Gene Information

Name : megL (TPE_1938)
Accession : YP_008435548.1
Strain : Treponema pedis T A4
Genome accession: NC_022097
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.11
Position : 1986496 - 1987707 bp
Length : 1212 bp
Strand : +
Note : -

DNA sequence :
ATGGAGGAAAACATGAATAAAGACGAATTGAAAAATATGGGTTTTGCTTCAAAGCAAATCCATGCCGGTTACGAAAAAAA
TAAATACGGGGCGTTAGCTACCCCTATTTATCAAACGTCAACCTTTATTTTCGATTCTGCGGAACAGGGCGGAAAAAGAT
TTGCCCTTGAAGAAGAAGGGTATATTTATACCCGCCTGGGGAATCCTACCGCTACGGTTGTTGAGGAAAAACTTGCCTGC
CTTGAAAACGGAGAAGCTTGTATATCCGCAAGCTCAGGTATGGGAGCGATTACGTCCTGCCTTTGGACGCTTGTCAGCGC
GGGCGACCATATAGTAGCAGGTAAAACCCTTTACGGTTGTACTTTTGCATATTTTAGTCACGGACTTTCACGTTTCGGAG
TTGATGTTACCTTTGTGGATACGCGGAATCCCGAAAATGTACGCAAGGCAATGAAAGCGAATACTAAAGTAGTATATCTT
GAAACTCCTGCAAACCCTAATATGTATTTATGCGACATAAAAACAATCAGCGAAATTGCACATACAAATCCGGATTGTAA
GGTAGTTGTGGATAATACATATATGACGCCATATTTACAACGGCCGTTGGATTTGGGAGCCGATGTCGTCGTTCACTCGG
CAACAAAATATCTGAACGGACACGGAGATGTAATTGCGGGCTTTGTTGTAGGTAAAAAAGAATTTATCGACCAAGTACGT
TTTGTAGGTGTAAAAGATATGACAGGTTCCACCTTAGGCCCCTTTGAAGCCTATTTAATCGGCAGAGGTATGAAAACCTT
AGACATACGTATGGAAAAACATTGTGCAAATGCTCAAAAAGTTGCCGAATTTTTAGAAACACACCCTGCCCTTGAATCGA
TTTACTATCCCGGGTTAAAGTCTTTTCCGCAATATGAACTTGCAAAAAAACAAATGATGTTACCGGGAGCAATGATTGCC
TTTACTGTAAAAGGCGGCTGCGAAGCGGGCAGAAACTTGATGAACAGAGTAAAATTCGCTACTCTGGCGGTAAGTTTAGG
GGACGCCGAAACCCTGATTCAACACCCTGCAAGTATGACGCACTCTACATATACTCCGGAAGAAAGAGCCGCATCGGATA
TTGCGGAAGGTTTAGTACGCCTTTCGGTAGGGCTTGAAGATTCCAAAGATATTATAGCGGATTTAAAACAGGCTCTGGAC
AGTTTAAAATAA

Protein sequence :
MEENMNKDELKNMGFASKQIHAGYEKNKYGALATPIYQTSTFIFDSAEQGGKRFALEEEGYIYTRLGNPTATVVEEKLAC
LENGEACISASSGMGAITSCLWTLVSAGDHIVAGKTLYGCTFAYFSHGLSRFGVDVTFVDTRNPENVRKAMKANTKVVYL
ETPANPNMYLCDIKTISEIAHTNPDCKVVVDNTYMTPYLQRPLDLGADVVVHSATKYLNGHGDVIAGFVVGKKEFIDQVR
FVGVKDMTGSTLGPFEAYLIGRGMKTLDIRMEKHCANAQKVAEFLETHPALESIYYPGLKSFPQYELAKKQMMLPGAMIA
FTVKGGCEAGRNLMNRVKFATLAVSLGDAETLIQHPASMTHSTYTPEERAASDIAEGLVRLSVGLEDSKDIIADLKQALD
SLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-69 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-70 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
megL YP_008435548.1 methionine gamma-lyase BAC0207 Protein 6e-108 57