Gene Information

Name : guaA (SIR_0775)
Accession : YP_008512714.1
Strain : Streptococcus intermedius B196
Genome accession: NC_022246
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 788873 - 790432 bp
Length : 1560 bp
Strand : +
Note : -

DNA sequence :
ATGACAATTACAACTGAATTGCAAGATGTTGAAAGAATCATTGTATTGGATTATGGCAGTCAATATAATCAACTCATCTC
ACGCCGTATACGCGAGATTGGTGTTTTTTCTGAACTAAAAAGTAATAAAATTACAGCTGCTGAAGTTCGTGAAATAAATC
CAGTCGGAATTATCCTGTCTGGTGGGCCAAATTCTGTTTATGAAGAAGGTTCATTTGATCTTGACCCTGAAATTTTGGAA
TTGGGCATTCCAATTTTAGGGATTTGTTATGGCATGCAGCTTTTAACTCACAAATTAGGCGGAAAAGTTGTACCCGCAGG
AAACGCTGGAAATCGTGAGTACGGTCAGTCAGAACTCATTCATACGGATTCGCAACTGTTTGCAAGCACTCCTGAACAAC
AAATTGTTCTTATGAGTCATGGAGACGCTGTTACAGAAATTCCTCAAGGGTTTGTACGAACCGGAACTTCTGCCGACTGT
CCATTTGCAGCTATTGAAAATACCTCCAAGAAAATCTACGGCATTCAGTTTCACCCTGAAGTGCGTCATTCTGAGTTTGG
CTACGATATCCTGCGTAACTTTGCTCTTGATATTTGTGGAGCCAAAGGCGACTGGTCTATGGATAATTTTATTGATATGC
AAATTAAGCAAATTCGAGAAACTGTTGGAGATAAACGCGTTCTTCTGGGTCTATCGGGTGGTGTCGATTCATCAGTTGTT
GGTGTTCTCCTTCAAAAAGCTATTGGAGACCAGCTTATCTGTATTTTTGTAGATCATGGCTTACTCCGTAAGGGAGAGGC
GGAGCAAGTTATGGATTCTCTTGGCGGGAAATTTGGTCTTAATATTATTAAAGCAGATGCTGCCAAGCGTTTCCTTGATA
AATTAGCTGGTGTATCTGATCCAGAACAAAAGCGTAAAATCATTGGTAATGAGTTTGTTTATGTTTTTGACGATGAAGCT
AGCAAGTTAAAAGATGTAAAATTCCTCGCACAAGGAACGCTTTATACTGACGTTATCGAATCTGGTACAGATACTGCTCA
AACTATCAAGTCTCACCATAATGTTGGTGGTCTGCCAGAAGACATGCAGTTTGAGCTGATTGAGCCTCTCAATACACTTT
ATAAAGACGAAGTTCGTGCGCTTGGTACAGAACTTGGTATGCCAGATGAAATTGTTTGGCGTCAGCCATTCCCGGGCCCA
GGACTTGCCATTCGTATTATGGGCGAGATTACCGAAGAAAAACTCACAACTGTTCGTGAATCTGATGCCATTCTTCGCGA
AGAAATCGTGAAAGCTGGACTCGATCGTGATATTTGGCAGTACTTCACTGTGAATACTGGTGTTCGTTCGGTAGGTGTCA
TGGGAGATGGTCGAACTTATGACTATACTATCGCAATTCGTGCTATTACTTCTATTGATGGAATGACTGCAGATTTTGCT
AAAATTCCTTGGGAAGTATTGCAAAAAATCTCTGTTCGTATCGTCAATGAAGTAGCTCATGTTAATCGTATTGTCTACGA
TATTACTAGCAAGCCACCAGCAACGGTTGAGTGGGAATGA

Protein sequence :
MTITTELQDVERIIVLDYGSQYNQLISRRIREIGVFSELKSNKITAAEVREINPVGIILSGGPNSVYEEGSFDLDPEILE
LGIPILGICYGMQLLTHKLGGKVVPAGNAGNREYGQSELIHTDSQLFASTPEQQIVLMSHGDAVTEIPQGFVRTGTSADC
PFAAIENTSKKIYGIQFHPEVRHSEFGYDILRNFALDICGAKGDWSMDNFIDMQIKQIRETVGDKRVLLGLSGGVDSSVV
GVLLQKAIGDQLICIFVDHGLLRKGEAEQVMDSLGGKFGLNIIKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEA
SKLKDVKFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDEIVWRQPFPGP
GLAIRIMGEITEEKLTTVRESDAILREEIVKAGLDRDIWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFA
KIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-164 69
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-164 69
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-164 69
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-115 52