Gene Information

Name : O5Y_19965 (O5Y_19965)
Accession : YP_008454541.1
Strain : Rhodococcus erythropolis CCM2595
Genome accession: NC_022115
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 4409133 - 4410305 bp
Length : 1173 bp
Strand : -
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGAGTGAGCAACGCAGCAAGGCCGACAACATCAGCTGGCAGGGTTTCTCCACGAAAGCGGTGCATGCGGGTTACGAACC
CGATCCGCTGACCGGCGCGGTCAACGTGCCGATCTACGCAAGTTCCACCTTCGCCCAAGACGGCGTCGGTGGAATGCGCA
GTGGCTTCGAGTACGCGCGAACGGGCAACCCCACCCGTCGCCCGCTCGAGGCGAACCTTGCCGCGCTCGAATCCGGAACC
TACGGCCGAGCGTTCAGTTCGGGAATGGCGGCCACCGACTGCCTGCTCCGTTCGGTACTTCGACCGGGCGATCACCTGGT
CATCCCCGACGACGCGTACGGCGGAACCTTCCGTCTCATCGACAAGGTGTTCACGCAGTGGGGGATCGAGTACACCCCGG
CTCCGGTGTCCGACGTCGATGCGGTGCGCGCGGCGATGAAGTCCAACACCAAGCTGGTCTGGGTCGAGACGCCCACGAAC
CCGCTGCTCAATATCGGTGACATCGAGCTCCTTGCCGAGGTCGCCCACGAGGGCAACGCAAAGATCGTGGTGGACAACAC
CTTCGCGTCGCCGTACCTGCAGCAGCCGCTGCAGCTCGGTGCCGACATCGCGCTGCACTCCACGACCAAGTACATCGGCG
GACACTCCGACGTGGTCGGTGGCGCTCTCGTCTGCAACGACGAAGAACTGGATACCGCGTTTGCGTTCCTGCAGAACGGA
TCCGGTGGCGTTCCCGGCCCGTTCGACGCGTTCCTGACGTTGCGCGGAATCAAGACACTGGCGCTGCGCATGGAGCGTCA
CAGTGACAACGCGGAGAAGGTCGTCGAATTGCTCGACGGCCACCCCGCGGTTGCCAGCGTCATCTACCCGGGCCTGGCTT
CGCATCCGTCACACAAGGTCGCGGCCAAGCAGATGCGACGCTTCGGCGGCATGATCTCCGTCCGCCTCAAGGGCGGCAAG
GCGGCAGCTCTCGACCTGTGCTCGCGCACCGAGATCTTCACGCTGGCAGAATCTCTCGGCGGCGTCGAATCTCTCATCGA
GTTCCCCGGCGCGATGACCCACGCCTCGACGGCCGGTTCCGCTCTCGAGGTTCCCGACGATCTGGTTCGCCTGTCGGTCG
GCATCGAAGACGCCTCCGATCTGGTCGGCGACATCGAGCAAGCGCTGTCCTGA

Protein sequence :
MSEQRSKADNISWQGFSTKAVHAGYEPDPLTGAVNVPIYASSTFAQDGVGGMRSGFEYARTGNPTRRPLEANLAALESGT
YGRAFSSGMAATDCLLRSVLRPGDHLVIPDDAYGGTFRLIDKVFTQWGIEYTPAPVSDVDAVRAAMKSNTKLVWVETPTN
PLLNIGDIELLAEVAHEGNAKIVVDNTFASPYLQQPLQLGADIALHSTTKYIGGHSDVVGGALVCNDEELDTAFAFLQNG
SGGVPGPFDAFLTLRGIKTLALRMERHSDNAEKVVELLDGHPAVASVIYPGLASHPSHKVAAKQMRRFGGMISVRLKGGK
AAALDLCSRTEIFTLAESLGGVESLIEFPGAMTHASTAGSALEVPDDLVRLSVGIEDASDLVGDIEQALS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-79 47
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-77 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-57 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
O5Y_19965 YP_008454541.1 cystathionine gamma-synthase BAC0207 Protein 1e-64 41