Gene Information

Name : ureC (HifGL_000309)
Accession : YP_008543449.1
Strain : Haemophilus influenzae KR494
Genome accession: NC_022356
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 313544 - 315262 bp
Length : 1719 bp
Strand : +
Note : amino acid transport and metabolism

DNA sequence :
ATGACATTAACAATTTCAAGAGCACAATATGTAGCAACTTATGGCCCAACCGTTGGCGATAAAGTCCGTTTAGGCGATAC
CAATTTATGGGCAACTATTGAACAAGATTTATTGACCAAAGGCGATGAGTGTAAATTTGGTGGCGGTAAAAGTGTGCGTG
ATGGCATGGCTCAAAGTGGTACGGCAACTCGTGACAATCCAAATGTATTGGATTTTGTGATTACCAACGTGATGATTATT
GATGCCAAATTAGGCATTATCAAAGCGGATATTGGTATTCGTGATGGTCGCATTGTGGGCATCGGTCAAGCTGGTAACCC
TGACACCATGGATAATGTCACGCCAAATATGATTATCGGTGCAAGCACGGAAGTGCATAACGGTGCTCATTTAATTGCGA
CCGCTGGCGGTATTGATACGCATATTCACTTTATTTGCCCTCAACAAGCACAGCATGCGATTGAAAGTGGGGTTACCACG
CTAATTGGTGGCGGAACAGGCCCTGCTGATGGTACACACGCGACTACTTGTACACCGGGTGCGTGGTATATGGAGCGTAT
GTTCCAAGCAGCAGAAGCATTGCCTGTAAACGTAGGCTTTTTTGGTAAAGGAAACTGCTCAACTTTAGATCCGCTACGCG
AACAAATTGAAGCAGGTGCATTAGGTTTAAAAATCCACGAAGACTGGGGCGCAACACCTGCAGTAATTGATTCAGCATTA
AAAGTGGCTGATGAAATGGATATTCAAGTGGCAATCCACACCGATACGCTGAACGAAAGTGGCTTTTTAGAAGATACGAT
GAAAGCAATTGATGGACGTGTAATTCATACCTTCCATACAGAAGGTGCGGGTGGCGGACACGCTCCTGATATTATTAAAG
CAGCGATGTATCCAAACGTATTGCCTGCTTCAACCAACCCGACTCGTCCATTTACGAAAAACACCATTGATGAACATTTA
GATATGTTGATGGTTTGCCATCACTTAGATAAACGCGTGCCAGAAGATGTGGCATTTGCCGATAGCCGTATTCGTCCTGA
AACTATTGCAGCGGAGGATATTTTGCACGATATGGGCGTTTTCTCCATTATGAGTTCTGACTCTCAAGCAATGGGACGTA
TTGGCGAAGTCGTTATTCGTACTTGGCAAACCGCTGATAAAATGAAAATGCAACGTGGTGAGCTAGGTAATGAAGGAAAC
GATAACTTCCGCATTAAACGCTACATTGCGAAATACACTATCAACCCAGCAATTGCACACGGTATTGAAGATCATATTGG
TTCGTTAGAAGTGGGCAAAATTGCAGATATTGTGTTATGGAAACCGATGTTCTTTGGGGTAAAACCAGAAGTAGTAATTA
AAAAAGGCTTTATTAGCTATGCGAAAATGGGCGACCCAAATGCCTCAATTCCAACACCGCAACCTGTATTCTACCGTCCA
ATGTATGGCGCACAAGGCTTAGCGACAGCACAAACCGCGGTATTCTTTGTTTCACAAGCCGCTGAAAAAGCAGATATTCG
TGCGAAATTCGGTTTACACAAAGAAACCATTGCTGTGAAAGGCTGCCGCAGTGTGGGTAAAAAAGATCTCGTTCACAACA
ATGCAACACCAAATATTACTGTTGATGCTGAACGTTATGAAGTTCGAGTGGACGGAGAGTTAATTACCTGTGAACCCGTG
GATACCGTGCCGTTAGGACAACGATATTTTATGTTCTAA

Protein sequence :
MTLTISRAQYVATYGPTVGDKVRLGDTNLWATIEQDLLTKGDECKFGGGKSVRDGMAQSGTATRDNPNVLDFVITNVMII
DAKLGIIKADIGIRDGRIVGIGQAGNPDTMDNVTPNMIIGASTEVHNGAHLIATAGGIDTHIHFICPQQAQHAIESGVTT
LIGGGTGPADGTHATTCTPGAWYMERMFQAAEALPVNVGFFGKGNCSTLDPLREQIEAGALGLKIHEDWGATPAVIDSAL
KVADEMDIQVAIHTDTLNESGFLEDTMKAIDGRVIHTFHTEGAGGGHAPDIIKAAMYPNVLPASTNPTRPFTKNTIDEHL
DMLMVCHHLDKRVPEDVAFADSRIRPETIAAEDILHDMGVFSIMSSDSQAMGRIGEVVIRTWQTADKMKMQRGELGNEGN
DNFRIKRYIAKYTINPAIAHGIEDHIGSLEVGKIADIVLWKPMFFGVKPEVVIKKGFISYAKMGDPNASIPTPQPVFYRP
MYGAQGLATAQTAVFFVSQAAEKADIRAKFGLHKETIAVKGCRSVGKKDLVHNNATPNITVDAERYEVRVDGELITCEPV
DTVPLGQRYFMF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-172 64
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-172 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-147 61
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-147 61
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-146 61
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-147 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_008543449.1 urease subunit alpha VFG0270 Protein 3e-158 62