Gene Information

Name : N646_0826 (N646_0826)
Accession : YP_008535196.1
Strain :
Genome accession: NC_022349
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 915789 - 917408 bp
Length : 1620 bp
Strand : +
Note : -

DNA sequence : 
ATGACGAACATACAGCACACGTTAGATTTTACACCATGGCCACAAGAGTCCGCTCGGTACTATCGGGCAAAGGGATATTG
GCAAGATAAAACATTATTCGACCATTTGCTGGACTCGGTTAAGACTCATCCAGATGCTTTAGCCATCATCAGTGGTGAAT
GCTCATACACCTTTCAACAGTTGCATGACAAAGTCACCCAGCTCGCCGCAGGATTCATTACATTAGGCCTGAAATCGGGT
GACAATGTTGTCATGCAAATCAGCAATCGAGCGGAGTTTTATATCTGCTTCTTTGCACTAACCATGCAAGGGATAAAGCC
AGTTGTTGCACTGCCAGCTCACCGAACTCTTGAGCTCAGCTATTTTTGTCGTCACGCACAAGCAAAAGCGTATATTTTCT
CTGATGACACGCCGGGTTTTGATGCCCAAAAGACGGCCTTAACTTTGCAGGATGAATGTGCATCATTGTCATACCTCATT
CACACAGACCAATCGGTAGATTCTCAAATTACCGAATTAAGCACGCTTTATGAAGCGCAAGGTATTGCTCAAAACAGCAA
TGCTAACCATGTAGCTTTCTTCCAGCTGTCTGGTGGCACTACAGGCACTCCAAAGCTGATCCCAAGAACACACAATGACT
ACGCATATAGCGTTATCGCAAGTAATGCAATATGTAACTTCAGTGAACAAACACGCTATCTGTGCGTATTGCCAGCAGCA
CATAACTTCCCATTAAGTTCCCCGGGTGCGTTAGGCGTTTTCTTTGCTGGAGGCTGTGTGGTATTGGCACAAGATAGCTC
ACCACAAAATGCGTTCAAGCTGATTGAACAACATAGGATCACCGTCTCCGCTCTTGTACCACCACTCGCGTTACTTTGGA
TGAAACATGCAGAGACTGCCGATGACGATATTTCTAGCCTTAAATTTGTGCAAGTTGGTGGCGCCAAGTTCAGTGAAACC
ACAGCCAGAGAGCTACCTAATAAGCTAAACTGCCAATTACAACAAGTCTTTGGAATGGCGGAAGGTTTGGTCAACTATAC
ACGTTTAGATGACCCGATTGATGTCATCGTAAAAACACAAGGGCGGCCAATGTCGCCAGACGATGAAGTGCTCGTGGTTG
ATGACGAAGGCAAACCCGTCCCTGTTGGTGAAGAAGGTGCACTATTAACCCGAGGCCCATATACGATCCAAGGTTATTTC
CGCGCCAAAGAACACAATCAACGTTCATTTAACGCAGAACGATTTTACGCCACGGGAGATCTCGTTCGGCTAACCTCTGA
CGGCAACATCATTGTTACTGGACGTGATAAAGACCAAATCAACCGAGGAGGAGAAAAAATCGCCGCAGAAGAAGTAGAAA
ACCTGATACTTCAACATGACAGCGTACATGATGTCGCTTTAGTCGCCATACCTGATGAGTTTCTGGGCGAGCGCAGCTGT
GCGATTATTGTTCCTGAAAGCAACCAGAAACCAAAACCTGTTGAACTAAAACGCTTCTTGCACAGTCAAGGACTTGCTCA
ATTCAAGATTCCTGACCAAATCCATTTTGCTGAAGCCTTACCGAAAACTCCGGTAGGCAAAATAAACAAGAAAGTGTTAA
GAGAACAATTCTCTTCATAA

Protein sequence : 
MTNIQHTLDFTPWPQESARYYRAKGYWQDKTLFDHLLDSVKTHPDALAIISGECSYTFQQLHDKVTQLAAGFITLGLKSG
DNVVMQISNRAEFYICFFALTMQGIKPVVALPAHRTLELSYFCRHAQAKAYIFSDDTPGFDAQKTALTLQDECASLSYLI
HTDQSVDSQITELSTLYEAQGIAQNSNANHVAFFQLSGGTTGTPKLIPRTHNDYAYSVIASNAICNFSEQTRYLCVLPAA
HNFPLSSPGALGVFFAGGCVVLAQDSSPQNAFKLIEQHRITVSALVPPLALLWMKHAETADDDISSLKFVQVGGAKFSET
TARELPNKLNCQLQQVFGMAEGLVNYTRLDDPIDVIVKTQGRPMSPDDEVLVVDDEGKPVPVGEEGALLTRGPYTIQGYF
RAKEHNQRSFNAERFYATGDLVRLTSDGNIIVTGRDKDQINRGGEKIAAEEVENLILQHDSVHDVALVAIPDEFLGERSC
AIIVPESNQKPKPVELKRFLHSQGLAQFKIPDQIHFAEALPKTPVGKINKKVLREQFSS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-99 45
ybtE CAA21394.1 - Virulence HPI Protein 1e-99 45
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-99 45
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 8e-99 45
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 9e-100 45
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-98 45
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-99 45
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-99 45
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-99 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
N646_0826 YP_008535196.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 3e-120 49
N646_0826 YP_008535196.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 7e-121 49
N646_0826 YP_008535196.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 7e-99 42