Gene Information

Name : guaA (N175_11630)
Accession : YP_008488730.1
Strain :
Genome accession: NC_022223
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 2473289 - 2474842 bp
Length : 1554 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGACTAAAGATATCCATGACCAACGTATTCTGATCTTAGATTTCGGCTCTCAGTACACACAACTGGTTGCCCGCCGTGT
TCGCGAAATCGGTGTTTATTGTGAGCTGTGGAGCTGGGATGTTGAAGAAGCAGACATCCGTGAATTCAACCCAGATGGTA
TTATTCTTTCTGGTGGTCCTGAAAGCGTGACTGAAGCCAACTCTCCGCGTGCGCCACAATATGTGTTTGATTCTGGCGTA
CCTGTGTTTGGTGTTTGCTATGGCATGCAAACCATGGCTGAACAGTTGGGTGGAAAAGTGGCCAGTTCTGAGGAGCGTGA
ATTTGGTTATGCAGCTGTACAGCTGATGGGTGAATCGGTCCTGTTTAGCGACCTTGAGCTGACGCAAGACGTTTGGATGA
GCCACGGTGATAAAGTGGTGCAAATTCCGGCTGATTTTGTCAAAACAGCGCAAACGGAAACTTGTCCTTATGCGGCAATG
GCGAATGAAGAGAAAAAATATTATGGCGTGCAGTTTCACCCAGAAGTGACGCACACCAAAAACGGTCTAAAAATGCTTGA
GAATTTCGTTCTCAACGTTTGTGGTTGTGAGCGTCTATGGACGGCTGAGTCTATCATCGAAGATGCGGTTGCTCGTATTA
AAGAGCAAGTCGGCGACGATGAGGTGATCCTTGGCCTATCGGGTGGTGTAGATTCGTCAGTTGTGGCGATGCTGGCTCAC
CGAGCGATTGGCGATAAATTAACCTGCGTATTCGTTGATAACGGCCTATTGCGTCTGAATGAAGCTCAGCAAGTAATGGA
TATGTTTGGCAACAAATTTGGCTTAAACATCATTCATGTCAATGCAGAAGATCGTTTCCTCAACGCACTGCAAGGTGAGT
CTGATCCGGAAGCGAAACGCAAAATCATCGGCCATGTGTTTGTTGATATCTTCGATGAAGAATCAAAGAAATTGAAAAAT
GCGAAATGGCTTGCGCAAGGCACGATTTACCCAGATGTGATTGAATCGGCCGCCTCTAAAACAGGTAAAGCACACGTGAT
TAAATCTCACCATAACGTTGGCGGTTTGCCTGATGATATGGAAATGGGATTGGTTGAACCACTGCGTGAGCTTTTCAAAG
ATGAAGTACGCAAGATTGGCCTAGAGCTTGGTCTGCCTTACAACATGCTTTACCGCCATCCGTTCCCTGGTCCAGGCCTT
GGCGTACGCGTGTTGGGCGAAGTGAAGAAAGAGTACTGTGATTTGCTGCGCCGAGCCGATGCTATTTTCATTGAAGAGCT
GCATGCCGCTGATCTGTATAACAAAGTGTCACAAGCTTTCACGGTTTTCTTACCTGTTCGTTCGGTAGGCGTTATGGGTG
ATGGACGTAAATACGATTGGGTTGTATCGCTACGTGCTGTGGAAACCATTGACTTTATGACAGCACATTGGGCGCACCTG
CCTTATGAGTTCTTGGGTAAGGTTTCTAACCGTATCATCAATGAAGTGAATGGTATTTCTCGTGTGGTTTACGATATTTC
AGGTAAGCCACCAGCCACCATTGAGTGGGAATAA

Protein sequence :
MTKDIHDQRILILDFGSQYTQLVARRVREIGVYCELWSWDVEEADIREFNPDGIILSGGPESVTEANSPRAPQYVFDSGV
PVFGVCYGMQTMAEQLGGKVASSEEREFGYAAVQLMGESVLFSDLELTQDVWMSHGDKVVQIPADFVKTAQTETCPYAAM
ANEEKKYYGVQFHPEVTHTKNGLKMLENFVLNVCGCERLWTAESIIEDAVARIKEQVGDDEVILGLSGGVDSSVVAMLAH
RAIGDKLTCVFVDNGLLRLNEAQQVMDMFGNKFGLNIIHVNAEDRFLNALQGESDPEAKRKIIGHVFVDIFDEESKKLKN
AKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDDMEMGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGL
GVRVLGEVKKEYCDLLRRADAIFIEELHAADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHL
PYEFLGKVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-132 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-132 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-132 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-114 49