Gene Information

Name : metB (B737_7983)
Accession : YP_008464312.1
Strain : Amycolatopsis mediterranei RB
Genome accession: NC_022116
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 8921772 - 8922929 bp
Length : 1158 bp
Strand : -
Note : -

DNA sequence :
ATGGTGGACGACTACTCCGTACTCGGCTTCGAGACCCGCGCGATCCACGCCGGTCAGAAGCCCGATCCCCGCACCGGCGC
GGTGACCGTGCCGATCTACCAGACCTCGACCTACGCGCAGGACGGCGTGGGCGGTACCCGCGAGGGCGACTACGAGTACT
CGCGCACCGCGAACCCGACCCGTTCGGCGCTGGAGGAGGCGCTGGCCTCGCTGGAAGGCGGCCGGCACGCGCTGGCCTTC
GCGTCCGGCATGGCCGCCTCCGACGTGGTGCTGCGCAGTACCCTCCGCCCCGGTGACCACCTCGTGCTCGGCAACGACGC
CTACGGCGGCACGTTCCGCCTGATCGACAAGGTGCTCAGCCTCTGGGGCGTCGAGCACACCGTCGCCGACCTCGCGGACC
TCGACGAGGTGCGCGCCGCGATCCGGCCCGAGACCAAGCTGATCTGGTGCGAGTCGCCGACCAACCCGATGCTGGGCATC
GCGGACATCGCCGCGCTGGCCGGGGTCGCGCACGACGCCGGTGCCCGCCTGGTGGTCGACAACACCTTCGCGACGCCGTA
CCTGCAGAACCCGCTGGCGCTGGGCGCGGACATCGTCCTGCACTCCACGACCAAGTACCTCGGCGGCCACGCCGACGTCG
TCGGCGGCGCGATCATCACGAACGAGGACGAACTGCGCGAGCAGTTCTTCTTCCTGCGCAACACCGCGGGCGCGGTGCCG
GGGCCGTTCGACGCGTGGCTGACGCTGCGGGGCGTCAAGACCCTCGCCCTGCGCATGGAGCGGCACAGCGACAACGCCGA
GAAGATCGTCCAGGCGCTGATCAAGCACCCGAAGGTGACGAAGGTCTACTACCCGGGCCTGCCGGAGCACCCCGGCCACG
AGACCGCGGCCAAGCAGATGCGCCGCTTCGGCGGGATGGTCTCCTTCCGCCACGTGGACGGCGAACAGGCCGCGCTGGAG
GTGGCTTCGCGCACGAAGCTGTTCATCCTCGCCGAGTCGCTCGGCGGCGTCGAGTCGCTGATCGAGCACCCGGGCAAGAT
GACCCACGCGAGCACGGCGGGTTCGACCCTCCAGGTCCCGGCCGACCTGCTGCGCCTCTCGGTCGGCATCGAAGACGGCC
GCGACCTGGTCGCGGACCTGCTGGCCGCGCTGGGCTGA

Protein sequence :
MVDDYSVLGFETRAIHAGQKPDPRTGAVTVPIYQTSTYAQDGVGGTREGDYEYSRTANPTRSALEEALASLEGGRHALAF
ASGMAASDVVLRSTLRPGDHLVLGNDAYGGTFRLIDKVLSLWGVEHTVADLADLDEVRAAIRPETKLIWCESPTNPMLGI
ADIAALAGVAHDAGARLVVDNTFATPYLQNPLALGADIVLHSTTKYLGGHADVVGGAIITNEDELREQFFFLRNTAGAVP
GPFDAWLTLRGVKTLALRMERHSDNAEKIVQALIKHPKVTKVYYPGLPEHPGHETAAKQMRRFGGMVSFRHVDGEQAALE
VASRTKLFILAESLGGVESLIEHPGKMTHASTAGSTLQVPADLLRLSVGIEDGRDLVADLLAALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-72 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-73 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-59 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_008464312.1 cystathionine gamma-synthase BAC0207 Protein 1e-60 45