Gene Information

Name : HPSA20_1471 (HPSA20_1471)
Accession : YP_008472403.1
Strain : Helicobacter pylori SouthAfrica20
Genome accession: NC_022130
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.14
Position : 1360086 - 1361390 bp
Length : 1305 bp
Strand : -
Note : -

DNA sequence :
ATGCCCCTAAAATCCTTAAAAAACCGCTTGAATCAACATTTTGATCTATCGCCTCGCTACGGGAGCGTGAAAAAAATCAT
GCCCAATATCGTTTATGCGAATGGTTTCAACCCGTCTGTGGGCGATGTGGTGAAGATTGAAAAAAGCGATGGTAGCGAAT
GCGTGGGCATGGTAGTGGTGGTAGAAAAAGAGCAATTTGGTTTCACGCCCTTTAATTTTATAGAGGGATCTAGGGCTGGC
GATAAGGTGCTGTTTTTAAAAGAGGGGCTGAATTTCCCTGTGGGGCATAATCTTTTAGGGCGGGTGCTTAACCCTTTAGG
GCAAGTCATTGACAATAAGGGGGCGTTGGATTATGAACGATTGGCTCCGGTTATCACAACGCCTATAGCCCCCTTAAAAA
GAGGCTTGATTGATGAGGTTTTTAGCGTGGGAGTGAAGAGCATTGATGGGCTTTTGACTTGCGGTAAGGGGCAAAAACTG
GGCATTTTTGCCGGCTCTGGGGTGGGTAAATCCACGCTAATGGGCATGATCACTAGGGGGTGTTTAGCGCCCATTAAAGT
GATCGCTTTAATCGGGGAAAGGGGCAGAGAAATCCCTGAATTTATAGAGAAAAACTTAAAAGGGGATTTAAGCTCTTGCG
TGTTGGTGGTCGCTACAAGCGATGATAGCCCTTTGATGCGAAAATACGGGGCGTTTTGCGCGATGAGCGTGGCGGAGTAT
TTTAAAAATCAAGGGCTAGACGTGTTGTTTATCATGGATTCAGTGACTCGTTTCGCTATGGCTCAAAGAGAAATTGGCTT
GGCTTTAGGCGAACCGCCCACCTCCAAAGGCTACCCTCCATCTGCACTTTCTTTATTGCCTCAATTAATGGAAAGAGCGG
GCAAAGAAGAGGGTAAGGGGAGTATTACCGCTTTTTTTAGCGTGCTTGTAGAGGGCGATGATTTGAGCGATCCGATAGCC
GATCAGGCTAGGAGTATTTTAGACGGGCATATTGTCTTAAGCAGGGAATTAACCGATTATGGGATCTATCCGCCTATTAA
TATTTTAAACTCCGCCTCAAGGGTGGCTAAAGACATTATCAGCGAGTCTCAAAACCTTTATGCAAGAAAATTCCGCCGTT
TGTATGCGTTATTGAAAGAAAATGAAATGCTTATTCGCATCGGATCTTATCAAATGGGGAATGATAAAGAGCTTGATGAA
GCGATCAGTAAAAAGGCTTTAATGGAGCAATTTTTAGCGCAAGATGAAAACGCCTTGCAGCCTTTTGAACAAAGCGTTAA
ACAATTAGAAGAAATCTTAAAATAA

Protein sequence :
MPLKSLKNRLNQHFDLSPRYGSVKKIMPNIVYANGFNPSVGDVVKIEKSDGSECVGMVVVVEKEQFGFTPFNFIEGSRAG
DKVLFLKEGLNFPVGHNLLGRVLNPLGQVIDNKGALDYERLAPVITTPIAPLKRGLIDEVFSVGVKSIDGLLTCGKGQKL
GIFAGSGVGKSTLMGMITRGCLAPIKVIALIGERGREIPEFIEKNLKGDLSSCVLVVATSDDSPLMRKYGAFCAMSVAEY
FKNQGLDVLFIMDSVTRFAMAQREIGLALGEPPTSKGYPPSALSLLPQLMERAGKEEGKGSITAFFSVLVEGDDLSDPIA
DQARSILDGHIVLSRELTDYGIYPPINILNSASRVAKDIISESQNLYARKFRRLYALLKENEMLIRIGSYQMGNDKELDE
AISKKALMEQFLAQDENALQPFEQSVKQLEEILK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-73 50
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-78 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-78 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-78 46
escN AAC38383.1 EscN Virulence LEE Protein 4e-78 46
escN AAC31513.1 L0034 Virulence LEE Protein 3e-78 46
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-77 45
escN AAK26715.1 EscN Virulence LEE Protein 1e-76 45
escN AAL57542.1 EscN Virulence LEE Protein 1e-76 45
escN CAC81862.1 EscN protein Virulence LEE II Protein 4e-77 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 7e-77 45
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-81 44
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-80 44
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-79 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-80 44
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-79 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-80 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-80 44
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-80 43
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-80 43
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 8e-70 43
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 8e-70 43
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-52 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 5e-59 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-52 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 6e-78 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-54 42
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 5e-73 41
escN CAI43874.1 EscN protein Virulence LEE Protein 3e-77 41
escN YP_003223475.1 translocator EscN Virulence LEE Protein 4e-77 41
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-58 41
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 9e-59 41
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-59 41
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-53 41
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-53 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPSA20_1471 YP_008472403.1 flagellum-specific ATP synthase VFG0390 Protein 6e-80 52
HPSA20_1471 YP_008472403.1 flagellum-specific ATP synthase VFG0048 Protein 2e-79 51
HPSA20_1471 YP_008472403.1 flagellum-specific ATP synthase VFG0192 Protein 2e-77 51
HPSA20_1471 YP_008472403.1 flagellum-specific ATP synthase VFG2144 Protein 3e-77 47
HPSA20_1471 YP_008472403.1 flagellum-specific ATP synthase VFG0812 Protein 2e-78 46
HPSA20_1471 YP_008472403.1 flagellum-specific ATP synthase VFG0730 Protein 2e-78 46
HPSA20_1471 YP_008472403.1 flagellum-specific ATP synthase VFG1254 Protein 4e-78 45
HPSA20_1471 YP_008472403.1 flagellum-specific ATP synthase VFG2499 Protein 6e-74 44
HPSA20_1471 YP_008472403.1 flagellum-specific ATP synthase VFG2331 Protein 3e-72 43
HPSA20_1471 YP_008472403.1 flagellum-specific ATP synthase VFG1778 Protein 1e-55 42
HPSA20_1471 YP_008472403.1 flagellum-specific ATP synthase VFG1008 Protein 1e-59 41