PAI Gene Information


Name : hly
Accession : AAA69525.1
PAI name : LIPI-1
PAI accession : U25443
Strain : Listeria monocytogenes 07PF0776
Virulence or Resistance: Virulence
Product : listeriolysin O
Function : -
Note : -
Homologs in the searched genomes :   149 hits    ( 149 protein-level )  
Publication :
    -Swaminathan,B., "Direct Submission", Submitted (21-APR-1995) Bala Swaminathan, Centers for Disease Control and Prevention, MSC07, 1-B341, 1600 Clifton Rd., Atlanta, GA 30333, USA.

    -Vines,A. and Swaminathan,B., "Identification and characterization of nucleotide sequence differences in three virulence-associated genes of listeria monocytogenes strains representing clinically important serotypes", Curr. Microbiol. 36 (5), 309-318 (1998) PUBMED 9541569.


DNA sequence :
ATGAAAAAAATAATGCTAGTTTTTATTACACTTATATTAGTTAGTCTACCAATTGCGCAACAAACTGAAGCAAAGGATGC
ATCTGCATTCAATAAAGAAAATTTAATTTCATCCATAGCACCACCAGCATCTCCGCCTGCAAGTCCTAAGACGCCAATCG
AAAAGAAACACGCGGATGAAATCGATAAGTATATACAAGGATTGGATTACAATAAAAACAATGTATTAGTATACCACGGA
GATGCAGTGACAAATGTGCCGCCAAGAAAAGGTTATAAAGATGGAAATGAATATATCGTTGTGGAGAAAAAGAAGAAATC
CATCAATCAAAATAATGCAGATATCCAAGTTGTGAATGCAATTTCGAGCCTAACATATCCAGGTGCTCTCGTGAAAGCGA
ATTCGGAATTAGTAGAAAATCAACCCGATGTTCTTCCTGTCAAACGTGATTCATTAACACTTAGCATTGATTTGCCAGGA
ATGACTAATCAAGACAATAAAATTGTTGTAAAAAATGCTACTAAATCGAACGTTAACAACGCAGTAAATACATTAGTGGA
AAGATGGAATGAAAAATATGCTCAAGCTTATCCAAATGTAAGTGCAAAAATTGATTATGATGACGAAATGGCTTACAGTG
AATCACAATTAATTGCAAAATTTGGTACGGCATTTAAAGCTGTAAATAATAGCTTGAATGTAAACTTCGGCGCAATCAGT
GAAGGGAAAATGCAAGAAGAAGTCATTAGTTTTAAACAAATTTACTATAACGTGAATGTTAATGAACCTACAAGACCTTC
CAGATTTTTCGGCAAAGCTGTTACTAAAGAGCAGTTGCAAGCGCTTGGAGTGAATGCAGAAAATCCTCCTGCATATATCT
CAAGTGTGGCATATGGCCGTCAAGTTTATTTGAAATTATCAACTAATTCCCATAGTACCAAAGTAAAAGCTGCTTTTGAC
GCTGCCGTAAGTGGGAAATCTGTCTCAGGTGATGTAGAACTGACAAATATCATCAAAAATTCTTCCTTCAAAGCCGTAAT
TTACGGTGGCTCCGCAAAAGATGAAGTTCAAATCATCGACGGTAACCTCGGAGACTTACGAGATATTTTGAAAAAAGGTG
CTACTTTTAACCGGGAAACACCAGGAGTTCCCATTGCCTATACAACAAACTTCTTAAAAGACAATGAATTAGCTGTTATT
AAAAACAACTCAGAATATATTGAAACAACTTCAAAAGCTTATACAGATGGAAAAATCAACATCGATCACTCTGGAGGATA
CGTTGCTCAATTCAACATCTCTTGGGATGAAATAAATTATGATCCTGAAGGTAACGAAATTGTTCAACATAAAAACTGGA
GCGAAAACAATAAAAGTAAGCTAGCTCATTTCACATCGTCCATCTATTTGCCAGGTAACGCAAGAAATATTAATGTTTAC
GCTAAAGAATGCACTGGTTTAGCTTGGGAATGGTGGAGAACGGTAATTGATGACCGGAACCTACCGCTTGTGAAAAATAG
AAATATCTCCATCTGGGGCACTACACTTTATCCGAAATATAGTAATAGTGTAGATAATCCAATCGAATAA

Protein sequence :
MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENLISSIAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHG
DAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPG
MTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAIS
EGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFD
AAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVI
KNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEINYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVY
AKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNSVDNPIE