Gene Information

Name : clpA (TPE_0163)
Accession : YP_008433795.1
Strain : Treponema pedis T A4
Genome accession: NC_022097
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 161217 - 163748 bp
Length : 2532 bp
Strand : -
Note : -

DNA sequence :
ATGAAATTGATGATAAGCGATACGGTTCAAACCATTTTTAATGAAGCTACTTTAGAAGCAAAAAAACATAAACATGAGTT
TGTAACGCCGGAACATGTGTTGTGGGCTATGATGTTCCACCCTAAAATATTGGAGCTTTTTACTCTTTCGGGTGCGGATT
TAGGTTATATGCATGACAGCACCATGGATTATCTTAAAAATAAAGTCCCTTATTTTCCTCAAGATAAAAATGATGAGCCC
GTACAAAGTTTGGGGCTGCAAACGGTATTTGACAGAGCCGTGGATTATTGTATAAATTCCGGGAAAAAAATAATAAGTTT
TAACAACCTTGTCGTAGGCCTCTTTGACGAAGATAAAAACCATTGTTCTTTTTTTATGAGACAGGGGGGAATAAACCGCC
TGCGTCTTTTACAGCTTTTAAGCACGGATGAATTCTATGATGACGGAGAAGCCGATGTAAACTATGTTGAATGTGCAAGT
CAAAAAAATGAAGGGCAGCTGTTTGTCGAAGTTGAAACTATAGAGGGCGGTATAGGAATACACGAAAACGACCGCAGTAT
AAGAGCTTTTCAGGATTTTATACAGGGTCAAGTAAAAAATAACGGTAAAAGTAACGGAAAAAATGACGATATGAATTTTT
CAAGACAAAGCGGCGGAAGAAAAAAAACTAAAACGGTTCTTGAAAGGTTTACCGTAAATTTAACGGAAAAAGCAAGAGAG
GGATTGCTTTCTCCTCTTATAGGCAGAACGGAAGAAATAGAAAGAACGATTCAGATTTTATGCAGAAAGCAAAAAAATAA
CGTACTCCATGTAGGAAGTGCGGGAGTCGGTAAAACCGCAATAACGGAAGGTCTTGCTCAAAAAATTGCGGAAGGCAATG
TTCCTTCTTTTTTAAAAGATGCGAATATTTATGCTGTAAGTATGTCCGATTTAATGGCAGGTTCCAAATTTAGGGGAGAT
TTTGAAGACCGCTTAAAACATATAGCGCGTGAAATTGCAGCTGAAAAAAATTCCATTATGTTTATAGATGAAATTCACAC
TGTAATAGATACAAACGGCGGCAGCGGTATTGAAGCCCCGGATTTGTTAAAACCTCTTTTAAGCGGCGGAAAAATACGCT
GTATAGGGGCTACCACTTATGAAGAATATGAGCGTTACTTTTTAAAAGATAAGGCCCTTGCACGCCGCTTTCAAAAGGTC
GATATAGAAGAACCGTCGGAAGACGAAGCTTTAAAAATTCTGCAAGGGTTACGCAGCTCCTATGAGGATTTTCACCGCGT
ACGCTATAGCGATGAGGTTTTGCGCGCTGCGGTTCATCTTTCGGCACTTCATATCCGCGAAAGATTTTTACCGGACAAGG
CAATAGATTTAATAGATGAAGCGGGAGCTCTTTTAAAAATCAGAGCGGATAAAAATAAATTTGAGTACTCTCTGTCTGAA
GAAAGATTTAAAACGGTTCCGCAAACGGAAACCGCCGAAGAGCTTTCACAAAAGACGGAGACGAAAGAAGCTGTAAACCC
CGAAAACGGGTTTACTCAAGTAAGCGTTTCGGATATAGATAAGATTGTAGCAAAAACCGCAAAAATCCCTGAACGGGCGG
TTTCGGTAAACGAAACGGAAAAGCTCAAAAACTTTGAAGAAATTCTTTCCAAAAAGATTTTCGGACAAGCGGAAGCAATT
ACGGGCGTAACAAAGGCGGTAAAAAGGTCAAGAGCGGGCTTTAGGGCCAAAGAAAAACCGGTTGCAAACTTTTTATTTGT
GGGACCTACCGGAGTAGGCAAAACGGAACTTGCAAAAACCCTTGCCGAAGAACTCGGTATTCCGCTTCTCCGTTTTGATA
TGAGCGAATATCAGGAAAAACATACCGTAAGCCGCCTAATAGGTTCGCCGCCCGGCTATGTCGGCTTTGAAGACGGAGGT
CTTTTAACCGAATCCGTCCGTAAACAGCCCAACTCCGTTTTACTTTTAGACGAAATCGAAAAAGCTCACAGGGATATTTA
TAATATTCTTTTACAAATTATGGATTATGCCACTCTTACGGATAACCAGGGCAGAAAAGCGAGTTTTAATAATGTCATTT
TAATTATGACAAGCAATGCGGGTTCATCGGAAATCGGAAAACCGCTTATCGGGTTCGGAGGGGATACCGTTTCGGAATCC
GCAATAGATGAAGCGGTGGAAAAAACTTTTACACCCGAATTCAGAAACAGGCTCGATGCGGTTATAAAATTCGGTCCGCT
TACCATGCCGGTAATGAGCTTAATCGTTAAAAAAGAAGTGGAAAAAATAAAAACTCACCTTGCCGAAAAAGAAATTGAAC
TTGAGCTTTCAAATGAGGTTATTCCGTTGCTCGCGGAAAAAGGTTATTCGCCGGAATTCGGAGCAAGAAATGCCGCTCGT
TTGGTAGAAGATGAATTCGTAACGCCTCTTACCGATATGATTTTGTTCGGTACCGCAAAAAAAGGAGGAGCGGTATCATG
TACGGTTGCAAATAAGAGTAAAAAACCTTATTTGAAGTTAAATGTTAAATAA

Protein sequence :
MKLMISDTVQTIFNEATLEAKKHKHEFVTPEHVLWAMMFHPKILELFTLSGADLGYMHDSTMDYLKNKVPYFPQDKNDEP
VQSLGLQTVFDRAVDYCINSGKKIISFNNLVVGLFDEDKNHCSFFMRQGGINRLRLLQLLSTDEFYDDGEADVNYVECAS
QKNEGQLFVEVETIEGGIGIHENDRSIRAFQDFIQGQVKNNGKSNGKNDDMNFSRQSGGRKKTKTVLERFTVNLTEKARE
GLLSPLIGRTEEIERTIQILCRKQKNNVLHVGSAGVGKTAITEGLAQKIAEGNVPSFLKDANIYAVSMSDLMAGSKFRGD
FEDRLKHIAREIAAEKNSIMFIDEIHTVIDTNGGSGIEAPDLLKPLLSGGKIRCIGATTYEEYERYFLKDKALARRFQKV
DIEEPSEDEALKILQGLRSSYEDFHRVRYSDEVLRAAVHLSALHIRERFLPDKAIDLIDEAGALLKIRADKNKFEYSLSE
ERFKTVPQTETAEELSQKTETKEAVNPENGFTQVSVSDIDKIVAKTAKIPERAVSVNETEKLKNFEEILSKKIFGQAEAI
TGVTKAVKRSRAGFRAKEKPVANFLFVGPTGVGKTELAKTLAEELGIPLLRFDMSEYQEKHTVSRLIGSPPGYVGFEDGG
LLTESVRKQPNSVLLLDEIEKAHRDIYNILLQIMDYATLTDNQGRKASFNNVILIMTSNAGSSEIGKPLIGFGGDTVSES
AIDEAVEKTFTPEFRNRLDAVIKFGPLTMPVMSLIVKKEVEKIKTHLAEKEIELELSNEVIPLLAEKGYSPEFGARNAAR
LVEDEFVTPLTDMILFGTAKKGGAVSCTVANKSKKPYLKLNVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-121 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpA YP_008433795.1 ATP-dependent Clp protease, ATP-binding subunit ClpA VFG0080 Protein 5e-117 43
clpA YP_008433795.1 ATP-dependent Clp protease, ATP-binding subunit ClpA VFG0079 Protein 3e-119 42