Gene Information

Name : kw2_0731 (kw2_0731)
Accession : YP_008568376.1
Strain : Lactococcus lactis KW2
Genome accession: NC_022369
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase/cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 734447 - 735586 bp
Length : 1140 bp
Strand : +
Note : -

DNA sequence :
ATGACAAGTTTAAAAACAAAAGTAATTCACGGTGGAATCTCAACAGATAGAACAACAGGAGCTGTTTCTGTTCCAATTTA
TCAAACATCAACTTATAAACAAAATGGACTTGGACAACCTAAAGAATATGAATATTCACGTTCAGGTAATCCGACACGAC
ATGCTTTGGAAGAATTAATTGCAGATTTAGAGGGTGGGGTTCAAGGTTTTGCTTTTAGTTCAGGCTTGGCTGGAATTCAC
GCGGTACTATCTTTATTTTCTGCGGGCGATCATATCATCTTAGCTGATGATGTTTACGGCGGAACTTTTCGATTGATGGA
CAAGGTGCTGACAAAGACAGGAATAATCTATGATTTAGTAGATTTGAGCAATCTTGACGATTTAAAGGCAGCTTTTAAAG
CAGAAACCAAAGCAGTCTACTTTGAAACGCCCTCAAATCCCCTCCTAAAAGTCTTGGATATCAAAGAAATTTCAAGGATT
GCTAAAGCTCATAATGCTCTAACATTAGTTGATAATACCTTTGCGACGCCTTATTTACAACAACCAATCACTCTAGGAGC
GGATATTGTCTTGCATTCTGCAACGAAATATTTAGGAGGACACTCAGATGTAGTGGCTGGTTTGGTAACGACAAATTCAA
ATGAACTCGCTAGTGAAATTGGCTTTTTACAAAATTCTATTGGAGCGGTTCTTGGTCCACAAGATAGCTGGTTAGTCCAA
AGAGGAATCAAAACACTTGCACTCCGGATGGAGGCCCATTCAGCAAATGCTCAAAAAATTGCTGAGTTTTTAGAAGCATC
ACAAGCTGTTTCAAAAGTCTATTATCCAGGTCTCGTCAATCATGAAGGACATGAGATTGCTAAAAAACAAATGACTGCTT
TTGGTGGAATGATTTCATTTGAATTGACTGACGAAAATGCGGTTAAAAATTTTGTTGAAAACTTGCGCTATTTTACACTA
GCCGAATCACTCGGAGGAGTCGAATCTTTGATTGAAGTGCCAGCAGTAATGACTCATGCCTCAATTCCTAAAGAACTTCG
GGAAGAAATTGGGATAAAAGATGGATTGATTCGCTTATCAGTCGGTGTTGAAGCTCTTGAAGATTTACTGACGGACCTCA
AAGAAGCACTCGAAAAATAA

Protein sequence :
MTSLKTKVIHGGISTDRTTGAVSVPIYQTSTYKQNGLGQPKEYEYSRSGNPTRHALEELIADLEGGVQGFAFSSGLAGIH
AVLSLFSAGDHIILADDVYGGTFRLMDKVLTKTGIIYDLVDLSNLDDLKAAFKAETKAVYFETPSNPLLKVLDIKEISRI
AKAHNALTLVDNTFATPYLQQPITLGADIVLHSATKYLGGHSDVVAGLVTTNSNELASEIGFLQNSIGAVLGPQDSWLVQ
RGIKTLALRMEAHSANAQKIAEFLEASQAVSKVYYPGLVNHEGHEIAKKQMTAFGGMISFELTDENAVKNFVENLRYFTL
AESLGGVESLIEVPAVMTHASIPKELREEIGIKDGLIRLSVGVEALEDLLTDLKEALEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-96 55
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-97 55
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-73 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
kw2_0731 YP_008568376.1 cystathionine gamma-synthase/cystathionine beta-lyase BAC0207 Protein 6e-71 43