Gene Information

Name : clpB (TPE_1073)
Accession : YP_008434705.1
Strain : Treponema pedis T A4
Genome accession: NC_022097
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1166545 - 1169124 bp
Length : 2580 bp
Strand : -
Note : -

DNA sequence :
ATGAATATGGATAAATACACCGTTAAAGCAAGCGAAGCCGTGCAGGAAGCTTCGTCCCTTGCTCAGCGGGACGACCACAG
TCAAATTGAAAGCGAACATCTTTTGTATGTTCTTTTGGAACAGGAAGACGGAATTGTTCCGCCGATTGTAGAAAAGATAG
GCGTTCAGCCTGATTCTATTTTAGATGAACTTGATAAAATCCTCGATAAAAAGCCCCGAGTTACGGGACAGTCGGCACAA
ACTTATATGTCGCCACTTTTGGCAAAAGTGTTTGCCCATGCGGAAGGATATGCCGATAAACTGAAAGACGATTACGTTTC
TACAGAGCATTTTCTTTTAGCTTTAACCGAAGCGCAAGATTCTGCGGGAAATCTTTTACGTTCCCGCGGAATAAATTTTA
AAGCGGTTCTTTCCGCATTAAAAGAAATACGCGGTAATAACCGTGTTACAACCGATAATCCCGAATCGACTTTTCAAAGT
TTGGAAAAATTTTGCCGCGATTTAACACAGCTTGCACGTCAGGAAAAAATAGACCCGGTTATAGGCCGCGATGAAGAAAT
AAGGCGTGTTATGCAAGTGCTTTCGCGCCGAACGAAAAACAATCCGGTTTTAATAGGAGAGCCTGGTGTAGGAAAAACCG
CAATAGTTGAAGGGCTTGCACGGAGAATTGTTTCAGGCGATGTTCCCGACAGCTTAAAGGGAAAGCGCCTTTTATCGCTT
GACTTGGGAGCCTTGGTTGCGGGTGCAAAATTCCGCGGAGAATTTGAAGAGAGGCTTAAGGCTGTAATTTCCGAAGTACA
AAAATCGGAAGGCAAGGTTATTTTATTTATAGATGAGCTTCATACTCTGGTAGGAGCCGGTGCGAGTGAAGGGTCTATGG
ACGCTTCAAATCTTTTAAAGCCCGCCTTAGCACGGGGAGAACTTCGAGCAATCGGTGCTACTACTCTCAATGAATACCGC
AAATATATAGAAAAAGATGCCGCTCTTGAGCGCCGGTTTCAGCAAGTGTATTGCCCGGAACCGACAGTGGAAGATACGAT
TGCAATATTGCGCGGTTTGCAGGAAAAATATGAAGTGCATCACGGCGTAAGAATTCGCGATGAAGCGTTAATTGCAGCAG
CCGTTCTTTCCGACCGCTACATAACAAGCCGCTTTTTGCCGGATAAGGCAATAGACTTGGTTGATGAAGCCGCAAGCCGT
CTTAAAATGGAAATTGAAAGTCAGCCCGTAGAGCTTGACCAGGTCGAACGGAAAATTTTGCAATTAAACATAGAAAAAGT
TTCTATCGGTAAAGAATCCGATGCGGCTTCAAAAGAAAGACTTAAAAAAGTGGAAGAAGAACTCGCAGAGCTAAGCGAAA
AACGGAATGCTATGCAGGCTCAGTGGCAAAATGAAAAATCCCGCATAGACGAATCCCGTGAATATAAAAAAGAGTTGGAG
CAGCTTAGAAATGAAGAAACTCGCTACAGCCGCGAAGGAAATTTAAATAAGGCTGCCGAATTAAAATACGGAAAAATCCC
GGAACTTGAAAAAAAGATTGCGGCGGTTACCGCCGAACTTGAAAAAAAAGCGGGTTCCGCAGGACAGCTTTTGCGCGAAG
AAGTTTGCGAAGAAGATATAGCTAAAATAGTTTCAATGTGGACGGGGATTCCTGTTGCAAAAATGATGGCAAGCGAAATG
CAAAAATACTTGGATTTGGAAAAGGTTTTACAACAGCGAGTTGTCGGACAAGACGAAGCCGTACGGGTTACTGCGGACGC
AATCCGCAGAAACAAGGCGGGTCTTTCCGATATGAACCGTCCTTTGGGAAGTTTTTTGTGCATAGGCCCTACAGGTGTCG
GTAAAACCGAACTTGCCCGTACGCTTGCGGATTTTTTATTTAATGATGAAAAAGCTTTGACAAGAATCGATATGAGCGAA
TATATGGAAAAACATTCCGTAAGCCGCTTAATCGGAGCTCCTCCGGGATATGTCGGTTATGATGAGGGCGGTCAGCTTAC
CGAAGCCGTCCGCCGCCGTCCTTACAGCGTAGTCTTATTCGACGAAATCGAAAAAGCACATCAGGATGTGTTTAATGTAT
TTTTACAGATTTTAGATGACGGAAGACTTACGGACGGACAGGGCAGAATAATAGATTTTAAAAATACGATTATAATTATG
ACGAGCAATATCGGTTCGGAATTTATTCTCGGTGCAAAAGATATGAAGAGTATAAAACCGCAAATTACCGAAATTTTACG
CGCTAACTTTAAACCCGAATTTTTAAACCGTATTGATGAAATTATTACATTTAACCGGCTCGAAAAAGAACATATACGTA
AGATTGTTGAAATCCAGCTCGCTTCCGTTGCGGAGCGTCTTCAAGCCCGCCGCTTGAATTTAAAAGTTTCGGACGCCGCA
AAGGATTTACTTGCCGACATAGGCTTTGACCCGATGTTCGGGGCAAGACCTTTAAAAAGGGCAATTCAAGCAGAACTTGA
AAATAAACTTGCACGTGAAGTGCTTGAAGGTAAATTCCCGGAAGGCTCTACTATCTTTGTCGATAAGGGAGAAGCGGGAT
TAACTTTTAAAAAAGGGTAA

Protein sequence :
MNMDKYTVKASEAVQEASSLAQRDDHSQIESEHLLYVLLEQEDGIVPPIVEKIGVQPDSILDELDKILDKKPRVTGQSAQ
TYMSPLLAKVFAHAEGYADKLKDDYVSTEHFLLALTEAQDSAGNLLRSRGINFKAVLSALKEIRGNNRVTTDNPESTFQS
LEKFCRDLTQLARQEKIDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVSGDVPDSLKGKRLLSL
DLGALVAGAKFRGEFEERLKAVISEVQKSEGKVILFIDELHTLVGAGASEGSMDASNLLKPALARGELRAIGATTLNEYR
KYIEKDAALERRFQQVYCPEPTVEDTIAILRGLQEKYEVHHGVRIRDEALIAAAVLSDRYITSRFLPDKAIDLVDEAASR
LKMEIESQPVELDQVERKILQLNIEKVSIGKESDAASKERLKKVEEELAELSEKRNAMQAQWQNEKSRIDESREYKKELE
QLRNEETRYSREGNLNKAAELKYGKIPELEKKIAAVTAELEKKAGSAGQLLREEVCEEDIAKIVSMWTGIPVAKMMASEM
QKYLDLEKVLQQRVVGQDEAVRVTADAIRRNKAGLSDMNRPLGSFLCIGPTGVGKTELARTLADFLFNDEKALTRIDMSE
YMEKHSVSRLIGAPPGYVGYDEGGQLTEAVRRRPYSVVLFDEIEKAHQDVFNVFLQILDDGRLTDGQGRIIDFKNTIIIM
TSNIGSEFILGAKDMKSIKPQITEILRANFKPEFLNRIDEIITFNRLEKEHIRKIVEIQLASVAERLQARRLNLKVSDAA
KDLLADIGFDPMFGARPLKRAIQAELENKLAREVLEGKFPEGSTIFVDKGEAGLTFKKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 6e-106 44
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-155 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-105 43
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-105 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_008434705.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG2084 Protein 4e-111 44
clpB YP_008434705.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG2076 Protein 7e-120 43