Gene Information

Name : O5Y_08730 (O5Y_08730)
Accession : YP_008452334.1
Strain : Rhodococcus erythropolis CCM2595
Genome accession: NC_022115
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1856147 - 1857646 bp
Length : 1500 bp
Strand : +
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGACGGCAGTAGCCGAACACACCATCAGTTCCGCGGTACAGGGTTTCCTGAACGGACCGAAGAAGCTCTACATCGGCGG
CGAATTCGTCGACGCCGCTTCGGGTCAGACCTTCGCGACGTACAACCCGGCTGACGGACAGAAGCTCGCAGACGTGGCAC
ACGGCCAGGCCGAAGACATCGACCGCGCGGTACGCGCCGCCCGAACGGCTTTCGAGGACGGCCCCTGGTCTCGGATGAAG
GCAAACGAGCGCGAGCGGATGATCTGGCGCGTCGGCGACATTCTCAGTGCTCGTGCCGAGGAATTCGGTCAGCTCGAAGC
TCTCGACAACGGCAAGTCCGTTGCCATCGCCACCGCCGTCGACGTGGCTTGGGCCGCAGACGTTTTCCGCTACTACGCGG
GTTGGGCCACCAAGATCGAAGGCAGCACCGTCAACGTGTCGATGCCCTTCTCTCCGGGCGGCGAGTTCCACGCCTACACC
CTGCGTGAGGCAATCGGCGTCTGTGGACTGATCGTGCCGTGGAACTTCCCGCTGCTGATGTCGTCGTGGAAGCTCGCCCC
CGCGCTCGCCGCCGGCAACACGGTGATCCTCAAGCCCGCTGAGCAGACCCCGCTCACCGCACTGCTTCTCGCGGAGGTCT
TCGAAGAAGCAGGCTTCCCGCCCGGCGTCGTCAACATCGTTCCCGGCTTCGGCGATGCAGGTGCTGCACTGTCCGGCCAC
GACGACGTGGACAAGGTCGCGTTCACCGGTTCCACCGAGGTGGGTAAGAAGATCGTCGACGCCGCCAAGGGCAACCTGAA
GAAGGTTACGCTCGAGCTCGGTGGCAAGAGCCCCAACATCGTATTCGCCGACGCGGATTTCGATTCCGCGGTGGAGGGTT
CACTCAACGCCTGGCTGTTCAACCACGGTCAGTGCTGCGTTGCGGGTACCCGTCTGTACGTCGAGGACACCATCTTCGAG
AAGTTCACCGAGGCCGTCGCGCACGCAGCGAGCCAGGTCAAGATCGGACCCGGCCTCGATCCCACCACCCAGCTCGGACC
GCTGGTCTCGCAGGAGCAGTTCGACAAGGTCACCGGTTACCTCCGTGAGGGAATCGCCGACGGCGCACGTGCACTCACCG
GCGGTAACCGCTGGGGCGATCAGGGCTACTTCGTCGAGCCGACTGTCTTCGTCGACGTCAAGCCCGAATTCTCCATCGTT
CAGGAGGAGATCTTCGGACCCGTCGTGGCAGCGCTGCCGTTCAACGCGGACGACGGACCCATCACTGCCGCAAACGATTC
CATCTACGGACTTGCCGCCGGCATCTGGACCCGTGACATTTCCAAGGCCCACCGCACGGCCAAGCGTCTCAAGGCTGGCT
CGGTGTGGATCAACCAGTACAACGGCTTCGACACCGCAATGCCTTTCGGCGGATACAAGCAGTCCGGTTGGGGCCGCGAG
CTCGGCGCTTCGGCTATCGATCTCTACACCCAGACCAAGGCCGTCAACATCGCCCTCTGA

Protein sequence :
MTAVAEHTISSAVQGFLNGPKKLYIGGEFVDAASGQTFATYNPADGQKLADVAHGQAEDIDRAVRAARTAFEDGPWSRMK
ANERERMIWRVGDILSARAEEFGQLEALDNGKSVAIATAVDVAWAADVFRYYAGWATKIEGSTVNVSMPFSPGGEFHAYT
LREAIGVCGLIVPWNFPLLMSSWKLAPALAAGNTVILKPAEQTPLTALLLAEVFEEAGFPPGVVNIVPGFGDAGAALSGH
DDVDKVAFTGSTEVGKKIVDAAKGNLKKVTLELGGKSPNIVFADADFDSAVEGSLNAWLFNHGQCCVAGTRLYVEDTIFE
KFTEAVAHAASQVKIGPGLDPTTQLGPLVSQEQFDKVTGYLREGIADGARALTGGNRWGDQGYFVEPTVFVDVKPEFSIV
QEEIFGPVVAALPFNADDGPITAANDSIYGLAAGIWTRDISKAHRTAKRLKAGSVWINQYNGFDTAMPFGGYKQSGWGRE
LGASAIDLYTQTKAVNIAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-77 45
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-84 43
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-84 43
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-84 43
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-84 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-83 42
hpaE AAO17179.1 HpaE Not tested tcd island Protein 6e-78 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
O5Y_08730 YP_008452334.1 aldehyde dehydrogenase VFG0082 Protein 2e-83 42