Gene Information

Name : guaA (HifGL_001619)
Accession : YP_008544709.1
Strain : Haemophilus influenzae KR494
Genome accession: NC_022356
Putative virulence/resistance : Unknown
Product : GMP synthetase (glutamine aminotransferase)
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1670309 - 1671880 bp
Length : 1572 bp
Strand : +
Note : nucleotide transport and metabolism

DNA sequence :
ATGACAAATATCCACAATCACAAAATCCTGATCCTCGACTTCGGTTCACAATATACTCAACTGATTGCGCGTCGTGTGCG
TGAAATTGGTGTGTACTGCGAACTTTGGGCTTGGGATGTAACCGAACAACAAATCCGTGAATTTGCTCCAACGGGTATCA
TTCTTTCTGGCAGTCCTGAAAGCACAACTGAAGAAAACAGCCCACGTGCGCCTGAATATGTGTTTAACGCAGGCGTTCCA
GTGCTCGGCGTTTGCTATGGAATGCAAACTATGGCGATGCAACTTGGCGGCTTAACCGAAACATCTGATCACAGAGAGTT
CGGCTATGCTTCAGTTTCTCTTGAAAATTCCACCGCACTTTTTGCAAATTTAAACGATAATTCGACCGCTTCTGAGCCAA
AATTAGACGTTTGGATGAGCCACGGCGATAAGGTAACGCGCTTACCAGAAAACTTCAAAGTAACTGGCACAACGCTAACC
TGCCCTATCGCAGCAATGTCAGACGAAAGCCGTCGTTTCTACGGTGTGCAGTTCCACCCTGAAGTAACGCATACTAAAAA
AGGCTTGGAATTATTAACCAACTTCGTAGTAAACATCTGTGGTTGCGAAACCAAATGGACAGCTGAAAACATTATCGAAG
ATGCCGTTGCTCGCATCAAAGAACAAGTGGGCGATGATGAAGTGATTTTAGGCTTATCTGGTGGTGTGGACTCTTCTGTG
GTTGCATTACTTTTACACCGTGCTATCGGCAAAAACTTACACTGCGTATTTGTGGATAACGGTTTGCTTCGCTTACACGA
AGGCGATCAAGTCATGGAAATGTTTGGCGATAAATTCGGTTTAAACATCACTCGTGTTGATGCAGAAAGCCGCTTCCTAG
GCGAACTTGCAGGGGTATCAGATCCTGAAGCGAAACGTAAAATTATCGGTAAAGTATTCGTTGATGTATTCGATGATGAA
TCGAAAAAACTCACTAATGTGAAATGGTTGGCACAAGGTACGATCTACCCTGATGTGATCGAATCTGCAGCAAGCAAAAC
TGGTAAAGCACATGTGATTAAATCACACCACAACGTAGGTGGCTTACCAGACTATATGAAACTGGGCTTAGTTGAACCAT
TACGTGAATTGTTTAAAGATGAAGTACGTAAAATCGGTCTAGCATTAGGCTTACCAGCTGAAATGATCAACCGCCACCCA
TTCCCTGGTCCAGGTTTAGGCGTACGTATATTAGGCGAAGTGAAAAAAGAATACTGCGATTTATTACGCCGTGCGGATGC
AATCTTTATCGAAGAATTACGCAACAGCGGTTGGTATGAAAAAACCAGCCAAGCCTTCAGTGTATTCTTGCCTGTGAAAT
CTGTTGGTGTAATGGGCGATGGGCGTAAATACGATTGGGTTATTTCTCTACGCGCAGTAGAAACCATCGATTTTATGACC
GCACATTGGGCACATTTGCCTTATGATTTATTAGGTAAAGTATCTAACCGCATCATCAACGAAGTGAACGGCATTTCCCG
CGTCGTATATGACATTAGCGGGAAACCGCCAGCGACAATCGAGTGGGAATAG

Protein sequence :
MTNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEQQIREFAPTGIILSGSPESTTEENSPRAPEYVFNAGVP
VLGVCYGMQTMAMQLGGLTETSDHREFGYASVSLENSTALFANLNDNSTASEPKLDVWMSHGDKVTRLPENFKVTGTTLT
CPIAAMSDESRRFYGVQFHPEVTHTKKGLELLTNFVVNICGCETKWTAENIIEDAVARIKEQVGDDEVILGLSGGVDSSV
VALLLHRAIGKNLHCVFVDNGLLRLHEGDQVMEMFGDKFGLNITRVDAESRFLGELAGVSDPEAKRKIIGKVFVDVFDDE
SKKLTNVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMINRHP
FPGPGLGVRILGEVKKEYCDLLRRADAIFIEELRNSGWYEKTSQAFSVFLPVKSVGVMGDGRKYDWVISLRAVETIDFMT
AHWAHLPYDLLGKVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-130 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-130 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-130 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-110 48