Gene Information

Name : ureC (HPSA20_0083)
Accession : YP_008471051.1
Strain : Helicobacter pylori SouthAfrica20
Genome accession: NC_022130
Putative virulence/resistance : Virulence
Product : urease, alpha subunit
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 76675 - 78351 bp
Length : 1677 bp
Strand : -
Note : -

DNA sequence :
ATGTATGGCCCTACTACAGGCGACAAAGTGAGATTGGGCGATACAGAACTGATTGCTGAAGTAGAACATGACTACACCAT
TTATGGCGAAGAACTTAAATTTGGTGGCGGTAAAACTTTAAGGGAAGGCATGAGCCAATCTAACAATCCTAGCAAGGAAG
AATTAGATTTAATCATCACTAACGCTTTGATCATTGACTATACCGGTATTTATAAAGCGGACATTGGCATTAAAGATGGC
AAAATCGCTGGTATCGGTAAAGGCGGTAACAAAGACATGCAAGATGGCGTTAAAAACAATCTTAGCGTAGGTCCTGCTAC
TGAAGCGCTAGCTGGTGAAGGCTTGATCGTAACTGCCGGTGGGATTGACACACACATCCACTTCATTTCACCCCAACAAA
TCCCTACAGCTTTTGCAAGCGGTGTAACAACCATGATTGGTGGCGGAACCGGTCCAGCTGATGGCACTAACGCAACCACT
ATCACTCCAGGTAGAAGAAATTTAAAATGGATGCTCAGAGCGGCTGAAGAATATTCTATGAACTTAGGTTTCTTAGGCAA
AGGTAACGCTTCTAATGACGCAAGCTTAGCCGATCAAATTGAAGCCGGTGCAATTGGCTTTAAAATCCACGAAGACTGGG
GCACCACTCCCTCTGCAATCAACCATGCGTTAGATGTTGCGGACAAATACGATGTGCAAGTCGCTATCCACACAGACACT
TTGAACGAAGCCGGTTGTGTAGAAGACACTATGGCAGCGATTGCTGGGCGCACTATGCACACTTTCCACACTGAAGGCGC
TGGCGGCGGACACGCTCCTGATATTATTAAAGTAGCCGGTGAACACAACATTCTACCCGCTTCAACTAACCCTACTATCC
CTTTCACCGTGAATACAGAAGCCGAACACATGGACATGCTCATGGTGTGTCACCACTTGGATAAAAGCATTAAAGAAGAT
GTCCAGTTCGCTGATTCAAGGATCCGCCCTCAAACCATTGCGGCTGAAGACACTTTGCATGACATGGGGATTTTCTCTAT
CACTAGTTCTGACTCTCAAGCGATGGGCCGTGTGGGTGAAGTTATCACTAGAACTTGGCAAACAGCTGACAAAAACAAAA
AAGAATTTGGCCGCTTGAAAGAAGAAAAAGGCGACAACGACAACTTCAGAATCAAACGCTACTTGTCTAAATACACCATT
AATCCAGCAATCGCTCATGGGATTAGCGAGTATGTCGGTTCTGTGGAAGTGGGCAAAGTGGCTGACTTGGTATTATGGAG
TCCAGCATTCTTTGGTGTGAAACCTAACATGATCATCAAAGGCGGATTCATTGCGTTAAGTCAAATGGGTGATGCGAACG
CTTCTATCCCTACCCCGCAACCGGTTTATTACAGAGAAATGTTTGCCCACCATGGTAAAGCTAAATACGATGCAAATATC
ACTTTTGTGTCTCAAGCGGCTTATGACAAAGGCATTAAAGAAGAGTTAGGGCTTGAAAGACAAGTATTACCGGTTAAAAA
TTGCAGAAATATCACTAAAAAAGATATGCAATTCAACGACACTACCGCTCACATTGAAGTCAATCCTGAAACCTACCATG
TGTTCGTGGATGGCAAAGAAGTAACTTCTAAACCGGCTAATAAAGTAAGCTTAGCGCAACTCTTTAGCATTTTCTAG

Protein sequence :
MYGPTTGDKVRLGDTELIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIIDYTGIYKADIGIKDG
KIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATT
ITPGRRNLKWMLRAAEEYSMNLGFLGKGNASNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADKYDVQVAIHTDT
LNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMVCHHLDKSIKED
VQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTI
NPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAHHGKAKYDANI
TFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKVSLAQLFSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 6e-154 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 6e-154 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-144 60
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-143 60
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-143 60
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-143 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_008471051.1 urease, alpha subunit VFG0270 Protein 0.0 99