Gene Information

Name : hsdM1 (HifGL_001241)
Accession : YP_008544349.1
Strain : Haemophilus influenzae KR494
Genome accession: NC_022356
Putative virulence/resistance : Unknown
Product : putative type I restriction enzyme HindVII
Function : -
COG functional category : -
COG ID : -
EC number : 2.1.1.72
Position : 1247815 - 1249545 bp
Length : 1731 bp
Strand : +
Note : defense mechanisms

DNA sequence :
TTGAATATTCAAACTTCCGATAAAAATCACTTTACAGAGGGCATAATTTATGCAAGCGAGACGACCAAGATTGTCGATGA
AAATCATGCATTACAACAAGCATTTTTAAATGAATTAGACGAAAAACTTTGGTCATCTGCGGATAAACTCCGTCAACAAC
TTGATGCCGCCAATTATAAACATATCGTTCTTGGTCTTATCTTTTTAAAATACATTTCTGATAATTTCACCCATCAACAG
GAAAAAATTCAGGCGGAACTCTCCACACCTGAAAACCCACTCTATCTTGACCGCACTTTTTTTGATACTGAAGAAGAATA
TCAAGAAGCCTTAACCGCTGAACTAGAAAACCGTGATTATTACACCGCGGATAACGTATTTTGGGTGCCAGCTTCTGCAC
GTTGGCAAGCCTTACAAGAAGTTTCTATTCTCAATACTGGGGCAGAATTGCCTTGGAATATAGGAAAGGAGCGTGGGAAG
TTTTCTGGTGTGGCAAAGCTCATTGATGATGCCTTTGATGCTATTGAAAAAGATAACGAAAAACTCAAAGGCGTACTCCA
ACGCATCAGTGGCTATGCGGTAAACGAAGACACCCTGCGCGGGCTGATTATCCTCTTCTCCGATACTAATTTTACCCGTC
CGACTTACAACGGCGAGCCCGTGCATTTAGGTGCAAAAGACATTCTTGGCCACGTTTACGAATACTTCCTTGGTCGCTTT
GCCCAAGCCGAAGGCAAGCGCGGCGGCCAATATTTCACGCCGAAATCCATTGTTTCCCTGATTGTCGAAATGCTCGAACC
ATACTCCGGCCGAGTGTATGATCCAGCCATGGGCAGCGGCGGCTTTTTCGTGCAAACCGAACGCTTTATCTCCGCCCATC
AAGGCAACATCAATAACGTTTCCATCTACGGGCAAGAATTCAACCCCACCACATGGAAACTTGCGGCGATGAATATGGCG
ATTCGCGGCATTGATTACGACTTCGGCAAACACAACGCCGACAGCTTTACGCAGCCGCAACATATCGACAAAAAGATGGA
TTTCATTATGGCAAACCCGCCATTCAATATCAGCGATTGGTGGAGCGAATCCCTTGCCGACGACCCACGTTGGGCATACG
GCACGCCGCCCAAAGGCAATGCCAACTTCGCTTGGCTGCAACACATGATTTACCACCTCTCGCCCAACGGCAAAATGGCA
TTATTGCTTGCCAACGGCTCCATGAGCAGCCAAACCAACAACGAAGGCGAAATCCGCAAAGCCATCATCAATGCCGACTT
AGTGGAATGTATGGTTGCCCTGCCTGGTCAGCTCTTCACCAACACCCAAATCCCCGCCTGCATTTGGTTTCTAAACCGCA
ACAAAAAGCGTAAAGGCGAAGTATTGTTTATCGATGCCCGCCAAATCGGCTATATGAAAGACCGCGTATTGCGCGATTTT
ACCGCTGACGACATCGCCAAAATCGCCAATACCCTCCACGCTTGGCAAAAATCAGACGGCTATGAAGACCAAGCCGCTTT
CTGCAAATCCACTACGTTAGAAGAAATTAAAGACAACGACTTCGTCCTCACACCGGGACGCTACGTCGGCACCGCAGAAC
AAGAAGACGACGGCGTACCATTTGCAGAAAAAATGCAAAATCTGACCGCTCTTTTGAAGGAGCAATTTGCGAAAAGTGCG
GAATTAGAAGCGGAAATTAAGAAGAATTTAGGAGGATTGGGGTATGAGTGA

Protein sequence :
MNIQTSDKNHFTEGIIYASETTKIVDENHALQQAFLNELDEKLWSSADKLRQQLDAANYKHIVLGLIFLKYISDNFTHQQ
EKIQAELSTPENPLYLDRTFFDTEEEYQEALTAELENRDYYTADNVFWVPASARWQALQEVSILNTGAELPWNIGKERGK
FSGVAKLIDDAFDAIEKDNEKLKGVLQRISGYAVNEDTLRGLIILFSDTNFTRPTYNGEPVHLGAKDILGHVYEYFLGRF
AQAEGKRGGQYFTPKSIVSLIVEMLEPYSGRVYDPAMGSGGFFVQTERFISAHQGNINNVSIYGQEFNPTTWKLAAMNMA
IRGIDYDFGKHNADSFTQPQHIDKKMDFIMANPPFNISDWWSESLADDPRWAYGTPPKGNANFAWLQHMIYHLSPNGKMA
LLLANGSMSSQTNNEGEIRKAIINADLVECMVALPGQLFTNTQIPACIWFLNRNKKRKGEVLFIDARQIGYMKDRVLRDF
TADDIAKIANTLHAWQKSDGYEDQAAFCKSTTLEEIKDNDFVLTPGRYVGTAEQEDDGVPFAEKMQNLTALLKEQFAKSA
ELEAEIKKNLGGLGYE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-177 64
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 7e-127 50
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 6e-127 50
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 2e-124 49