Gene Information

Name : fliI (O176_03690)
Accession : YP_008468118.1
Strain : Chlamydia trachomatis D/13-96
Genome accession: NC_022119
Putative virulence/resistance : Virulence
Product : ATP synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 765274 - 766602 bp
Length : 1329 bp
Strand : +
Note : involved in type III protein export during flagellum assembly; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGGAAGAGATAACGACCGAGTTTAATACGCTCATGACGGAATTGCCGGACGTGCAATTAACCGCAGTTGTGGGACGTAT
TATCGAAGTTGTCGGGATGTTAATCAAGGCTGTTGTTCCGGATGTTCGTGTCGGTGAAGTGTGCTTGGTGAAACGTCACG
GGATGGAGCCTCTAGTTACAGAGGTAGTCGGTTTTACGCAGAATTTTGTCTTCCTTTCTCCTTTAGGGGAGTTGACAGGA
GTGAGTCCTTCTTCGGAAGTGATGGCTACTGGATTGCCATTGCATATCCGAGCAGGAGAAGGGTTATTGGGTCGTGTATT
AAATGGTTTGGGAAATCCTATTGATACAGAGACAAAGGGACCTTTAGAGAATGTCGATGCCATTTATCCAATTTTTAAAG
CTCCACCGGATCCGTTGCATCGAGCTAAATTGCGTACGATCTTGTCTACAGGCGTGCGCTGTATTGATGGGATGCTCACT
GTAGCTGAAGGGCAGAGAATCGGAATTTTTGCAGGAGCCGGGGTTGGTAAGTCCTCTTTATTGGGCATGATTGCTCGTAA
TGCTGAAGAGGCAGACATTAACGTAATTGCTTTGATTGGAGAGCGGGGACGAGAGGTTCGCGAGTTCATAGAAAATGACC
TTGGTGAAGAGGGAATGAAACGTTCCGTTATTGTGGTCTCTACTTCTGATCAGTCGTCTCAGCTGCGACTCAATGCTGCC
TACGTAGGAACTGCGATAGCAGAATATTTCCGAGATCAAGGTAAAACGGTTGTATTGATGATGGACTCAGTTACACGTTT
TGCGCGAGCTTTACGTGAAGTGGGGTTAGCGGCTGGAGAGCCTCCTGCTCGTGCTGGGTACACGCCTTCTGTATTTTCCA
CTTTGCCTAAACTGTTAGAAAGAGCAGGAGCCTCTGATAAAGGAACGATTACAGCATTTTATACTGTGTTAGTGGCCGGG
GATGATATGAACGAGCCGGTAGCGGACGAGGTGAAATCCATTTTAGACGGGCATATTGTTCTTTCTAATGCATTAGCGCA
AGCATATCATTATCCAGCGATTGATGTGTTGGCTTCTATTAGCCGATTGCTGACAGCTATTGTTCCTGAGGAACAACGTC
GAATTATTGGGCGTGCTAGAGAGGTTTTAGCTAAATATAAAGCTAATGAGATGTTGATTCGTATTGGGGAGTATCGTCGA
GGATCGGATCGTGAAGTCGATTTCGCAATCGATCATATCGATAAATTAAATCGATTCCTTAAACAAGACATTCATGAAAA
AACAAATTATGAGGAAGCTGCTCAACAGTTGCGAGCAATATTCCGGTAA

Protein sequence :
MEEITTEFNTLMTELPDVQLTAVVGRIIEVVGMLIKAVVPDVRVGEVCLVKRHGMEPLVTEVVGFTQNFVFLSPLGELTG
VSPSSEVMATGLPLHIRAGEGLLGRVLNGLGNPIDTETKGPLENVDAIYPIFKAPPDPLHRAKLRTILSTGVRCIDGMLT
VAEGQRIGIFAGAGVGKSSLLGMIARNAEEADINVIALIGERGREVREFIENDLGEEGMKRSVIVVSTSDQSSQLRLNAA
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPKLLERAGASDKGTITAFYTVLVAG
DDMNEPVADEVKSILDGHIVLSNALAQAYHYPAIDVLASISRLLTAIVPEEQRRIIGRAREVLAKYKANEMLIRIGEYRR
GSDREVDFAIDHIDKLNRFLKQDIHEKTNYEEAAQQLRAIFR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-104 55
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-95 52
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-95 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-95 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-95 52
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-96 52
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-95 52
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-96 52
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-96 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 7e-97 52
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-80 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-80 50
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 8e-80 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-80 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-81 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-79 49
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-79 48
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-79 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 9e-76 47
escN AAC31513.1 L0034 Virulence LEE Protein 2e-82 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-82 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-82 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-82 47
escN AAC38383.1 EscN Virulence LEE Protein 3e-82 47
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-79 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-77 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-78 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-78 47
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 9e-84 47
escN AAK26715.1 EscN Virulence LEE Protein 2e-81 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-81 46
escN AAL57542.1 EscN Virulence LEE Protein 2e-81 46
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-81 46
escN CAC81862.1 EscN protein Virulence LEE II Protein 7e-82 46
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-81 46
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-81 46
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-68 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-72 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-85 46
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 5e-79 46
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-78 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 5e-79 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 4e-72 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 4e-72 45
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 6e-67 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 7e-67 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-63 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-63 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-63 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-63 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_008468118.1 ATP synthase VFG2144 Protein 0.0 99
fliI YP_008468118.1 ATP synthase VFG0192 Protein 7e-110 57
fliI YP_008468118.1 ATP synthase VFG0048 Protein 3e-107 55
fliI YP_008468118.1 ATP synthase VFG0390 Protein 3e-104 55
fliI YP_008468118.1 ATP synthase VFG0515 Protein 2e-80 50
fliI YP_008468118.1 ATP synthase VFG0812 Protein 9e-83 47
fliI YP_008468118.1 ATP synthase VFG0730 Protein 2e-82 47
fliI YP_008468118.1 ATP synthase VFG1008 Protein 2e-63 45
fliI YP_008468118.1 ATP synthase VFG1254 Protein 3e-80 45
fliI YP_008468118.1 ATP synthase VFG2331 Protein 3e-77 44
fliI YP_008468118.1 ATP synthase VFG2459 Protein 4e-69 44
fliI YP_008468118.1 ATP synthase VFG1778 Protein 2e-69 44
fliI YP_008468118.1 ATP synthase VFG0555 Protein 4e-64 43
fliI YP_008468118.1 ATP synthase VFG2499 Protein 2e-76 43