Gene Information

Name : guaA (M892_07535)
Accession : YP_008526273.1
Strain :
Genome accession: NC_022269
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1638658 - 1640211 bp
Length : 1554 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGACTAAAAATATTCATGACCAACGTATTCTGATCTTGGACTTCGGTTCTCAGTACACTCAGCTAGTAGCGCGCCGTGT
ACGTGAAATCGGTGTTTACTGTGAACTGTGGAGCTGGGACGTTGAAGAAGCGGATATTCGTGAATTCAATCCAGACGGTA
TCATCCTATCTGGTGGTCCAGAAAGCGTAACGGAAGACAACTCTCCACGCGCTCCTCAATACGTATTTGACTCTGGTGTG
CCAGTACTAGGTGTGTGTTACGGCATGCAAACTATGGCTGAGCAGCTAGGTGGTAAAGTTGCGGGTTCTACTGAACGTGA
ATTCGGCTACGCACAAGTTAAAGTTTCTGGTGAATCTGCACTGTTTAAAGATCTTGAGCTAACCCAAGATGTGTGGATGA
GCCACGGTGACAAAGTAGTAGAAATTCCTGCTGACTTCGTGAAAGTCGGTGAGACAGACACATGTCCGTACGCTGCGATG
GCGAACGAAGAGAAGAAGTACTACGGCGTACAGTTCCACCCAGAAGTAACGCACACGAAAGGCGGCCTACAAATGCTAGA
GAACTTCGTTCTTGGCGTATGTGGCTGTGAGCGTCTATGGACTTCTGAATCTATCATCGAAGACGCGGTTGCTCGTATTA
AAGAGCAAGTGGGTGACGACGAAGTTATCCTAGGTCTATCTGGTGGTGTTGATTCATCGGTAGTAGCGATGCTGGTTCAC
CGTGCAATCGGCGACAAGCTAACGTGTGTGTTCGTAGATAACGGTCTTCTTCGTTTAAACGAAGGTCAACAAGTAATGGA
TATGTTTGGCGACCAGTTTGGTCTGAACATCATCAAAGTTGATGCTGAAGATCGCTTCCTAAAAGCACTTGAAGGTAAGT
CGGATCCAGAAGAGAAGCGTAAGACAATCGGTCACGTATTCGTAGACGTATTTGATGAAGAGTCTAAGAAGCTGAAAAAC
GCGAAATGGCTAGCTCAAGGTACGATTTACCCAGACGTTATCGAATCTGCTGCATCTAAGACTGGTAAAGCGCACGTGAT
CAAATCACACCACAACGTGGGCGGTCTTCCAGATGACATGGAAATGGGTCTTGTTGAGCCACTACGTGAGCTGTTCAAAG
ATGAAGTTCGTAAGATCGGTCTAGAGCTTGGTCTTCCGTACAACATGCTTTACCGCCACCCATTCCCGGGGCCTGGTCTA
GGTGTTCGTGTTCTTGGCGAAATCAAGAAAGAGTACTGTGACTTGCTACGTCGTGCAGACGCTATCTTCATTGAAGAGCT
ACACGCTGCAGACCTATACAACAAAGTCTCTCAAGCGTTCACGGTATTCCTACCAGTTCGCTCTGTAGGTGTAATGGGCG
ATGGTCGTAAGTACGATTGGGTTGTTTCTCTACGTGCGGTAGAAACTATCGACTTTATGACTGCGCATTGGGCACACCTA
CCATACGACTTCCTAGGTAAGGTTTCTAACCGTATCATCAACGAAGTTGACGGTATTTCTCGCGTGGTTTACGACATTTC
TGGTAAGCCACCAGCGACAATCGAATGGGAATAA

Protein sequence :
MTKNIHDQRILILDFGSQYTQLVARRVREIGVYCELWSWDVEEADIREFNPDGIILSGGPESVTEDNSPRAPQYVFDSGV
PVLGVCYGMQTMAEQLGGKVAGSTEREFGYAQVKVSGESALFKDLELTQDVWMSHGDKVVEIPADFVKVGETDTCPYAAM
ANEEKKYYGVQFHPEVTHTKGGLQMLENFVLGVCGCERLWTSESIIEDAVARIKEQVGDDEVILGLSGGVDSSVVAMLVH
RAIGDKLTCVFVDNGLLRLNEGQQVMDMFGDQFGLNIIKVDAEDRFLKALEGKSDPEEKRKTIGHVFVDVFDEESKKLKN
AKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDDMEMGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGL
GVRVLGEIKKEYCDLLRRADAIFIEELHAADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHL
PYDFLGKVSNRIINEVDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-133 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-133 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-133 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-113 49