Gene Information

Name : LY180_22420 (LY180_22420)
Accession : YP_008567485.1
Strain : Escherichia coli LY180
Genome accession: NC_022364
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4689357 - 4690625 bp
Length : 1269 bp
Strand : +
Note : Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence : 
ATGGCCCTAACGGATACTAAAGTTCGCTCTGCGAAACCTGAGGAGAAAGAGTATTCACTTGTTGACGGTGACGGCATGTC
TTTACTTGTAAAACCTGGCGGCTCCAAGTATTGGCGATTTCGTTTCCGTTTCGGCGGTAAACAACATTTGATGGCGTTCG
GCGTTTACCCGGATGTTTCGCTGGCGGATGCGCGGAAGAAAAGGGAAGAGGCCAGAAAGCTGGTCGCTGCTGGTATCGAT
CCTCGTGAGCATAAACGTGCTGTGAAAGAAGAGCAGGCGAAAGAGATTATTACTTTCGAGAAGGTTGCCAGAGAGTGGCT
CGTAACCAACCAAAAATGGTCGGAAGATCATGCTAATCGTGTAAAAAAGAGCCTGGAGGACAATATCTTCCCGGCAATTG
GTACTCGCAACATTGCTGAACTAGGCACCCGCGATCTGTTAATTCCTATTAAAGCCGTGGAGAAATCCGGACGCCTTGAA
GTGGCTTCCCGCCTTCAACAGCGCACCACGGCCATCATGCGGTATGCGGTGCAAAGTGGGTTAATTGATTATAACCCAGC
ACAAGAGATGGCTGGGGCGGTTGCTTCCAGTAATCGACAACATCGTCCGGCGCTGGAGTTAAAGCGCATCCCTGAGTTAC
TTGAGAAAATAGATGGCTACACCGGCAGGCCACTAACCCGCTGGGCAACCGAACTTACTCTGCTTATTTTTATTCGATCC
AGTGAGCTGCGTTTTGCTCGCTGGTCAGAGATCGATTTTGAAACATCAATGTGGACCATCCCTCCTGAGCGAGAACCGAT
TCCCGGCGTGAAATATTCTCAGCGAGGATCAAAGATGCGTACACCTCATCTGGTGCCGCTTTCAAAACAGGCGCTGGCGA
TCCTGAAGCAGATAAAACAGTTCTGTGGCGAACATGAGCTGATTTTTATTGGCGATCACGATCCGCGTAAGCCCATGAGC
GAGAACACGGTTAACAGTGCGCTACGGGTGATGGGTTATGACACTAAGGTTGAAGTTTGCGGCCACGGTTTCCGCACAAT
GGCCTGTAGTTCGTTAATTGAGTCAGGACTATGGTCGAAGGATGCGGTGGAAAGGCAGATGAGCCATATGGAACGCAATT
CGGTGAGGGCGGCGTATATCCATAAAGCGGAACATCTTGATGAGCGCAAGCTGATGTTGCAGTGGTGGGCGGATTTTCTG
GATGCGAATCGGGAGAGAGCGATTACGCCGTTTGACTATGCGAAGATCAATCGGGGTAATAGCGAGTGA

Protein sequence : 
MALTDTKVRSAKPEEKEYSLVDGDGMSLLVKPGGSKYWRFRFRFGGKQHLMAFGVYPDVSLADARKKREEARKLVAAGID
PREHKRAVKEEQAKEIITFEKVAREWLVTNQKWSEDHANRVKKSLEDNIFPAIGTRNIAELGTRDLLIPIKAVEKSGRLE
VASRLQQRTTAIMRYAVQSGLIDYNPAQEMAGAVASSNRQHRPALELKRIPELLEKIDGYTGRPLTRWATELTLLIFIRS
SELRFARWSEIDFETSMWTIPPEREPIPGVKYSQRGSKMRTPHLVPLSKQALAILKQIKQFCGEHELIFIGDHDPRKPMS
ENTVNSALRVMGYDTKVEVCGHGFRTMACSSLIESGLWSKDAVERQMSHMERNSVRAAYIHKAEHLDERKLMLQWWADFL
DANRERAITPFDYAKINRGNSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 7e-160 83
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 3e-146 68
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 3e-146 68
int AAK00456.1 Int Not tested SHI-1 Protein 5e-137 68
int AAK16198.1 Int Not tested PAI-I AL862 Protein 9e-146 68
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 9e-146 68
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 8e-146 68
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 1e-143 67
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 2e-145 67
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 1e-145 67
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 2e-145 67
int CAC81896.1 integrase Not tested LEE II Protein 2e-135 67
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 9e-143 67
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 3e-144 67
int AAL51003.1 CP4-like integrase Not tested LEE Protein 1e-144 67
int-phe AAL60261.1 Int-phe Not tested LEE Protein 1e-144 66
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 9e-144 66
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 7e-144 66
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 1e-144 66
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 1e-144 66
int AAL51028.1 CP4-like integrase Not tested LEE Protein 1e-144 66
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 1e-144 66
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 9e-135 64
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 9e-135 64
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 1e-83 59
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 2e-96 58
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 7e-118 57
int CAA08754.1 integrase Not tested HPI Protein 4e-112 57
int CAB59974.1 integrase Not tested HPI Protein 9e-113 57
int YP_002346908.1 integrase Not tested HPI Protein 1e-111 56
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 1e-111 56
int2 NP_993013.1 integrase Not tested HPI Protein 1e-111 56
int CAA21384.1 - Not tested HPI Protein 1e-111 56
unnamed AAD17660.1 unknown Not tested HPI Protein 3e-108 55
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 1e-115 54
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 1e-115 54
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 5e-105 53
int AAD44730.1 Int Not tested SHI-2 Protein 5e-84 44
int CAC39282.1 integrase Not tested LPA Protein 4e-84 44
aec33 AAW51716.1 Int Not tested AGI-3 Protein 3e-84 44
int AAC31482.1 CP4-like integrase Not tested LEE Protein 2e-82 44
int ACU09430.1 integrase Not tested LEE Protein 2e-82 44
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 2e-82 44
ECs4534 NP_312561.1 integrase Not tested LEE Protein 2e-82 44
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 2e-75 43
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 2e-82 43
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 2e-82 43
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 1e-82 43
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 7e-73 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LY180_22420 YP_008567485.1 integrase VFG1536 Protein 4e-160 83
LY180_22420 YP_008567485.1 integrase VFG0626 Protein 1e-146 68
LY180_22420 YP_008567485.1 integrase VFG1693 Protein 3e-144 66
LY180_22420 YP_008567485.1 integrase VFG0783 Protein 9e-83 44
LY180_22420 YP_008567485.1 integrase VFG0598 Protein 8e-83 43