Gene Information

Name : pyk (SII_0517)
Accession : YP_008496699.1
Strain : Streptococcus intermedius C270
Genome accession: NC_022237
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 524033 - 525535 bp
Length : 1503 bp
Strand : +
Note : -

DNA sequence :
ATGAATAAACGTGTAAAAATCGTTGCAACTTTAGGTCCTGCGGTAGAAATCCGTGGTGGTAAAAAATTTGGTGAAGATGG
ATATTGGAGTGAAAAACTTGATGTTGAATCATCTGCACAAAATATCGCTAAATTGATTGAGGCCGGAGCAAACACTTTCC
GTTTTAACTTCTCACATGGTGACCACGCAGAACAAGGTGACCGTATGGCTACTGTTCATCGTGCTGAAGAAATTGCTGGT
CAAAAAGTTGGTTATCTTCTTGACACAAAAGGTCCTGAAATTCGTACAGAATTATTTGAAGGCGACGCTAAAGAATACTC
TTACAAAACGGGTGAAAAGATTCGTGTTGCAACTAAACAAGGTATTAAATCCACTCGTGAAATTATCGCTTTGAATGTTG
CTGGTGCACTTGATATCTATGATGATGTTGAAGTTGGAAAACAAGTTCTTGTTGACGATGGAAAACTTGGCCTTCGTGTT
ATTGCAAAAGATCCTGCTACACGTGAATTTGAAGTAGAAGTTGAAAACGACGGTATTATCGCTAAACAAAAAGGTGTTAA
TATTCCAAATACAAAAATTCCTTTCCCAGCACTTGCTGAACGTGATAATGACGATATTCGCTTTGGTTTGGAACAAGGAA
TCAACTTCATTGCTATTTCATTTGTACGTACTGCAAAGGATGTCAATGAAGTTCGTGCAATCTGTGAAGAAACTGGTAAT
GGACATGTGAAATTGTTTGCTAAAATCGAAAATCAACAAGGTATCGAAAATTTGGATGAAATCATTGAAGCTGCTGACGG
TATCATGATTGCTCGTGGTGACATGGGTATCGAAGTACCATTTGAAATGGTTCCAGTTTACCAAAAAATGATTATCACAA
AAGTCAATGCTGCTGGTAAAATTGCTATTACAGCAACAAATATGCTTGAAACAATGACTGAAAAACCACGTGCTACTCGT
TCAGAAGTATCAGATGTGTTCAATGCTGTTATTGATGGAACAGATGCGACAATGCTTTCAGGTGAATCTGCAAATGGTAA
ATATCCACTTGAATCTGTAACAACAATGGCGACAATTGATAAAAATGCTCAAACTCTCTTGAATGAATATGGACGTTTGT
CATCAGTTGACTATGCTCGTAGCTCTAAGACAGAGGTTGTTGCTTCAGCGGTTAAAGATGCTACAAACTCAATGGACATC
AAATTGGTTGTGACAATTACTGAAACAGGTAACACTGCACGTTTGATTTCTAAGTATCGTCCTGATACTGATATTTTAGC
AGTAACATTTGATGAATTGACTCAACGTTCATTGATGTTGAATTGGGGTGTCATTCCAGTTGTAACTGAAAAACCTGCAT
CAACTGATGATATGTTTGAAGTTGCTGAAAAAGTTGCTCTTGCAAGTGGTCTTGTGGAATCTGGCGACAATATTGTGATT
GTGGCTGGTGTACCAGTTGGAACTGGTGGAACAAACACTATGCGTATTCGTACAGTACGTTAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWSEKLDVESSAQNIAKLIEAGANTFRFNFSHGDHAEQGDRMATVHRAEEIAG
QKVGYLLDTKGPEIRTELFEGDAKEYSYKTGEKIRVATKQGIKSTREIIALNVAGALDIYDDVEVGKQVLVDDGKLGLRV
IAKDPATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGN
GHVKLFAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKIAITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQTLLNEYGRLSSVDYARSSKTEVVASAVKDATNSMDI
KLVVTITETGNTARLISKYRPDTDILAVTFDELTQRSLMLNWGVIPVVTEKPASTDDMFEVAEKVALASGLVESGDNIVI
VAGVPVGTGGTNTMRIRTVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 9e-83 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-83 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-82 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 9e-83 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_008496699.1 pyruvate kinase VFG0479 Protein 4e-83 44