Gene Information

Name : intA_4 (ECOPMV1_04739)
Accession : YP_008574436.1
Strain : Escherichia coli PMV-1
Genome accession: NC_022370
Putative virulence/resistance : Unknown
Product : Prophage CP4-57 integrase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4850490 - 4851743 bp
Length : 1254 bp
Strand : +
Note : -

DNA sequence :
ATGAAGCTCAATGCCAGACAGGTCGAAACCGCAAAGCCAAAAGAAAAAACCTACAAAATGGCCGATGGCGGCGGTTTGTA
TCTTGAGGTTTCGGCCAAGGGTTCCAAATACTGGCGTATGAAATACAGACGCCCCTCTGACAAAAAAGAGGATCGCCTTG
CTTTTGGTGTTTGGCCTACTGTGACGCTTGCTCAGGCAAGAGCAAAGCGCGATGAAGCTAAAAAGCTCTTAGTGCAGGGT
ATAGATCCGAAAACTGAACAGAAACAAGCTCACGCCGAAAATTCGGGGGCATATACTTTCGAAACCATTGCTCGTGAATG
GCATGCCAGCAACAAGCGATGGAGCGAAGACCATCGATCGCGCGTTCTTCGATACCTTGAGCTTTATATCTTCCCTCATA
TTGGTTCGTCCGATATTCGTCTACTCAAAACCAGCCACCTGTTAGCCCCAATTAAAAAAGTTGACGCCAGTGGAAAACAC
GACGTCGCTCAGCGCCTGCAACAGCGTGTAACGGCCATTATGCGTTATGCTGTACAAAACGATTACATCGACTCAAATCC
GGCCAGTGATATGGCTGGTGCGTTATCTACAACCAAAGTGCGACATTACCCTGCGTTACCTTCCAGCCGGTTACCTGAGT
TTCTTTCACGTCTCGCTGCATATCGTGGTCGTGTAATGACACGGATCGCAGTCGAGCTCTCCTTACTGACTTTTGTGCGT
TCCAGTGAGTTACGTTTCGCGCGTTGGAATGAGTTCGACTTCGATAAAGCCCTTTGGCGCGTACCTGCAAAACGAGAGGA
AATTAAGGGGGTGCGTTACTCGTATCGTGGTATGAAGATGAAAGAGGAGCATATTGTTCCGCTTAGTCGTCAGGCGATGA
ATTTGTTAGGCCAGTTAAAGCAGATTAGTGGTGATAGGAAACTGCTTTTCCCTGGCGATCATGACGCAACTAAGGTTATG
AGTGAAAACACAGTAAACAACGCATTGCGTGCGATGGGATATGACACTAAAACCGAAGTCTGTGGGCATGGGTTTAGGAC
GATGGCTCGAGGGGCATTAGGGGAGTCGGGTTTGTGGAGTGATGATGCTATTGAGCGTCAATTGAGTCACTCAGAGCGTA
ATAATGTGCGTGCAGCTTATATCCATACTTCTGAGCATTTGGATGAACGTCGTTTAATGATGCAGTGGTGGGCAGATTAT
ATAGATCATAATAAGATTATGTATACAACTCCGTTTGATTTTGCAAAAAAATAA

Protein sequence :
MKLNARQVETAKPKEKTYKMADGGGLYLEVSAKGSKYWRMKYRRPSDKKEDRLAFGVWPTVTLAQARAKRDEAKKLLVQG
IDPKTEQKQAHAENSGAYTFETIAREWHASNKRWSEDHRSRVLRYLELYIFPHIGSSDIRLLKTSHLLAPIKKVDASGKH
DVAQRLQQRVTAIMRYAVQNDYIDSNPASDMAGALSTTKVRHYPALPSSRLPEFLSRLAAYRGRVMTRIAVELSLLTFVR
SSELRFARWNEFDFDKALWRVPAKREEIKGVRYSYRGMKMKEEHIVPLSRQAMNLLGQLKQISGDRKLLFPGDHDATKVM
SENTVNNALRAMGYDTKTEVCGHGFRTMARGALGESGLWSDDAIERQLSHSERNNVRAAYIHTSEHLDERRLMMQWWADY
IDHNKIMYTTPFDFAKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 0.0 94
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 9e-111 58
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 3e-115 55
int AAK00456.1 Int Not tested SHI-1 Protein 6e-109 55
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 5e-116 55
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 3e-116 55
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 3e-116 55
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 3e-116 55
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 4e-116 55
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 2e-116 55
int AAL51003.1 CP4-like integrase Not tested LEE Protein 2e-116 55
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 2e-116 55
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 4e-117 55
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 6e-113 55
int AAK16198.1 Int Not tested PAI-I AL862 Protein 2e-117 55
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 6e-113 55
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 2e-117 55
int CAC81896.1 integrase Not tested LEE II Protein 9e-110 55
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 2e-110 54
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 2e-110 54
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 3e-116 54
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 2e-116 54
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 4e-117 54
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 3e-117 54
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 4e-117 54
int AAL51028.1 CP4-like integrase Not tested LEE Protein 3e-117 54
int-phe AAL60261.1 Int-phe Not tested LEE Protein 3e-117 54
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 4e-74 50
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 1e-86 49
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 2e-92 49
int CAA21384.1 - Not tested HPI Protein 1e-98 48
int CAB59974.1 integrase Not tested HPI Protein 8e-99 48
int CAA08754.1 integrase Not tested HPI Protein 4e-99 48
int YP_002346908.1 integrase Not tested HPI Protein 1e-98 48
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 1e-98 48
int2 NP_993013.1 integrase Not tested HPI Protein 1e-98 48
unnamed AAD17660.1 unknown Not tested HPI Protein 1e-95 47
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 1e-73 44
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 1e-73 44
ECs4534 NP_312561.1 integrase Not tested LEE Protein 1e-73 44
int AAC31482.1 CP4-like integrase Not tested LEE Protein 7e-74 44
int ACU09430.1 integrase Not tested LEE Protein 7e-74 44
int AAD44730.1 Int Not tested SHI-2 Protein 5e-75 44
int CAC39282.1 integrase Not tested LPA Protein 2e-75 44
aec33 AAW51716.1 Int Not tested AGI-3 Protein 2e-75 44
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 2e-74 44
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 3e-74 44
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 3e-74 44
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 6e-74 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
intA_4 YP_008574436.1 Prophage CP4-57 integrase VFG1536 Protein 5e-111 58
intA_4 YP_008574436.1 Prophage CP4-57 integrase VFG0626 Protein 1e-116 55
intA_4 YP_008574436.1 Prophage CP4-57 integrase VFG1693 Protein 1e-116 54
intA_4 YP_008574436.1 Prophage CP4-57 integrase VFG0783 Protein 4e-74 44
intA_4 YP_008574436.1 Prophage CP4-57 integrase VFG0598 Protein 1e-74 44