Gene Information

Name : guaA (CARG_08010)
Accession : YP_008479351.1
Strain : Corynebacterium argentoratense DSM 44202
Genome accession: NC_022198
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1671820 - 1673397 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
GTGACTGATAATGCGACCGTAAACCACCGCCCAGTGCTGGTTGTCGACTTCGGAGCCCAGTACGCGCAGCTCATCGCACG
CCGCGTACGCGAGGCCAACATGTACTCCGAGGTCGTCCCGCACACCGCAACAGCCGAAGACATTCGCGCTAAAGATCCAG
CAGCGTTGATTCTCTCAGGTGGACCCTCCTCTGTGTACGAAGACGGCGCACCCAAACTCGATCCCGAAATCCTTGAACTT
GGGGTTCCCGTATTCGGTATCTGCTACGGCTTCCAAGCGATGACCCACGCCCTCGGCGGCGTTGTCGCCAACACCGGCAT
CCGCGAATACGGCCGCACAGACATGATGGTCGACGGCGGAATCCTCCACGAAGGCCTCGACACCACCCACAAAGTCTGGA
TGAGCCACGGCGACGCCGTCCACCAAGCCCCAGAAGGCTTTACCGCAACCGCGCACTCCGAAGGCGCCCCCGTCGCAGCC
TTCGAATGCAAAGAGCGCCGCATGGCAGGCGTGCAATACCACCCAGAAGTACTGCACTCCCCGCATGGCCAACAGGTTCT
CGTACGCTTCCTCACCGACATCGCCGGCCTGGAACAAAACTGGACCGCCGCCAACATCGCCGAAGAACTTATTGACGCCG
TCCGCTCACAGGTAGGCGACACCGGCCGCGCCATCTGCGGACTCTCCGGCGGCGTCGACTCCGCCGTCGCAGCAGCCCTC
GTACAACGAGCCATCGGAGACCGACTCACCTGCGTCTTCGTCGACCACGGCCTCCTCCGAGCAGGCGAACGCGAACAAGT
CGAAAACGACTTCGTCGCAGCAACCGGCGCAAAACTCGTCACCGTCGACGAACGCGCCAACTTCCTCAACAAACTCGCCG
GCGTCACCGAACCAGAAGCCAAACGCAAAGCCATCGGCGCAGAATTCATCCGCTCCTTCGAACGCGCAGTCGCCGGAGTC
CTAGAAGACGCCCCCGAAGGCTCAACCGTCGACTACCTCGTCCAAGGCACCCTCTACCCAGACGTCGTCGAATCCGGCGG
TGGCACCGGCACCGCCAACATCAAAAGCCACCACAACGTCGGCGGCCTCCCCGACGACGTAGAATTCGAACTCGTCGAAC
CCCTACGCCTACTCTTCAAAGACGAAGTCCGCGCAGTCGGCCGTGAACTAGGCCTCCCCGAAGAAATCGTCAACCGCCAA
CCCTTCCCCGGGCCGGGCCTCGGTATCCGCATCATCGGCGAAGTCACTGAAGAACGCCTCGAAACCCTCCGCGCTGCCGA
CCTCATCGCCCGCACGGAACTGACCAACGCAGGCCTCGACGACCAAATATGGCAATGCCCCGTCGTACTCCTCGCAGACG
TTCGCTCCGTCGGCGTCCAAGGCGACGGCCGCACCTACGGACACCCTATCGTCCTACGCCCCGTCTCCTCCGAAGACGCC
ATGACCGCCGACTGGACCCGCATCCCCTACGACGTCCTCGAAAAAATCTCCACCCGCATCACCAACGAAGTCTCCGACGT
CAACCGCGTCGTACTCGACTGCACCTCGAAGCCCCCAGGAACCATCGAATGGGAGTAA

Protein sequence :
MTDNATVNHRPVLVVDFGAQYAQLIARRVREANMYSEVVPHTATAEDIRAKDPAALILSGGPSSVYEDGAPKLDPEILEL
GVPVFGICYGFQAMTHALGGVVANTGIREYGRTDMMVDGGILHEGLDTTHKVWMSHGDAVHQAPEGFTATAHSEGAPVAA
FECKERRMAGVQYHPEVLHSPHGQQVLVRFLTDIAGLEQNWTAANIAEELIDAVRSQVGDTGRAICGLSGGVDSAVAAAL
VQRAIGDRLTCVFVDHGLLRAGEREQVENDFVAATGAKLVTVDERANFLNKLAGVTEPEAKRKAIGAEFIRSFERAVAGV
LEDAPEGSTVDYLVQGTLYPDVVESGGGTGTANIKSHHNVGGLPDDVEFELVEPLRLLFKDEVRAVGRELGLPEEIVNRQ
PFPGPGLGIRIIGEVTEERLETLRAADLIARTELTNAGLDDQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDA
MTADWTRIPYDVLEKISTRITNEVSDVNRVVLDCTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 91
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-131 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-131 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-131 52