Gene Information

Name : clpL (SIR_1659)
Accession : YP_008513577.1
Strain : Streptococcus intermedius B196
Genome accession: NC_022246
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpL
Function : -
COG functional category : -
COG ID : -
EC number : 3.4.21.92
Position : 1751506 - 1753635 bp
Length : 2130 bp
Strand : -
Note : -

DNA sequence :
ATGAACAATAACTATAATAACTTTGATAATATGGATGATCTTTTCAATCAATTGATGGGAAGAATGGGTGGTTTTAACAG
TGAAAATCGGCGTTATCTTATCAATGGACGTGAAGTGACACCAGAAGAATTTGCACAATATCGTGCAACAGGTAAATTAC
CGAAGCAAGTAGCGGAAGGTCAGGCATCACAAATGCAAGGACAAGCAGGTGAGCTTAAACAAGATGGTATTTTAATGAAG
TTAGGGCGTAATTTGACAGAAGAAGCACGTCAAGATATGTTAGATCCTGTTATTGGACGCAATAAGGAAATTCAAGAAAC
GGCTGAAATTCTTTCTCGGCGGACGAAAAACAATCCAGTATTAGTCGGAGACGCTGGAGTTGGTAAGACTGCAGTTGTTG
AAGGTTTAGCGCAAGCGATTGTTAATGGAGATGTTCCTGCAGCCATTAAGAATAAAGAGATTGTTTCTATTGATATTTCT
GGTTTAGAAGCAGGGACACAGTATCGTGGTAGTTTTGAAGAAAATATTCAAAATTTAGTATCTGAAGTGAAAGAGGCTGG
CAATATCATTCTCTTCTTTGATGAAATTCATCAAATTCTCGGCGCTGGAAGCACAGGCGGTGATAGTGGATCAAAAGGTC
TAGCAGATATTTTGAAACCGGCTTTATCTCGTGGTGAACTGACAGTTATCGGTGCGACGACTCAGGATGAATATCGAAAT
ACCATTTTGAAGAATGCAGCTCTAGCTCGTCGCTTCAATGAAGTAAAAGTCAATGCCCCATCTGCAGAAGATACTTACAA
GATTTTGCAAGGAATTCGTGATTTATACGAAAAACACCACAATGTCATCTTGCCAGATGACGTGTTAAAAGCTGCCGTGG
ACTTCTCTATTCAATATATTCCACAACGCAGCTTGCCGGATAAAGCGATTGACCTGGTGGATGTGACAGCGGCTCATTTA
GCAGCTCAACATCCTGTTACAGATGTGCATACAGTGGAACGTGAAATTGCAGAGCAAAAGAAAAAGCAAGAAGCTGCGGT
TGAAAAAGAAGACTTTGAAACTGCTTTGAATGCCAAGATGCGTATTGAAGAGCTAGAAAAAAAGATTGAAAATCATACGG
AAGACATGAAGGTGACTGCAACTGTCAATGATGTAGCAGAATCTGTAGAACGTATGACGGGCATTCCTGTTTCCCAAATG
GGGACTAGTGATATTGAACGGTTGAAAGAGATGAATGCGCGATTGAAGACAAAAGTCATTGGACAAAACGAAGCAGTTGA
AGCAGTGGCGCGCGCTATTCGTCGGAATCGTGCAGGTTTTGATGAAGGAAATCGTCCGATTGGTAGCTTTCTCTTTGTTG
GCCCAACTGGTGTTGGAAAAACAGAGCTAGCGAAGCAATTAGCGCTTGATATGTTTGGTACTAAAGAAGCCATTATCCGT
TTGGACATGTCTGAATACTCTGACCGCACAGCTGTGTCGAAATTGATTGGTACAACAGCTGGTTATGTGGGGTATGATGA
CAATAGCAACACGTTGACAGAACGTGTTCGTCGGAATCCTTACTCTATCATCTTGCTGGACGAAATTGAAAAAGCCGATC
CACAAGTCATCACATTGTTACTACAAGTTTTGGACGATGGACGTCTGACAGATGGACAAGGAAATACTGTCAACTTTAAG
AACACAGTTATTATTGCTACATCAAATGCTGGATTTGGGTATGAAAGCTTTACTGGTGATGAGGAAAAGGATAGGAAGAT
TATGGATCGCTTAAAACCATACTTCCGCCCAGAATTCTTGAATCGCTTCAATGCAGTCATTGAATTCTCTCATCTTGGTA
AAGAAGATTTAGCCGAAATCGTCGACTTGATGTTGGATGAGGTCAACCAAACACTTGCTAAGAAAGACATTATGCTAACA
GTAACAGATGCGGCCAAACATTATCTAGCAGAAGAGGGATATGATGAAGTTATGGGTGTTCGTCCGCTTCGTCGTGTGAT
TGAGCAACAAATCCGTGATAAGGTAACAGACTATCATCTTGATCATTTAGATGCGAAACATCTTCTTGCATATTTGAAAG
ATGATGAATTAGTTATCGAAGAAGCGAAAGAGCATCAAACGAAAAAATAA

Protein sequence :
MNNNYNNFDNMDDLFNQLMGRMGGFNSENRRYLINGREVTPEEFAQYRATGKLPKQVAEGQASQMQGQAGELKQDGILMK
LGRNLTEEARQDMLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIVSIDIS
GLEAGTQYRGSFEENIQNLVSEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRN
TILKNAALARRFNEVKVNAPSAEDTYKILQGIRDLYEKHHNVILPDDVLKAAVDFSIQYIPQRSLPDKAIDLVDVTAAHL
AAQHPVTDVHTVEREIAEQKKKQEAAVEKEDFETALNAKMRIEELEKKIENHTEDMKVTATVNDVAESVERMTGIPVSQM
GTSDIERLKEMNARLKTKVIGQNEAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKEAIIR
LDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFK
NTVIIATSNAGFGYESFTGDEEKDRKIMDRLKPYFRPEFLNRFNAVIEFSHLGKEDLAEIVDLMLDEVNQTLAKKDIMLT
VTDAAKHYLAEEGYDEVMGVRPLRRVIEQQIRDKVTDYHLDHLDAKHLLAYLKDDELVIEEAKEHQTKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-127 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpL YP_008513577.1 ATP-dependent Clp protease ATP-binding subunit ClpL VFG0080 Protein 6e-137 48
clpL YP_008513577.1 ATP-dependent Clp protease ATP-binding subunit ClpL VFG0079 Protein 3e-132 45