PAI Gene Information


Name : unnamed
Accession : AAC12277.1
PAI name : VPI
PAI accession : AF034434
Strain : Vibrio cholerae IEC224
Virulence or Resistance: Not determined
Product : putative zinc metalloprotease
Function : -
Note : hypothetical Orf4
Homologs in the searched genomes :   7 hits    ( 7 protein-level )  
Publication :
    -Karaolis,D.K., Johnson,J.A., Bailey,C.C., Boedeker,E.C., Kaper,J.B. and Reeves,P.R., "A Vibrio cholerae pathogenicity island associated with epidemic and pandemic strains", Proc. Natl. Acad. Sci. U.S.A. 95 (6), 3134-3139 (1998) PUBMED 9501228.

    -Karaolis,D.K.R., Johnson,J.A., Bailey,C.C., Boedeker,E.C., Kaper,J.B. and Reeves,P.R., "Direct Submission", Submitted (14-NOV-1997) Center for Vaccine Development, University of Maryland School of Medicine, 685 W. Baltimore Street, Room 480 HSF, Baltimore, MD 21201, USA.


DNA sequence :
ATGAGAAAATCGATATTGATTAGCTTGTGCCTTTTTTCTAGCATTACAAATGCCTGTCCAATTGGTGATATTCTAGAGTC
TATGGAATTACCATTAGAAATTGAAACATCCCATGAGTTGCGCGCAGAATTGGCTAAGCTAACTGGTGGAACTTATTATA
GAGATTATTTATATCGATTGATTGATGAATTAAACCCATTTTTTAAAACTGACCAGATGCTAACAGCAGAGCATACCTAC
TGGGCAAAACAATTGCTTGATTTTGGAAAGCTTAAAAATTTTACAAGTGCACTTAGTTATGTGAAAATAAACAGAAACTC
TATGATACCAGAGTTTGAAGGTAGATATCTTGTTGCAAAAGAACTCTCAAAATTAGACCCAGCGCTTTTAAAATCAGGAT
GGAATACGGTTCATGAAATAAAGCTTGTAGTAACACATGATAATGTCACTACTTATTGGGAACATTTAAAAGGACAGCCT
GTTCGCGGACATGAAGCTGGCATAACGTGGGATTCTATTCCAGGAGCAGGATCACCAGAAGGTTTAACAGAATTAGTGAT
TGCTCTTCAAAAAAATCCGGATGGTAAATGGGCTATACCAACAGGTAATCATGGTTCGAAAAATCTAGTTATTCATGAGT
TTGGTCATACTCTAGATCGTGTAGTGGGTACATATTTTACTGGTAAGCCCTACAGTCAAAATCCGAGTTTTTATCAAGCT
TGGCATAGTGATTATCAACTAGGGAAGATAAAAGAACACTACTTCTTACAACCTGAGAATAACTATGCTGTTGCATTAGA
GGAGTCATTTGCTGAAGGGTTATCGAAACTTTATGGGATTGATAATATACAATCTACTTATGACTGGCCCTATATGTCCG
CTTATTTCTATGACCAGTTTAAAAAATCAATACAAGAACAAAATCAGGGTTATAAGTAA

Protein sequence :
MRKSILISLCLFSSITNACPIGDILESMELPLEIETSHELRAELAKLTGGTYYRDYLYRLIDELNPFFKTDQMLTAEHTY
WAKQLLDFGKLKNFTSALSYVKINRNSMIPEFEGRYLVAKELSKLDPALLKSGWNTVHEIKLVVTHDNVTTYWEHLKGQP
VRGHEAGITWDSIPGAGSPEGLTELVIALQKNPDGKWAIPTGNHGSKNLVIHEFGHTLDRVVGTYFTGKPYSQNPSFYQA
WHSDYQLGKIKEHYFLQPENNYAVALEESFAEGLSKLYGIDNIQSTYDWPYMSAYFYDQFKKSIQEQNQGYK