Gene Information

Name : tpx (LY180_06740)
Accession : YP_008564461.1
Strain : Escherichia coli LY180
Genome accession: NC_022364
Putative virulence/resistance : Virulence
Product : lipid hydroperoxide peroxidase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1425658 - 1426164 bp
Length : 507 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homolog

DNA sequence :
ATGTCACAAACCGTTCATTTCCAGGGCAACCCGGTTACAGTCGCCAATTCCATCCCGCAGGCGGGTAGCAAAGCGCAGAC
TTTTACTCTCGTGGCAAAAGATCTGTCTGACGTCACCCTCGGTCAGTTTGCGGGTAAACGCAAAGTGCTGAACATTTTCC
CGAGTATTGATACCGGTGTTTGCGCCGCATCAGTACGTAAGTTTAACCAACTGGCAACCGAGATCGACAACACCGTTGTG
CTGTGTATTTCTGCCGATCTGCCGTTCGCCCAGTCTCGTTTCTGCGGCGCAGAAGGTCTGAACAACGTTATCACCCTCTC
CACTTTCCGTAACGCTGAATTCCTGCAAGCCTACGGTGTGGCAATTGCTGATGGCCCACTGAAAGGTCTGGCAGCGCGTG
CCGTTGTGGTTATTGATGAAAATGACAATGTGATTTTCAGCCAGCTGGTGGATGAAATCACCACCGAGCCGGATTACGAA
GCAGCTCTGGCGGTACTGAAAGCATAA

Protein sequence :
MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFAGKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVV
LCISADLPFAQSRFCGAEGLNNVITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYE
AALAVLKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 4e-36 48
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 2e-36 48
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 6e-36 48
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 3e-36 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_008564461.1 lipid hydroperoxide peroxidase VFG0087 Protein 9e-37 48