Gene Information

Name : hsdM (SIR_0687)
Accession : YP_008512629.1
Strain : Streptococcus intermedius B196
Genome accession: NC_022246
Putative virulence/resistance : Unknown
Product : type I restriction-modification system, M subunit
Function : -
COG functional category : -
COG ID : -
EC number : 2.1.1.72
Position : 696575 - 698170 bp
Length : 1596 bp
Strand : +
Note : -

DNA sequence :
ATGTCACAAACACAAGAAATTACAAATAAAATATGGGCAATGGCCAATGAACTGCGCGGGAACATGGATGCTTCTGAGTA
TAAAAATTATATCTTGGCTTTTATGTTTTATCGCTATTTGTCCGAGCATCAGGAGCAATACCTGATTAACAATGCTATTT
TAGATCTAGAAGATAGTAAGACAATCAACCAACTGTATACAGAGCAGGCAACGGGTGAGGAATTGGCAGATTATTTGGAA
GATATTGCGTTTAGTTTAGGGTATGCGATTGCTCCTGAAGATACATGGCTCTCTCTATTGGCTCGCATTGAAAACAATGA
GGTTATCCCAAGCGATTATCAGACGATTTTTGATCATTTCAATGCTAATGCGGAACTGAACAAAGAAGCGGTGCAGGATT
TCCGTGGAGTTTTTAATGATATCAATCTGGGAGATACGCGTCTTGGTTCTTCTACCAATGATCGGGCAAAATCGCTCAAT
CGGATTGTCAAATTAGTGGATGATATTAACTATAAGAGCGATGACGGTAGAGATATTTTAGGGTTTATCTATGAAGAATT
AATCAAGAAGTTTGCGGCTTCAGCAGGGAAAAAAGGCGGAGAATTTTACACACCGCATGAAGTTAGTCAAATTCTAGCTA
AGATTGTCACGGATAAGGTTGAACAAACCGAGCGTACCTTTTCTGTATATGACCCAACCATGGGTTCGGGTTCTCTTTTG
CTGACAGTTGGGAATGAATTGCCAAATGGTCAAAAGCCTGGAGCAATTAAGTATTTTGGGCAGGAGCTTAATACAACGAC
CTATAACTTGGCTAGGATGAATCTGATGATGCACGGTGTTACTTATAGTAACATGAATCTGAGCAATGCTGACACCTTGG
AAAGTGATTGGCCGGACGGACCGGACGAAAAAGGGGTTGACCATCCCCGCAGCTTCGATGCAGTAGTAGCCAACCCCCCC
TATTCTGCTAAATGGGACAATGCTGACAACAAGCTAAAAGACCCGCGCTTTTCAGAATATGGGAAATTAGCTCCTGCTTC
TAAGGCGGATTTTGCCTTTATTCTCCACAGTGTCTACCATCTGAATGATACAGGTACCATGGCCATTGTTTTGCCGCACG
GCGTGCTCTTTCGGGGATCTGCTGAATTAAAAATCCGTCAGACGCTGGTTGAAAAGAATTACTTGGATACCGTTATTGGT
CTGCCAGCCAATCTCTTTTATGGAACAAGCATTCCCACAACTGTTCTTGTTTTCAGAAAAAATAAAGAAAATCGAGACAT
TCTTTTCATTGATGCCAGTAAAGATTTTGATAAGGGAAAGAATCAAAACACCTTAAACAATACTCACATTGAAAAAATTA
TTGAAACTTTCCGAAATCGTCAAGATGTGAACAAATATGCTCGACTAGTTTCATTTGAAGAGATTAAAGAGAATGATTTT
AATCTAAACATTCCTCGATATGTTGATACTTTCGAAGAGGAAGAGGAGATAGATCTGGATGAGATAACCCGCCTTATCGC
TCAAGATGAAGCGGAAATAGCAGAATTAGAAGCCCTTATCGCAGACCAATTACGTCAGTTGGGAGTGGAGATGTAA

Protein sequence :
MSQTQEITNKIWAMANELRGNMDASEYKNYILAFMFYRYLSEHQEQYLINNAILDLEDSKTINQLYTEQATGEELADYLE
DIAFSLGYAIAPEDTWLSLLARIENNEVIPSDYQTIFDHFNANAELNKEAVQDFRGVFNDINLGDTRLGSSTNDRAKSLN
RIVKLVDDINYKSDDGRDILGFIYEELIKKFAASAGKKGGEFYTPHEVSQILAKIVTDKVEQTERTFSVYDPTMGSGSLL
LTVGNELPNGQKPGAIKYFGQELNTTTYNLARMNLMMHGVTYSNMNLSNADTLESDWPDGPDEKGVDHPRSFDAVVANPP
YSAKWDNADNKLKDPRFSEYGKLAPASKADFAFILHSVYHLNDTGTMAIVLPHGVLFRGSAELKIRQTLVEKNYLDTVIG
LPANLFYGTSIPTTVLVFRKNKENRDILFIDASKDFDKGKNQNTLNNTHIEKIIETFRNRQDVNKYARLVSFEEIKENDF
NLNIPRYVDTFEEEEEIDLDEITRLIAQDEAEIAELEALIADQLRQLGVEM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM1 YP_185366.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 8e-96 51
hsdM YP_001331432.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥á Protein 8e-96 51
hsdM YP_493119.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 8e-96 51
SAKOR_01757 YP_008491945.1 Type I restriction-modification system methylation subunit Not tested vSa¥â Protein 4e-96 51
hsdM YP_001332734.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥â Protein 8e-96 51
hsdM YP_494443.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 8e-96 51
SAR1899 YP_041281.1 type I restriction modification system modification protein Not tested vSa¥â Protein 8e-95 50
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 1e-93 50
hsdM2 YP_186690.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 1e-95 50
hsdM NP_646568.1 hypothetical protein Not tested vSa¥â Protein 3e-95 50
ORF6 BAC22943.1 - Not tested etd PI Protein 8e-96 50
SAKOR_00415 YP_008490599.1 Type I restriction-modification system methylation subunit Not tested vSa¥á Protein 1e-95 50
SAV1808 NP_372332.1 type I restriction enzyme EcoR124II M protein Not tested vSa¥â Protein 3e-95 50
SA1626 NP_374915.1 hypothetical protein Not tested vSa¥â Protein 3e-95 50
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 2e-95 50
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 2e-95 50
hsdM NP_373642.1 type I site-specific deoxyribonuclease LldI subunit HsdM Not tested vSa¥á Protein 2e-95 50
hsdM NP_645209.1 type I site-specific deoxyribonuclease LldI chain hsdM Not tested vSa¥á Protein 2e-95 50
hsdM NP_370955.1 type I site-specific deoxyribonuclease LldI chain Not tested vSa¥á Protein 4e-95 50
SAR0433 YP_039884.1 type I restriction enzyme modification protein Not tested vSa¥á Protein 6e-96 50
SAS0394 YP_042520.1 restriction enzyme modification protein Not tested vSa¥á Protein 1e-95 50
SAS1732 YP_043848.1 type I restriction enzyme modification protein Not tested vSa¥â Protein 3e-95 50