Gene Information

Name : O5Y_12380 (O5Y_12380)
Accession : YP_008453059.1
Strain : Rhodococcus erythropolis CCM2595
Genome accession: NC_022115
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2653724 - 2655388 bp
Length : 1665 bp
Strand : +
Note : COG1021 Peptide arylation enzymes

DNA sequence : 
ATGACCTCGAGGATCGCTCGCGAGCCCTTGGCACCCGTCGCACAGTATCCACCCGATTTGGTGACGCATTATCGGGAACG
AGGCTATTGGACTGACGAGACGCTGGCCGGATTCGTCACGGCCGCGGCCGCACGGCATCCCGACAACGAAGCGGTGGTCG
GCAGCGATGCCTCTGGCACACAGACATTGCTGACGTATTCCGACCTCGATCGTCGCAGCTCGGCCGTGGCCGGAGGCCTG
TCCGGCTTGGGTGTTCGCGCCGGTGACCGGGTGCTCCTGCAGCTACCGAACATCGTGGAATACGTCGAAGCATTGTTCGG
TGTGTTGAAGCTCGGCGCCCTGCCGGTATTCGGGTTGCCGGCGCATCGCCGAACCGAAATCGGATACTTCTGCCAGTTCG
CTGATGTCGCTGCCTATATCGTCGCTGACCGTCATGGCGGGTTCGACTACCGCGCGCTGGCGCGTGAGGTGAACGAAGGC
CTCGAGACTCCGCCTGTTGTGATCGTGGCCGGTGACCCCGAAGAGTTTGTCGGTTTCGATTCGCTGCGCGGATACGAGGT
TCCCGTTCTTGCCGACGTCGATCCGTTGTCGGTCGCCTTTCTTCAGCTTTCCGGTGGCACGACCGGTGTTCCGAAGCTGA
TTCCGCGAACGCACGCCGACTACCTCTACTCGGTGCGAGCGTCCAACCCGATCTGCGGCGTCGACGACTCGACGCGCATG
TTGGTGGTTCTTCCTGCAGCGCATAATTTTCCGATGAGTTCGCCGGGCATCCTGGGTGTTCTCCACGCGGGCGGCTCCGT
GGTTCTGGCGCCGGACACCATGCCCTCCACAGCTTTCGGTCTGATCGAATCAGAGCGAGTCACGCACGCTTCCTTGGTCC
CACCGATCGCGTTGGCCTGGATGGCCGCCCCCAGTAAGGCAGATCACGATCTGTCGAGCTTGCGGGTTCTCGGCGTCGGC
GGAGCGAAGTTCAGCGCCGAAGCCGCTGCACGCGTACCCACGGAGTTGGGCTGCACCCTCCAGCAGGTGTTCGGGATGGC
CGAGGGGCTGGTCAACTACACCCGCCTCGACGACACGCAAGAATTGATCGTCAGCACTCAGGGCCGGCCCATTTCACCCG
ACGACGAGGTTCGTGTGGTCGACGACGAAGGCGCGCTCGTCGCGCCCGGAACCACGGGGCACTTACTGACTCGGGGTCCG
TATACGATCCGTGGCTATTACCGGGCGGATGCGCACAATGCCGAGGTCTTCGACGCCGAAGGTTTCTATCGCACCGGCGA
TCTGGTCAGCGTCACCGATTCAGGACATCTGATAGTCGAGGGGCGCGCAAAAGACCAGATCAACCGCGGCGGTGAGAAGG
TTGCGGCCGAGGAGATCGAGAACCACCTGCTCTCGCATCCGGCTGTCCACGATGCGGCCGTCGTCGCTGTTCCCGACGAG
TACCTGGGCGAACGAACCTGTGCTGTCCTGGTGATTTCCGGAAATGTGCCGACCGTCGGCGAGATCAAACGATACATACG
AGGCCGAGGCGTTGCGGCGTACAAGGTTCCGGATCGAGTGGAGTTCGTGACCGAGTTCCCCGTCACCGGCGTCGGAAAGA
CCAGCAAGGCGGCCTTGCGCCGTGTTCTCAGCGAATCGATTGCCGCACAGACTCTGTCGAGTTGA

Protein sequence : 
MTSRIAREPLAPVAQYPPDLVTHYRERGYWTDETLAGFVTAAAARHPDNEAVVGSDASGTQTLLTYSDLDRRSSAVAGGL
SGLGVRAGDRVLLQLPNIVEYVEALFGVLKLGALPVFGLPAHRRTEIGYFCQFADVAAYIVADRHGGFDYRALAREVNEG
LETPPVVIVAGDPEEFVGFDSLRGYEVPVLADVDPLSVAFLQLSGGTTGVPKLIPRTHADYLYSVRASNPICGVDDSTRM
LVVLPAAHNFPMSSPGILGVLHAGGSVVLAPDTMPSTAFGLIESERVTHASLVPPIALAWMAAPSKADHDLSSLRVLGVG
GAKFSAEAAARVPTELGCTLQQVFGMAEGLVNYTRLDDTQELIVSTQGRPISPDDEVRVVDDEGALVAPGTTGHLLTRGP
YTIRGYYRADAHNAEVFDAEGFYRTGDLVSVTDSGHLIVEGRAKDQINRGGEKVAAEEIENHLLSHPAVHDAAVVAVPDE
YLGERTCAVLVISGNVPTVGEIKRYIRGRGVAAYKVPDRVEFVTEFPVTGVGKTSKAALRRVLSESIAAQTLSS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-97 49
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 7e-97 49
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-97 49
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-97 49
ybtE CAA21394.1 - Virulence HPI Protein 7e-97 49
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 6e-97 49
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 8e-97 48
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 2e-95 48
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-95 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
O5Y_12380 YP_008453059.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 9e-116 50
O5Y_12380 YP_008453059.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 6e-101 46
O5Y_12380 YP_008453059.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 5e-105 46