Gene Information

Name : clpC (SIR_0133)
Accession : YP_008512098.1
Strain : Streptococcus intermedius B196
Genome accession: NC_022246
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 132979 - 135408 bp
Length : 2430 bp
Strand : +
Note : -

DNA sequence :
ATGAAATATTCAAAAGCTTTGACAGAAAGTATTGAATCAGCACAGTTATTAGCAAGTCATTTTGAAACGGATTATTTAGA
GTCTTGGCAGCTGTTGATTGCTATGGCAAATAATCCTTATAGTGTTGCTGGTTCAGTTTTAAATGATTACCCACTTGAAA
TTGATGATTTTGAAAAGGCAGCTTTTCATATCACGGGGAAAGTCTATCAACAAGAGGGAGACTTTACTATTTGGCCGTTT
TCTTATCGCATGAAAGTGCTATTTTTGACTGCTGAACAAATTGCAGGGGCGGTTCATGCTAATAATCTTGGGACAGAGCA
TATATTGCTAGCTATGTTATTTGACCGAGGAAGCTTGGCAGCGCGTATTCTTGAATTTATTGGTTTTAGTTACGAAGATA
AAGAAGGCGTTTTGCGCATGACAGATCTGCGGAAAAATTTAGAGCATAAGGCCAGCTGGAATAAAGAGGATTTAAAGGCT
ATTCGTCACCTAAATAAAAGTGCTGCAGCAACAAGACAAACGATGGCTAATATGATGGGAATGCCTCCTGCAACCAGTGG
CGGACTAGAAGATTATACTCGTGATCTAACTGAAATGGCTCATATGGGCCTTTTAGAACCGGTCATTGGGCGGGATAAAG
AGATTTCTCGCATACTTCAGATTTTAAGTCGTAAGACAAAAAACAATCCGGTTTTGGTAGGAGATGCAGGAGTTGGGAAG
ACAGCATTAGCTCTGGGTTTGGCGCAACGTGTGGCAGATGGTCAAGTTCCAAATGAGCTTGCAAAGATGAGAGTTTTAGA
GCTAGATTTAATGAATGTGGTGGCTGGAACTCGTTTTCGTGGTGATTTTGAAGAACGGATGAACAATATTATCAATGATA
TTGAAGCAGATGGGCATGTTATTCTCTTCATTGATGAGCTTCATACCATTATGGGGTCTGGCAGCGGGATTGACTCGACA
TTAGATGCAGCAAATATTCTCAAGCCGGCTTTGGCTAAAGGAACGCTCAGAACGATCGGTGCAACAACACAAGAAGAGTA
CCAAAAATATATCGAAAAAGATGCAGCTCTTTCACGAAGATTTGCCAAGGTTACTATTGAAGAACCAACGGTAGCTGACA
GCATTGCTATTTTACAGGGACTCAAGAAAAGTTATGAAGATCACCACAAGGTCGTGATTACGGATTCGGCAATTGAGACG
GCTGTTAAGTATGCGCATCGTTACCTGACTAGTAAACATCTACCTGACTCAGCGATTGACTTGCTAGACGAAGCTGCTGC
AAGGGTACAAAATAAAAGCCCGCAAAATCACGTAAAAGCAGAATTGAGTGCAGCAGATGAGGCTTTAATGGCAGGCGATT
GGAACAAAGTTGATACGTTGTTGGAGAAAGAGAGTCAGCCAATTGTTTATAAATTAAGGGTGAAAGACGAGGATGTTTTA
GCAACACTCAGCAGTTTATCAGGTATTCCTGTGCAAAAGTTGACACAAACAGATGCGAAGAAATACCTCAATTTAGAAAA
GGAACTGCACAAGCGGGTCATTGGACAAAATGAAGCAATTTCTGCTATTAGTCGAGCGATTCGGCGCAATCAATCCGGTA
TCCGCACTAGCAAGCGTCCAATTGGCTCCTTTCTGTTCTTAGGGCCAACTGGGGTCGGAAAAACTGAGCTAGCTAAGGCT
TTGGCAGAAGTTCTCTTTGATGACGAAACAGCGTTAATTCGTTTTGATATGTCCGAATACATGGAGAAATTTGCTGCTAG
TCGTCTCAATGGAGCACCTCCAGGCTATGTTGGTTATGAAGAAGGGGGAGAATTAACTGAAAAGGTGCGTAATCGTCCTT
ACTCTGTGCTCCTCTTTGATGAAGTGGAAAAAGCTCATCCTGATATTTTCAATGTGCTGCTCCAAGTCCTAGATGACGGG
GTTCTGACGGATAGCAAGGGCCGTAAGGTAGATTTTTCCAATACTATTATCATTATGACCAGCAATCTTGGTGCGACAAG
TTTACGGGACGATAAGACGGTTGGGTTCGGAGCAAGAGATGTTCGCTTTGATCATGAAAATATGGAAAAACGAATGATGG
AAGAGCTAAAGAAAGCTTATCGTCCAGAATTTATTAACCGAATTGATGAAAAGGTTGTTTTTCACAGTTTGACTAGCGAA
GACATGCAGGAAGTGGTGAAAATTATGGTGCAACCGCTCATTTCTAGTCTTGCAGAAAAAGGAATTAAACTCAAATTCCA
ACCGAGTGCTTTGAAGCTTCTAGCTCAAGAGGGCTATGATCCTGAAATGGGAGCTCGTCCATTGCGTCGAATTCTACAAA
CTCGAGTGGAAGACCATTTATCAGAATTACTTTTATCAGGTGAGTTAAAAATGGGGCAAAGCTTGAAAGTCGGTGTCAAG
GCTGGAAAATTGAAGTTTGAAGTGCTCTGA

Protein sequence :
MKYSKALTESIESAQLLASHFETDYLESWQLLIAMANNPYSVAGSVLNDYPLEIDDFEKAAFHITGKVYQQEGDFTIWPF
SYRMKVLFLTAEQIAGAVHANNLGTEHILLAMLFDRGSLAARILEFIGFSYEDKEGVLRMTDLRKNLEHKASWNKEDLKA
IRHLNKSAAATRQTMANMMGMPPATSGGLEDYTRDLTEMAHMGLLEPVIGRDKEISRILQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVADGQVPNELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEADGHVILFIDELHTIMGSGSGIDST
LDAANILKPALAKGTLRTIGATTQEEYQKYIEKDAALSRRFAKVTIEEPTVADSIAILQGLKKSYEDHHKVVITDSAIET
AVKYAHRYLTSKHLPDSAIDLLDEAAARVQNKSPQNHVKAELSAADEALMAGDWNKVDTLLEKESQPIVYKLRVKDEDVL
ATLSSLSGIPVQKLTQTDAKKYLNLEKELHKRVIGQNEAISAISRAIRRNQSGIRTSKRPIGSFLFLGPTGVGKTELAKA
LAEVLFDDETALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
VLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDVRFDHENMEKRMMEELKKAYRPEFINRIDEKVVFHSLTSE
DMQEVVKIMVQPLISSLAEKGIKLKFQPSALKLLAQEGYDPEMGARPLRRILQTRVEDHLSELLLSGELKMGQSLKVGVK
AGKLKFEVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-141 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_008512098.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0079 Protein 1e-165 47
clpC YP_008512098.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0080 Protein 4e-125 45