Gene Information

Name : pyk (SIR_0535)
Accession : YP_008512478.1
Strain : Streptococcus intermedius B196
Genome accession: NC_022246
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 536354 - 537856 bp
Length : 1503 bp
Strand : +
Note : -

DNA sequence :
ATGAATAAACGTGTAAAAATCGTTGCAACTTTAGGTCCTGCGGTAGAAATCCGTGGTGGTAAAAAATTTGGTGAAGATGG
ATATTGGAGTGAAAAACTTGATGTTGAATCATCTGCACAAAATATCGCTAAATTGATTGAGGCCGGAGCAAACACTTTCC
GTTTCAACTTCTCACATGGTGACCACGCAGAACAAGGTGACCGTATGGCTACTGTTCATCGTGCCGAAGAAATTGCTGGT
CAAAAAGTTGGTTATCTTCTTGACACAAAAGGTCCTGAAATTCGTACAGAATTATTTGAAGGCGACGCTAAAGAATACTC
TTACAAAACGGGTGAAAAGATCCGTGTTGCAACTAAACAAGGTATTAAATCTACTCGCGAAGTTATCGCTTTGAATGTTG
CAGGTGGCCTTGATATTTATGACGATGTTGAAGTTGGAAAACAAGTTCTTGTTGACGATGGAAAACTTGGCCTTCGTGTT
ATTGCAAAAGATCCTGCTACACGTGAATTTGAAGTAGAAGTTGAAAACGACGGTGTTATCGCTAAACAAAAAGGTGTTAA
TATTCCAAATACAAAAATTCCTTTCCCAGCACTTGCTGAACGTGATAATGACGATATTCGCTTTGGTTTAGAACAAGGAA
TCAACTTCATTGCTATTTCATTTGTACGTACTGCAAAGGATGTCAATGAAGTTCGTGCAATCTGTGAAGAGACTGGTAAT
GGACATGTGAAATTGTTTGCTAAAATCGAAAATCAACAAGGTATCGAAAACTTGGATGAAATCATCGAAGCTGCTGACGG
TATCATGATTGCTCGTGGTGACATGGGTATCGAAGTACCATTTGAAATGGTTCCAGTTTACCAAAAAATGATTATCACAA
AAGTCAATGCTGCTGGTAAAATTGCTATTACAGCAACAAATATGCTTGAAACAATGACTGAAAAACCACGTGCTACTCGT
TCAGAAGTATCAGATGTGTTCAATGCTGTTATTGATGGAACAGATGCGACAATGCTTTCAGGTGAATCTGCAAATGGTAA
ATATCCACTTGAATCTGTAACGACAATGGCAACAATTGATAAAAATGCTCAAACTCTCTTGAATGAATATGGACGTTTGT
CATCAGTTGACTATGCTCGTAGCTCTAAGACAGAGGTTGTTGCTTCAGCTGTTAAAGATGCTACAAACTCAATGGACATC
AAATTGGTTGTGACAATTACTGAAACAGGTAACACTGCACGTTTGATTTCTAAGTATCGTCCTGATACTGATATTTTAGC
AGTAACATTTGATGAATTGACTCAACGTTCATTGATGTTGAATTGGGGTGTCATTCCAGTTGTAACTGAAAAACCTGCAT
CAACTGATGATATGTTTGAAGTTGCTGAAAAAGTTGCTCTTGCAAGTGGTCTTGTGGAATCTGGCGACAATATTGTGATT
GTGGCTGGTGTACCAGTTGGAACTGGTGGAACAAACACTATGCGTATTCGTACAGTACGTTAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWSEKLDVESSAQNIAKLIEAGANTFRFNFSHGDHAEQGDRMATVHRAEEIAG
QKVGYLLDTKGPEIRTELFEGDAKEYSYKTGEKIRVATKQGIKSTREVIALNVAGGLDIYDDVEVGKQVLVDDGKLGLRV
IAKDPATREFEVEVENDGVIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGN
GHVKLFAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKIAITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQTLLNEYGRLSSVDYARSSKTEVVASAVKDATNSMDI
KLVVTITETGNTARLISKYRPDTDILAVTFDELTQRSLMLNWGVIPVVTEKPASTDDMFEVAEKVALASGLVESGDNIVI
VAGVPVGTGGTNTMRIRTVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-82 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-83 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-82 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-82 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_008512478.1 pyruvate kinase VFG0479 Protein 5e-83 44