Gene Information

Name : Ser39006_1476 (Ser39006_1476)
Accession : YP_008521858.1
Strain : Serratia sp. ATCC 39006
Genome accession: NC_022268
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : 5.99.1.2
Position : 1634403 - 1636415 bp
Length : 2013 bp
Strand : +
Note : SMART: DNA topoisomerase I DNA-binding protein, DNA topoisomerase I ATP-binding protein, TOPRIM domain-containing protein; TIGRFAM: DNA topoisomerase III; KEGG: DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein, TOPRIM domain-c

DNA sequence :
ATGCGCCTTTTCCTTTGTGAAAAACCCTCCCAGGGGAGAGATATTGCGGCCGTTCTCGGTGCCACTAAACGAGGAACCGG
CTTTCTTCAGGGCCCCGGTGTTACTGTGACCTGGGCTGTCGGACATTTACTCGAAACCGCCTCTCCTGAGGCGTATGGCA
CTCAGTTTGCACGACCCTGGAACATCCATGCTCTGCCGGTATTACCGGCACAGTGGCAAATGGTAGTGAAAAAGGAGACG
GAAGATCAGTTTAAGGCCATCGCGAAATTACTTAAGCAGGTTGACGAAGTGGTGATTGCCACCGATGCCGACCGAGAAGG
CGAGGTCATTGCCCGGGAATTGCTGGACTTTTGCCAGTGGCGCGGCCCGGTAAACCGGCTCTGGTTATCTGCCCTGGATG
AACCGAGTATTCGCAACGGACTGAATAACATCAAACCCGGTAATGAGACGCTGGCGCTGTACTACGCGGGGTTAGGCCGT
GCCCGGGCAGACTGGCTGACGGGCATGAATCTTACCCGGCTCTATACGTTGAAGGCCCGTGAAAAAGGCTTTGACGGTGT
GCTGTCCGTGGGGCGGGTGCAAACACCGACGCTGGCACTGGTGGTGAATCGGGACAGAGAAATCGCCATTTTTGTCCCGA
AGCCTTACTGGCAGGTCAACGCGGCTCTCCAGGCGTGTGGGATGGCGTTTGTTGCCCGCTGGGTGCCCGCGAAGATGTAC
ACCGATGAGGAAAAACGCTGTGTTCATCAGGGCATTGCTCAGCAGGTGGCCCAGCTTTGCCGTCAGTCGGGTCAGGCCCA
GGTCATTGAGCAGGAGAAAAAGCGGGAGACGGAGGCCGCTCCGTTGGCGTTTTCATTAGGGGCCTTGCAGCAGGCCTGCG
GCAAACTGTGGGATATGTCGCCTCAGCAGGTGCTTGATACCGCCCAAAGTCTGTATGAGACCCATAAGGCCACAACCTAT
CCCCGTACCGACTGTGGTTTTCTGCCGGAGTCGATGCGTGAAGAGATCCCGCTGGTTCTTGCCGCACTGGCGAAAACTGA
CCCGTCCCTCACGACGACGATAGCGACTCTTGATCCCCGTTTTGTATCACGTATCTGGAACGACAAAAAAATCACGGCGC
ACCACGGGATCATCCCCACTAAGCATGCCAGCGACATGGGCAACATGAATGATGTGGAGAAACGGGTGTATGAGCTTATT
CGTCGGCATTATCTGGCCCAGTTCCTCCCACTGTATGAGCGAGACGTGACCCGTCTTGATCTCAGCATCGGGGGACAGCT
TTTCAGAACAACCGGACAGGTTGTGGTGGTGCCTGGCTGGAAAGTGCTGTTCAGTTCGGCGACTGACAGAAAAGGTAACG
CTCAGGGTGATGAGGACAATGCGCTGCCATCCCTCAACAAAGGCGATGTCTGTACTGTGACGGTGGCTGAGGTGAAGGAT
CTTAAGACGAAAGCGCCGCTGTATTTTACATTTGATACGTTGATTGCCGCGATGATGAACGCAGCATCTTACGTGACCGA
TTTGCAGTTGAAAAAAGTCCTGAAAGAGAATGCCGGGTTGGGGACGGAGGCTACCCGCGCCAGCATCATTGATACGCTGC
TTAAGCGAGGCTACATCGTCATGAATAGACGTTATCTGCGGGCGACCGAAGTGGCGATGGATCTGATGGATGCTTTGCCA
GCTCCGCTGAAAGAACCGGGCATGACGGCGCTGTGGGAACAGGCGCTGGATGAGGTGGCCGCGGGCCGCATGCGTCTTGA
AGACTTTATGGCCCGGCAGACAGGTTGGACACGGCAACTGGTTGCTCAGGGACTGGCACAGAATATGGTGATCCGTTTGC
CACCGACGCCAGTTTGTCCTCTCTGCGGCAGTAAAACCCGGTTGCGTCGTGGTGAGAAAAAGGCTTTTTACCGTTGTGAG
AAATATCCGTCCTGCAAAGGTGTGGTTAATGTCCCTGACCAGGTGAAGAGGAAATCGGCGAAGTCTACGTCTCGAAAGCC
AAAGCAGAATTAA

Protein sequence :
MRLFLCEKPSQGRDIAAVLGATKRGTGFLQGPGVTVTWAVGHLLETASPEAYGTQFARPWNIHALPVLPAQWQMVVKKET
EDQFKAIAKLLKQVDEVVIATDADREGEVIARELLDFCQWRGPVNRLWLSALDEPSIRNGLNNIKPGNETLALYYAGLGR
ARADWLTGMNLTRLYTLKAREKGFDGVLSVGRVQTPTLALVVNRDREIAIFVPKPYWQVNAALQACGMAFVARWVPAKMY
TDEEKRCVHQGIAQQVAQLCRQSGQAQVIEQEKKRETEAAPLAFSLGALQQACGKLWDMSPQQVLDTAQSLYETHKATTY
PRTDCGFLPESMREEIPLVLAALAKTDPSLTTTIATLDPRFVSRIWNDKKITAHHGIIPTKHASDMGNMNDVEKRVYELI
RRHYLAQFLPLYERDVTRLDLSIGGQLFRTTGQVVVVPGWKVLFSSATDRKGNAQGDEDNALPSLNKGDVCTVTVAEVKD
LKTKAPLYFTFDTLIAAMMNAASYVTDLQLKKVLKENAGLGTEATRASIIDTLLKRGYIVMNRRYLRATEVAMDLMDALP
APLKEPGMTALWEQALDEVAAGRMRLEDFMARQTGWTRQLVAQGLAQNMVIRLPPTPVCPLCGSKTRLRRGEKKAFYRCE
KYPSCKGVVNVPDQVKRKSAKSTSRKPKQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 0.0 61
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 0.0 61
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 0.0 61
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 0.0 56
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 2e-166 52
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 4e-178 51
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 2e-174 50
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-158 48
topB AAW83109.1 TopB Not tested GGI Protein 8e-117 41