGCTGATGAATTTTCACCTTACTGGTATGAACT
CGGTCTCCTGCATTTTCTGAACGGGGAACATGTTAAGGCCGCCACAGCTTTTCGCCATGGCTTTGCCACAAACACTTACA
TCGCAGAAATGCTGTGCGGAAATCTGCATCCATTTCCACTTGCTGTGTGGCATGACTTCTCCGGCTCTCTGGATACGGCA
GAAGATTACTATGCAACATACTCACCATTATGGGGACAATATCCGGAAGCATTGCTGTTTGTAAACTGGCTCTATAACCA
TTCCTCCGTGCTGCATGAACGATCAGAAATCATTAAATGCGCCGAAATGCTGATTCAGGAAGATGATTTCGAAATATGCG
AAAGTATTTTAAGACAGCAGGAGCACCTGTGGAAAAGAATTGACAAGACACTTTCTGAGGAAATTGTACAGAAATGCAGA
AATATGAACGGTGAATATATCTGGCCCTGGATATTGCCCTTTTCCGCAGCAGGGATGAAACATTCAAGCATCCAGTATCA
GTAG

Protein sequence :
MNDRLCFEVHDNKGYFVFPDTWFGPLLGEFEEVLDAYDADEISETSYINKLRRLAQREPDFIDIHAHLAYAFLEQNAPRK
ALNAALKGLAAGNRIIPESFCGEIIWMHPENRPYLRALYAAILANVHLQRHQDAVMLTDKILAYNPEDNQGARWLLGSEL
LRTGDHERAFSVLKEHADEFSPYWYELGLLHFLNGEHVKAATAFRHGFATNTYIAEMLCGNLHPFPLAVWHDFSGSLDTA
EDYYATYSPLWGQYPEALLFVNWLYNHSSVLHERSEIIKCAEMLIQEDDFEICESILRQQEHLWKRIDKTLSEEIVQKCR
NMNGEYIWPWILPFSAAGMKHSSIQYQ