Gene Information

Name : pyk (SA957_1641)
Accession : YP_008585736.1
Strain : Staphylococcus aureus SA957
Genome accession: NC_022442
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1775035 - 1776792 bp
Length : 1758 bp
Strand : -
Note : -

DNA sequence : 
ATGAGAAAAACTAAAATTGTATGTACAATTGGACCAGCTTCAGAATCAGAAGAAATGATTGAGAAATTAATCAATGCTGG
TATGAACGTTGCACGATTAAACTTTTCACATGGTAGTCATGAAGAGCATAAAGGTAGAATTGATACAATTCGTAAAGTAG
CTAAAAGATTAGACAAAATTGTAGCAATTTTATTAGATACGAAAGGTCCAGAAATTCGTACGCATAATATGAAAGACGGT
ATCATTGAACTTGAACGTGGTAACGAAGTTATTGTTAGCATGAATGAAGTTGAAGGAACACCTGAAAAGTTCTCAGTAAC
ATATGAAAACTTAATTAACGATGTTCAAGTAGGTTCATACATTTTACTTGATGATGGCTTAATTGAATTACAAGTTAAAG
ATATTGATCATGCTAAAAAAGAAGTTAAATGTGATATTTTAAACTCTGGTGAGCTTAAAAACAAAAAAGGTGTTAACTTA
CCTGGTGTAAGAGTAAGTTTACCTGGTATTACAGAAAAAGATGCTGAAGATATCCGTTTCGGTATTAAAGAAAATGTTGA
CTTCATTGCAGCAAGTTTCGTACGTCGTCCTAGTGATGTTTTAGAAATTCGTGAAATTTTAGAAGAACAAAAAGCTAACA
TTTCAGTATTCCCTAAAATTGAAAACCAAGAAGGTATTGATAATATTGCGGAAATTCTTGAAGTGTCTGATGGTTTAATG
GTTGCACGTGGTGACATGGGTGTTGAAATTCCACCTGAAAAAGTACCAATGGTTCAAAAAGATTTAATCAGACAATGTAA
CAAATTAGGTAAACCAGTTATTACAGCTACACAAATGTTAGATTCTATGCAACGTAACCCACGTGCTACACGTGCAGAAG
CTAGTGACGTTGCCAACGCAATCTATGATGGTACAGATGCAGTAATGTTATCTGGTGAAACTGCTGCTGGTTTATATCCT
GAAGAAGCTGTTAAAACAATGAGAAATATTGCTGTATCAGCTGAAGCAGCCCAAGATTACAAAAAGTTATTGTCAGATCG
TACTAAATTAGTTGAAACTTCATTAGTGAATGCTATCGGTATTTCGGTTGCACATACAGCTTTAAACTTAAATGTTAAAG
CAATTGTAGCTGCTACTGAAAGTGGTTCAACGGCACGTACTATCTCTAAATATCGTCCGCATTCAGACATTATTGCAGTG
ACTCCAAGTGAAGAAACTGCACGTCAATGTTCAATTGTTTGGGGAGTTCAACCTGTAGTTAAAAAAGGACGTAAGAGTAC
AGATGCATTGTTAAACAATGCAGTTGCAACAGCTGTTGAAACTGGTAGAGTAACTAATGGTGATTTAATCATTATTACTG
CTGGTGTACCAACTGGTGAAACTGGAACTACTAATATGATGAAAATTCACCTAGTTGGTGACGAAATTGCTAATGGTCAA
GGTATTGGACGTGGATCAGTTGTTGGTACTACGTTAGTTGCTGAAACTGTTAAAGATTTAGAAGGTAAAGATTTATCTGA
CAAAGTTATCGTTACTAACTCAATCGATGAAACGTTTGTACCTTATGTAGAAAAAGCTTTAGGCTTAATTACAGAAGAAA
ATGGTATTACATCACCAAGTGCAATTGTTGGTTTAGAAAAAGGTATTCCAACAGTTGTAGGTGTAGAAAAAGCTGTTAAA
AACATAAGCAATAACATGTTAGTTACGATTGATGCTGCTCAAGGTAAAATCTTTGAAGGATATGCAAACGTACTATAA

Protein sequence : 
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDG
IIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNL
PGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLM
VARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYP
EEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAV
TPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVTNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQ
GIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVK
NISNNMLVTIDAAQGKIFEGYANVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-94 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 9e-94 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 9e-94 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-93 49
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 3e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_008585736.1 pyruvate kinase VFG0479 Protein 4e-94 49