Gene Information

Name : pyk (SANR_0831)
Accession : YP_008500566.1
Strain : Streptococcus anginosus C238
Genome accession: NC_022239
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 856846 - 858348 bp
Length : 1503 bp
Strand : +
Note : -

DNA sequence :
ATGAATAAACGTGTAAAAATCGTTGCAACTTTAGGTCCTGCGGTAGAAATCCGTGGTGGTAAAAGATTCGGTGAAGACGG
ATATTGGGGTGAAAAGCTTGACGTTGAAGCATCAGCGCAAAATATCGCTAAATTGATCGAAGCTGGAGCTAACACTTTCC
GTTTCAACTTCTCACATGGTGACCACGCAGAGCAAGGTGACCGTATGGCTACTGTTCATCGTGCTGAAGAAATTGCTGGT
CAAAAAGTTGGTTACCTTCTTGACACTAAAGGTCCTGAAATCCGTACAGAATTATTTGAAGGCGATGCTAAAGAATATTC
TTACAAAACAGGTGAAAAAATCCGTGTTGCAACTAAACAAGGTATCAAATCAACTCGTGAAGTTATCGCATTGAATGTTG
CTGGTGCACTTGATATCTATGACGATGTTGAAGTTGGAAAACAAGTTCTTGTTGATGACGGTAAACTTGGTCTTCGCGTG
ATTGCAAAAGATCCTGCTACACGTGAATTTGAAGTAGAAGTTGAAAACGACGGTATTATCGCTAAACAAAAAGGTGTTAA
TATTCCAAATACAAAAATTCCTTTCCCAGCACTTGCTGAACGTGACAATGACGATATTCGTTTTGGTCTTGAACAAGGAA
TCAACTTTATCGCTATTTCATTCGTACGTACTGCAAAAGACGTCAACGAAGTTCGTGCAATCTGTGAAGAAACCGGTAAT
GGACATGTGAAATTGTTCGCTAAAATCGAAAACCAACAAGGTATCGAAAACTTGGATGAAATCCTTGAAGTAGCGGACGG
TATCATGATTGCTCGTGGTGATATGGGTATTGAAGTACCATTTGAAATGGTTCCAGTTTACCAAAAAATGATTATCACAA
AAGTCAATGCAGTTGGTAAAATTGCGATCACAGCAACAAACATGCTTGAAACAATGACTGAAAAACCACGTGCGACTCGT
TCAGAAGTATCAGACGTATTTAACGCTGTTATTGACGGAACAGATGCAACAATGCTTTCAGGTGAATCTGCAAATGGTAA
ATACCCACTTGAATCTGTAACAACAATGGCTACAATTGATAAAAACGCTCAAACTCTATTGAACGAGTATGGACGCTTGT
CATCAGTTGATTACGCACGTAGTTCTAAGACAGAAGTTGTGGCTTCAGCTGTTAAAGATGCTACAAACTCAATGGACATC
AAATTGGTTGTAACAATGACTGAATCAGGAAATACAGCTCGTTTGATTTCTAAATATCGTCCAGATGCTGACATCTTGGC
AATTACATTTGATGAATTGACACAACGTTCATTGATGTTGAACTGGGGTGTTATTCCAGTAGTAACTGAAAAACCTGCAT
CTACTGATGATATGTTTGAAGTTGCTGAAAAAGTTGCTCTTGAAAGTGGTCTTGTGGAATCTGGCGACAATATTGTGATT
GTAGCTGGTGTTCCGGTCGGAACTGGTGGAACAAACACAATGCGTATCCGTACAGTCCGTTAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKRFGEDGYWGEKLDVEASAQNIAKLIEAGANTFRFNFSHGDHAEQGDRMATVHRAEEIAG
QKVGYLLDTKGPEIRTELFEGDAKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGKQVLVDDGKLGLRV
IAKDPATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGN
GHVKLFAKIENQQGIENLDEILEVADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAVGKIAITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQTLLNEYGRLSSVDYARSSKTEVVASAVKDATNSMDI
KLVVTMTESGNTARLISKYRPDADILAITFDELTQRSLMLNWGVIPVVTEKPASTDDMFEVAEKVALESGLVESGDNIVI
VAGVPVGTGGTNTMRIRTVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-82 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-83 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-83 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-83 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_008500566.1 pyruvate kinase VFG0479 Protein 3e-83 44