Gene Information

Name : Ser39006_3306 (Ser39006_3306)
Accession : YP_008523688.1
Strain : Serratia sp. ATCC 39006
Genome accession: NC_022268
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.58
Position : 3694667 - 3696280 bp
Length : 1614 bp
Strand : +
Note : TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase; KEGG: entE, enterobactin synthase subunit E; PFAM: AMP-dependent synthetase and ligase

DNA sequence : 
ATGAGTATTGAATTCACTCGCTGGCCGGCAGAGCGGGAACAACGCTACCGGGAACGTGGATATTGGGTCGATTTGCCACT
GTGCGATATTCTCGACCGTCAGGCCAACAACGATGCTATCGCCCTGATCTGCGGTGAACGGAGGTTCAGTTATCGCCAGC
TACACCAATCTGCCAATCGTCTGGCTTCCGCGCTTCTGCGCCGCGGGGTGCAACATGGGCAAACCGCACTGGTACAATTG
GGCAATATCGCCGAATTTTACCTGACCTATTTCGCGCTGTTACGCGCTGGCATAGTGCCGGTGAATGCCCTGTTCAACCA
TCAGCGCAGCGAACTGTGTGCCTATGCCGAACAGATCACCCCGGCATTACTGATCGCCGATCGCAGTCACAGCCTGTTTC
ACGATGACAGTTTCATTCAGGAATTACAGCAGCGTTACCCTTCCCTGCAACACATTATACTGCGTGGCGATAATGGCTCC
CCCGACGATCTGGCGATATTGCTACAAGAAGAAACGCCTATATTGCCAACCGCCCCTACGTCGGCTGACGATGTCGCCTT
TTTCCAGCTTTCCGGCGGGAGTACCGGCACACCCAAGCTGATCCCACGTACGCACAACGATTACTACTACAGCATTCGTG
CCAGCGTGGAGATCTGCCATTTTGATCACCATACCCGCTACCTGTGTGCCTTACCGGCAGCCCATAACTATCCGATGAGT
TCACCGGGAGCATTGGGCGTATTTTTCGCCGGCGGCAGCGTGGTGATGGCGAGTGATCCCAGTGCCACCAGCTGTTTTCC
ACTCATTGAGCGCCATCAAATTAATGTCACCGCGCTGGTGCCGCCAACCGTCACGTTATGGCTGGAAGCCATCGAACTAT
GCGGGAGCAACGCCTCGCTACACAGTCTCAGGCTACTGCAAGTCGGTGGCGCTCGCTTGAGTGAAGCGCTGGCCAGACGT
ATTCCGGCCTGCATCGGCTGCCAGTTACAGCAGGTTTTCGGCATGGCGGAAGGTCTGGTGAACTATACCCGGCTAGATGA
CGATGAAACTCATCTGTTCACTACGCAAGGGCGCCCTATCAGTGAGGATGACGAAGTGTGGGTCGCCGATGCCGAGGGAA
ATCCCTTACCATGCGGACAAGTGGGGCGACTGATGACCCGCGGCCCTTATACCTTCTGTGGTTACTATCGTAGCCCGCAC
TACAATCATCAAGTTTTTGATAAAAAAGGATTTTACCGTTCTGGCGATCTGGTTATCCAGACAGAAAACGGTTACTTGCA
GGTTGTTGGCCGGGAAAAGGACCAGATTAATCGTGGTGGAGAAAAAATTGCCGCTGAAGAGATTGAAAACCTGTTGTTAC
GCCACCCCGGGGTGATAAACGCCGCGCTGGTGGCAATTCCGGATCCATTGATGGGTGAAAAAAGCTGTGCCTTTATCGTC
GCCCGCGAAAACATCAAACCCGTGGCCCTACGTCGCCATCTGCGTGAACAAGGTATTGCCGACTATAAATTGCCGGATCG
TTTTGAACACATCTCGTCATTGCCCGAAACACCGGTAGGCAAAGTTGATAAACAGCGGTTGCGCCAGCTCGCACAGCAGC
GCACTCAACCTTAA

Protein sequence : 
MSIEFTRWPAEREQRYRERGYWVDLPLCDILDRQANNDAIALICGERRFSYRQLHQSANRLASALLRRGVQHGQTALVQL
GNIAEFYLTYFALLRAGIVPVNALFNHQRSELCAYAEQITPALLIADRSHSLFHDDSFIQELQQRYPSLQHIILRGDNGS
PDDLAILLQEETPILPTAPTSADDVAFFQLSGGSTGTPKLIPRTHNDYYYSIRASVEICHFDHHTRYLCALPAAHNYPMS
SPGALGVFFAGGSVVMASDPSATSCFPLIERHQINVTALVPPTVTLWLEAIELCGSNASLHSLRLLQVGGARLSEALARR
IPACIGCQLQQVFGMAEGLVNYTRLDDDETHLFTTQGRPISEDDEVWVADAEGNPLPCGQVGRLMTRGPYTFCGYYRSPH
YNHQVFDKKGFYRSGDLVIQTENGYLQVVGREKDQINRGGEKIAAEEIENLLLRHPGVINAALVAIPDPLMGEKSCAFIV
ARENIKPVALRRHLREQGIADYKLPDRFEHISSLPETPVGKVDKQRLRQLAQQRTQP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-85 43
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-85 43
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-85 42
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-85 42
ybtE CAA21394.1 - Virulence HPI Protein 2e-85 42
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-85 42
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-85 42
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-85 42
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-85 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ser39006_3306 YP_008523688.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 1e-170 67
Ser39006_3306 YP_008523688.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 3e-107 47
Ser39006_3306 YP_008523688.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-87 42