Gene Information

Name : pyk (SCI_0715)
Accession : YP_008498664.1
Strain : Streptococcus constellatus C1050
Genome accession: NC_022238
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 728219 - 729721 bp
Length : 1503 bp
Strand : +
Note : -

DNA sequence :
ATGAATAAACGTGTAAAAATCGTTGCAACTTTAGGTCCTGCGGTAGAAATCCGTGGTGGTAAAAAATTTGGTGAAGATGG
CTATTGGAGCGAAAAATTAGATGTTGAAGCATCGGCTCAAAATATTGCAAAATTAATCCAAGCTGGTGCAAATACATTCC
GTTTCAACTTCTCGCATGGTGATCATGCAGAACAAGGTGATCGTATGGCTACTGTGCACCGTGCAGAAGAAATTGCTGGT
CAAAAAGTTGGTTATCTTCTTGATACAAAAGGACCTGAAATTCGTACAGAATTATTTGAAGGTGACGCTAAAGAATACTC
TTACAAAACGGGTGAACAAATCCGTGTTGCAACGAAACAAGGTATCAAATCAACTCGCGAAGTTATTGCTTTGAACGTAG
CAGGTGCACTTGACATCTTTGATGACGTTGAAGTTGGGAAACAAGTTCTTGTTGATGATGGTAAACTTGGTCTGCGCGTT
ATTGCAAAAGATCCTGCTACACGTGAATTTGAAGTAGAGGTTGAAAATGATGGAATTATCGCAAAACAAAAAGGTGTGAA
TATTCCAAATACAAAAATTCCTTTCCCAGCGCTTGCTGAACGCGACAATGATGATATTCGTTTCGGTTTGGAACAAGGAA
TCAACTTTATCGCTATTTCATTCGTACGTACTGCAAAAGATGTTAATGAAGTTCGTGCAATCTGTGAAGAAACTGGTAAT
GGACATGTGAAATTGTTCGCTAAAATCGAAAACCAACAAGGTATTGAAAACTTGGATGAAATCCTTGAAGTAGCTGATGG
TATCATGATTGCTCGTGGTGACATGGGTATTGAAGTTCCATTTGAAATGGTTCCAGTTTACCAAAAAATGATTATCACAA
AAGTCAATGCAGCTGGTAAAATTGCGATTACAGCAACAAACATGCTTGAAACAATGACTGAAAAACCGCGTGCTACTCGT
TCAGAAGTATCAGACGTGTTTAACGCTGTTATTGACGGAACAGATGCAACAATGCTTTCAGGTGAATCTGCAAATGGTAA
ATACCCACTTGAATCTGTAACAACTATGGCTACAATTGATAAAAATGCTCAAACTCTATTGAATGAATATGGACGTTTGT
CATCAGTTGACTACGCTCGTAGTTCTAAAACAGAAGTTGTTGCTTCAGCAGTGAAAGATGCTACAAACTCAATGGATATC
AAATTGGTCGTTACAATCACTGAAACAGGTAACACTGCACGATTGATTTCTAAATACCGTCCTGACGCTGATATCTTAGC
AGTAACATTTGATGAATTGACACAACGCTCATTGATGTTAAACTGGGGTGTTATTCCAGTTGTAACTGAAAAAACTGCTT
CTACTGATGACATGTTTGAAGTTGCAGAAAAAGTTGCTCTTTCAACAGGATTAGTAGAATCAGGTGACAACATTGTGATT
GTAGCCGGTGTTCCAGTTGGAACCGGTGGAACAAACACTATGCGTATCCGCACAGTTCGTTAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWSEKLDVEASAQNIAKLIQAGANTFRFNFSHGDHAEQGDRMATVHRAEEIAG
QKVGYLLDTKGPEIRTELFEGDAKEYSYKTGEQIRVATKQGIKSTREVIALNVAGALDIFDDVEVGKQVLVDDGKLGLRV
IAKDPATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGN
GHVKLFAKIENQQGIENLDEILEVADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKIAITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQTLLNEYGRLSSVDYARSSKTEVVASAVKDATNSMDI
KLVVTITETGNTARLISKYRPDADILAVTFDELTQRSLMLNWGVIPVVTEKTASTDDMFEVAEKVALSTGLVESGDNIVI
VAGVPVGTGGTNTMRIRTVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-82 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-83 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-83 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-83 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_008498664.1 pyruvate kinase VFG0479 Protein 3e-83 44