Gene Information

Name : topB (HifGL_000032)
Accession : YP_008543172.1
Strain : Haemophilus influenzae KR494
Genome accession: NC_022356
Putative virulence/resistance : Unknown
Product : DNA topoisomerase-3
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 35123 - 37078 bp
Length : 1956 bp
Strand : -
Note : DNA replication, recombination and repair

DNA sequence :
ATGCGTTTATTTATCGCCGAAAAACCAAGCCTAGCTCGCGCTATTGCAGATGTGCTACCTAAACCCCATCAACGTGGGGA
CGGTTTTATTAAATGTGGCGATAATGATGTGGTAACTTGGTGTGTAGGGCATTTGCTCGAGCAAGCAGAACCCGATGCCT
ATGATCCTAAATTCAAACAATGGCGTTTAGAACATCTCCCTATTATTCCTGAAAAATGGCAACTTTTACCGCGAAAAGAA
GTAAAAAAACAGCTTTCTGTGGTGGAAAAACTGATCCATCAAGCGGATACACTTGTTAATGCAGGAGACCCAGATAGAGA
AGGACAATTACTTGTAGATGAAGTGTTCAGTTATGCCAATTTAGCTGCTGAAAAACACGACAAAATTTTACGCTGCTTGA
TTAGCGACCTAAATCCAAGTGCGGTAGAAAAAGCAGTAAAAAAATTACAACCTAACCGTAACTTTATTCCTCTTGCCACA
TCCGCACTCGCACGAGCCCGCGCCGATTGGCTTTATGGCATTAATATGACCAGAGCATATACCATTCGTGGCAGACAAAC
TGGCTATGATGGCGTGCTTTCGGTTGGTCGAGTGCAAACCCCTGTGCTGGGTTTAATTGTACGTCGAGATTTGGAAATTG
AACATTTCCAGCCCAAAGACTTTTTTGAAGTACTAGCTTGGATTAATCCAGAGAGTAAAGAAGAAAAAACTCGGGAGAAA
TCAACCGCACTTTTCAGTGCCTTATGGCAACCCAGCAAAGCTTGTGAAGATTACCAAGATGATGATGGCAGAGTACTTTC
TAAAGGCTTAGCTGAAAACGTTGTAAAACGTATTACAAATCAACCTGCGGAAGTAACCGAATACAAAGACGTTCGTGAAA
AAGAAACGCCACCCTTGCCTTATTCCCTTTCTGCGTTGCAAATTGATTCGGCAAAGCGATTCGGTATGTCCGCTCAAGCC
GTATTAGATACTTGCCAACGCCTGTATGAAACTCATCGTTTGATTACTTATCCGCGTTCTGATTGTCGCTATTTGCCCGA
AGAACATTTTGCCGAACGCCATAACGTATTAAATGCAATTTCAACCCATTGTGAAACTTATCAACGCTTACCAAATGTTA
TTTCAACTGAACAGAGAAATCGTTGTTGGAATGATAAAAAAGTAGAAGCTCACCACGCAATTATCCCGACAGCCAAAAAT
CGTCCAGTAAATCTAACACAAGAAGAACGTAATATTTACAGCCTTATCGCTCGCCAATATTTAATGCAATTTTGCCCTGA
CGCAGAATATCGTAAAAGCAAAATCACATTAAACATTGCTGGCGGTACCTTTATAGCTCAAGCGCGAAATTTACAAACCG
CTGGGTGGAAAGAGTTATTAGGCAAAGAAGACGACACAGAAAATCAAGAACCCTTATTACCCATAGTAAAGAAAGGACAA
ATTTTGCATTGTGAACGTGGAGAAGTCATTAGTAAAAAAACTCAACCGCCAAAGCCTTTCACAGATGCAACCTTGCTTTC
AGCAATGACGGGTATTGCGCGATTTGTACAGGATAAAGAACTCAAAAAAATCCTGCGAGAAACGGATGGATTGGGCACAG
AGGCTACTCGCGCTGGCATCATTGAGTTACTTTTTAAACGCGGTTTTTTAACGAAAAAAGGGCGAAATATTCACAGTACA
GAAACAGGAAGAATTTTAATTCAGGCATTACCAGATATTGCCACCCAACCAGATATGACAGCTCATTGGGAATCGCAACT
CACAGACATTAGTCAAAAACAAGCAAGCTATCAGCAATTTATGCATAACTTGAATCAAATGCTGCCTGATTTAGTCCGTT
TTGTAGATCTTAATGCATTAAGACAATTAAGTCGCATTAAAATGATTAAATCTGATAGAGCAAAACCTAAAAGTGCGGTA
AAAAAATCGAGTAAATCAAACGGTGAAACTGATTAA

Protein sequence :
MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGDNDVVTWCVGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLLPRKE
VKKQLSVVEKLIHQADTLVNAGDPDREGQLLVDEVFSYANLAAEKHDKILRCLISDLNPSAVEKAVKKLQPNRNFIPLAT
SALARARADWLYGINMTRAYTIRGRQTGYDGVLSVGRVQTPVLGLIVRRDLEIEHFQPKDFFEVLAWINPESKEEKTREK
STALFSALWQPSKACEDYQDDDGRVLSKGLAENVVKRITNQPAEVTEYKDVREKETPPLPYSLSALQIDSAKRFGMSAQA
VLDTCQRLYETHRLITYPRSDCRYLPEEHFAERHNVLNAISTHCETYQRLPNVISTEQRNRCWNDKKVEAHHAIIPTAKN
RPVNLTQEERNIYSLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQTAGWKELLGKEDDTENQEPLLPIVKKGQ
ILHCERGEVISKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLTKKGRNIHST
ETGRILIQALPDIATQPDMTAHWESQLTDISQKQASYQQFMHNLNQMLPDLVRFVDLNALRQLSRIKMIKSDRAKPKSAV
KKSSKSNGETD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 2e-102 41