Gene Information

Name : hsdR (SA957_0056)
Accession : YP_008584154.1
Strain : Staphylococcus aureus SA957
Genome accession: NC_022442
Putative virulence/resistance : Unknown
Product : type I restriction-modification system endonuclease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 62720 - 65839 bp
Length : 3120 bp
Strand : -
Note : -

DNA sequence :
ATGAACTTTCAATTTAATGAAGATGATTTAGAACAAGTCGCATTAGAATGGCTACAATCACTAGGCTATGACTATAAAAA
AGGTAATGAGATTAGTATGACAAGTCTAACACCAGAACGTAAAAGTGATAAAGATGTTGTCCTTCATGAACGTTTAGAGA
AAGCATTAAGAAAAATCAACTCAGATATCCATCCTCGTTTTATTGAAAAAGCGCTACATGAACTAACTTTAGAGAAGTCG
CCCAATCTTTTAGAAAATAACCTTACCTTTCATGAAAATTTGATTAATGGTATTGAAATCGAAGACTATGATGATGAAGG
ACAATCGATTGTAGAAATTGTTAAAATTATTGATTTTGAATATCCACAAAACAATGATTTTTTAGCAGTCAATCAATTAA
CTATCGTTAATGGAGACTATAAAAAACGTCCCGATATTGTACTCTTTATCAATGGCTTGCCTATCGTAGTGATTGAACTT
AAAAATTCAACAAATGAAACCGTGGGCGTCGAAGACGGTTATCATCAATTAGAAACGTATAAGATGCGTATTCCACAATT
ATTTACGTTTAACGAAGTGCTTGTTACAAGTGATGGTATTAATACAAAGGCTGGCTCTCTAACCGCAAATTATGATCGGT
TTATGACTTGGCGCAGTAAAGATGGTCAAACTGAATCATCACCAGGTTTAGCTAGCTTAGACGTACTCATTCATGGCATG
TTAAATCCAGAAACATTACTTGATTTAATTCGATATTTTGTTTTATTTCAAGATGATGGCAAAGGACATATCAGTAAAAT
TCTAGCAGCGTATCATCAATATTATGCCGTTAATAAAGCCGTTGACAGAGCTTTATTAGCTTCATCTGAGCAAGGTGATG
GTAAAGGCGGCGTTATTTGGCATACCCAAGGGTCCGGTAAAAGTTTAACCATGGTCTTTTTCTCTGGAAAATTAATTCAA
ATGCTGAATAACCCTACCTTAGTCGTCGTAACGGATCGTAATGATTTAGATAACCAACTGTACAGTACGTTTGTTAAATC
AAAAGGACGTTCTGGTAAAGGATTATTAAGACAAACACCAAAACAAGCTGAAACACGTAAAGAATTAAAATCATTATTAT
CTGTTGAGTCGGGTGGTATTGTATTTACAACGATGCAAAAATTTGAACCTGAACAAAACGAAACGACCATGGCTGCCCTA
ACAGAACGAAAAAATGTGATTGTCATGGCAGACGAAGCTCATCGTACACAATATGGCTTTAACGCAAAATACGATGATAA
AGGTGAAGGCATTAAATATGGTTATGCCAAATATTTAAGAGATGCTTTACCGAATGCAACATTCGTAGGATTTACAGGCA
CACCCGTAGCTTCAACGGATAAAAATACGCAAATGGTTTTCGGAAACTATATCGATGTTTATGATATGACACAAGCCGTC
GCTGATGGAAGCACCGTTAAAATTTACTATGAAAGTCGTGTAATTCCATTAAATCTACCTCAAAGTTTAGATTTAGATGA
AGCGTATAATGACATTACTGAAGATCAAGAAGAGGATGTAAAACAGCGTTTAAAATCAAAATGGTCCCGTATTGAAGCTT
TAGCAGGCGCAAAACCTCGTGTAGAAGCCCTAGCCAAAGATATCATCCAACACTTTGAAACACGTCAACAAGCGATGAAA
GGCAAAGGAATGATTGTAACGATGAGTCGTCGAATTGCTGTTGATTTATATGATGAAATCATTCGTCTAAAACCAGAATG
GCATTCAGATGATGATGATAAAGGAGTCATTAAAGTGGTAATGACAGGCTCATCTAGTGACCCAACTTCTTTCCAAAGAC
ACATTGGTCCTAAAAAACGCCGTAATTTATTAGAAAAACGTATGAAAGATGTGGATGATGAGTTACAACTCGTGATTGTT
CGAGATATGTGGCTGACAGGGTTTGATGTTCCTTCTATGCATACGATGTATATTGATAAACCGATGAAAGGGCATAATTT
GATGCAAGCAATTGCTCGAGTTAATCGAGTGTTTAAAGATAAGCCGGGTGGTTTAATTGTCGATTATGTGGGGATTGCCG
AAAGTTTAAAAGAGGCACTTAAAGAATATACAGAATCTGATCAAGCTCAAACGGCAATAGATACGGATAAAGCGGTTGAA
TTGATGTTATTGAAGTATGATGTAATTCAAGATATGTTATATAATCTTGATTACTCTAAATTTAATTCAGATAAAAAATC
TGAACGTTATTATACAATATCGAATACGATGGATTATGTAATTGGTTTAGGTGAAGATGAACGTCAACGTTTTATTAAAA
CAGTCACAGAATTAGGGAAAGCCTTTGCTCTTTGTGCGACTGAACCTACAGCCCAAGAACTCAACGATGAGATTGCCTTC
TTTAAAGCAGTTAAAGCAGGACTTGTTAAATTGTTACAACCGCCAAAAGAAGGAAAAACACGTAAAACACCTGCAGAAGT
TGAAGCAGAGATTAATCAACTTGTGTCACAATCTGTTGTGACTGAAGATGTCATTGATGTTTATCAAACGCTAGGTCTTG
AACAACCCGATTTATCAATCTTATCTGATGACTTTTTAAAAGATGTCGAAGGATTGAAACAGAAAAATGTGGCGGTAGAA
TTATTAAATCGATTACTCAAAGGACAAGTTAAATCATTAATGAAAACGAATGCAACGGTATCTAAGCGTTTCTCTGAGAT
GTTAGGAAATTCGATTAATAAATATAATAGTCGTTCCATTGAAACATCTAAAGTGATTGAAGAACTTATTCAACTCGCTA
AAGATATTAAACAAGAACAACAACGAGGAAATGAATTAGGCCTGAATTCAGATGAGATTGCGTTTTACGATGCTTTAGCT
TCACATGAAACAGCAAAAGAAGCCATGGGAGATAAAGAACTACGTGCGATTGCTCATGAGCTAACTAAAACAGTGAAAGA
AAACATGGGTGTTGATTGGTCTAAACGTGATAGCGCAAAAGCTAAAATGCGCGTAGCTGTTAGACGATTGCTTAAAAAAT
ATGGCTATCCACCAGATTTACAAAAAATGGCTGTAGAGCAGGTTGTAGAGCAAGCAGAACTTATGGCGAATAATCAATAA

Protein sequence :
MNFQFNEDDLEQVALEWLQSLGYDYKKGNEISMTSLTPERKSDKDVVLHERLEKALRKINSDIHPRFIEKALHELTLEKS
PNLLENNLTFHENLINGIEIEDYDDEGQSIVEIVKIIDFEYPQNNDFLAVNQLTIVNGDYKKRPDIVLFINGLPIVVIEL
KNSTNETVGVEDGYHQLETYKMRIPQLFTFNEVLVTSDGINTKAGSLTANYDRFMTWRSKDGQTESSPGLASLDVLIHGM
LNPETLLDLIRYFVLFQDDGKGHISKILAAYHQYYAVNKAVDRALLASSEQGDGKGGVIWHTQGSGKSLTMVFFSGKLIQ
MLNNPTLVVVTDRNDLDNQLYSTFVKSKGRSGKGLLRQTPKQAETRKELKSLLSVESGGIVFTTMQKFEPEQNETTMAAL
TERKNVIVMADEAHRTQYGFNAKYDDKGEGIKYGYAKYLRDALPNATFVGFTGTPVASTDKNTQMVFGNYIDVYDMTQAV
ADGSTVKIYYESRVIPLNLPQSLDLDEAYNDITEDQEEDVKQRLKSKWSRIEALAGAKPRVEALAKDIIQHFETRQQAMK
GKGMIVTMSRRIAVDLYDEIIRLKPEWHSDDDDKGVIKVVMTGSSSDPTSFQRHIGPKKRRNLLEKRMKDVDDELQLVIV
RDMWLTGFDVPSMHTMYIDKPMKGHNLMQAIARVNRVFKDKPGGLIVDYVGIAESLKEALKEYTESDQAQTAIDTDKAVE
LMLLKYDVIQDMLYNLDYSKFNSDKKSERYYTISNTMDYVIGLGEDERQRFIKTVTELGKAFALCATEPTAQELNDEIAF
FKAVKAGLVKLLQPPKEGKTRKTPAEVEAEINQLVSQSVVTEDVIDVYQTLGLEQPDLSILSDDFLKDVEGLKQKNVAVE
LLNRLLKGQVKSLMKTNATVSKRFSEMLGNSINKYNSRSIETSKVIEELIQLAKDIKQEQQRGNELGLNSDEIAFYDALA
SHETAKEAMGDKELRAIAHELTKTVKENMGVDWSKRDSAKAKMRVAVRRLLKKYGYPPDLQKMAVEQVVEQAELMANNQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 100
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 98
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 97
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 46