Gene Information

Name : Ser39006_2915 (Ser39006_2915)
Accession : YP_008523297.1
Strain : Serratia sp. ATCC 39006
Genome accession: NC_022268
Putative virulence/resistance : Virulence
Product : type III secretion apparatus H+-transporting two-sector ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.14
Position : 3211777 - 3213159 bp
Length : 1383 bp
Strand : +
Note : SMART: AAA ATPase; TIGRFAM: type III secretion apparatus H+-transporting two-sector ATPase, ATPase, FliI/YscN family; KEGG: type III secretion apparatus H+-transporting two-sector ATPase; PFAM: H+transporting two-sector ATPase alpha/beta subunit central r

DNA sequence :
ATGATGAGTCAGGAAACCGTGCGACATCTCCGCTATCCGTTACTGGATAGCTGGCTAAGCCATCAACGGCAGCAGTTGGC
GCTGTATTCCCCGGTCAATTTGCAGGGGCGGATCGTTGGCATCAGTGGCATTTTGCTGGAGTCCAGTCTGCCCCGCGCCC
GCATAGGTGATCTGTGCCTGGTGAAACGCAATGATGCAACGCAGATCCTGGCGGAAATCGTTGGTTTCAGCGCGGAAAAC
ACCTTTCTCTCCGCGCTGGGCGCGTTGGACGGTATCGCGCAGGGCGCCGTGGTTACGCCGTTATACCAGCCACATTGCGT
ACATATCTCCGATGCGCTGTTTGGCAGTGTGCTGGATGGGTTTGGTCGCCCGCTGGAAGAAGGTGGCGCCAGTGCGTTTG
TCGAACCCGGTGACATTTCGGTTCATCCCACGCCAGTGTTGGGCGATGCTCCACCCCCTACGGAACGCCCGCGGATCAGC
CAACCGCTGCCCACCGGAATACGGGCCATCGACGGTTTACTGACTATCGGTCGCGGCCAGCGTGTCGGCATATTTGCCGG
GGCGGGCTGTGGAAAAACCACACTGCTGGCCGAGCTGGCGCGTAACACCCCCTGTGACGCCATTGTGTTCGGTTTGATTG
GAGAACGTGGCCGTGAATTACGTGAATTTCTTGATCACGAACTGGATGAGGAATTGCGCCGCCGTACCGTCCTGATCTGC
GCCACCTCAGACCGCAGCAGTATGGAACGCGCCCGGGCGGCTTTTACCGCCACGGCTATCGCGGAAGCCTTCCGCAGCGA
GGGAAAACAGGTGTTACTGATCCTTGATTCACTCACCCGCTTCGCCCGTGCTCAGCGCGAAATCGGCCTGGCGTTGGGTG
AACCGCAAGGTCGCGGCGGACTGCCACCGTCGGTGTATACCCTGTTGCCACGGCTGGTGGAACGCGCCGGGCAAACTCGC
CAAGGCGCTATTACCGCACTCTACTCGGTGCTGATTGAACAGGATTCGATGAACGACCCGGTGGCGGATGAAGTGCGATC
ACTGATTGATGGCCACATCGTACTGTCACGCCATCTGGCGGAACGTAATCACTATCCGGCCATCGACGTGCTGATGAGCC
TGAGCCGCATCATGAGTAATATCGTCGAAAAAACACATACCCGTGACGCCAGTACCGTGCGGCGGTTGATGGCAGCCTAT
AAACAGGTAGAAATGCTGATCAGGCTGGGAGAATACCAGCCAGGACACGATACCTTTACCGATGCCGCCGTGAACGCCAA
TGATGAGATTAATCATTTTTTGCAGCAGTCCATGCGCGAACCATTGTCATTTGAAGATATTCAGGCCCGATTAGCGGAGC
TCAGTACCCATGCCACCGTCTAG

Protein sequence :
MMSQETVRHLRYPLLDSWLSHQRQQLALYSPVNLQGRIVGISGILLESSLPRARIGDLCLVKRNDATQILAEIVGFSAEN
TFLSALGALDGIAQGAVVTPLYQPHCVHISDALFGSVLDGFGRPLEEGGASAFVEPGDISVHPTPVLGDAPPPTERPRIS
QPLPTGIRAIDGLLTIGRGQRVGIFAGAGCGKTTLLAELARNTPCDAIVFGLIGERGRELREFLDHELDEELRRRTVLIC
ATSDRSSMERARAAFTATAIAEAFRSEGKQVLLILDSLTRFARAQREIGLALGEPQGRGGLPPSVYTLLPRLVERAGQTR
QGAITALYSVLIEQDSMNDPVADEVRSLIDGHIVLSRHLAERNHYPAIDVLMSLSRIMSNIVEKTHTRDASTVRRLMAAY
KQVEMLIRLGEYQPGHDTFTDAAVNANDEINHFLQQSMREPLSFEDIQARLAELSTHATV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-154 78
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-144 70
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-144 69
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 4e-143 69
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-143 69
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-120 68
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 5e-119 67
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-126 66
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-129 66
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 6e-130 66
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-119 63
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-119 63
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-79 51
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-78 51
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 7e-79 51
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 9e-79 51
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-79 51
lscN AAO18044.1 LscN Virulence TTSS locus Protein 6e-91 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 6e-79 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-82 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-82 49
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 5e-86 48
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-84 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-84 47
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-85 47
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 6e-86 47
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-86 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 6e-86 47
escN AAC31513.1 L0034 Virulence LEE Protein 2e-82 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-82 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-82 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-81 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-82 46
escN CAI43874.1 EscN protein Virulence LEE Protein 3e-82 45
escN YP_003223475.1 translocator EscN Virulence LEE Protein 4e-82 45
escN AAC38383.1 EscN Virulence LEE Protein 2e-82 45
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-79 44
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-82 44
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 4e-82 44
escN AAK26715.1 EscN Virulence LEE Protein 2e-82 44
escN AAL57542.1 EscN Virulence LEE Protein 2e-82 44
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-79 44
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-79 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-67 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 6e-67 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-67 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-67 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 9e-66 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-64 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-63 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0390 Protein 1e-90 52
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0048 Protein 3e-93 51
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0515 Protein 5e-79 51
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0192 Protein 3e-93 50
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG2144 Protein 6e-89 47
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0812 Protein 9e-83 46
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG1254 Protein 8e-75 46
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0730 Protein 1e-82 45
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG1778 Protein 4e-67 44
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0555 Protein 2e-67 43
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG2459 Protein 2e-69 43
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG1008 Protein 2e-65 43
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG2331 Protein 1e-69 42
Ser39006_2915 YP_008523297.1 type III secretion apparatus H+-transporting two-sector ATPase VFG2499 Protein 2e-68 41