Gene Information

Name : N559_1244 (N559_1244)
Accession : YP_008424288.1
Strain : Klebsiella pneumoniae JM45
Genome accession: NC_022082
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase B (lactaldehyde dehydrogenase)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1240332 - 1241852 bp
Length : 1521 bp
Strand : +
Note : -

DNA sequence :
ATGCGTTATGCACATCCTGGCCAGCCCGGCGCCGTGGTTTCATTTAAATCGGCTTACGGCAACTTTATTGACGGTAGATT
TGTCGAGCCGCTGAGCGGTGAATTCTTTATGAATACTTCGCCGGTCGACGGCTGCAACATTGCGCAGTTTCCCCGCTCGG
ATGCCAGAGACATTGACTTCGCCCTCGACGCTGCCCATCGCGCGGCGCCGGCGTGGGGTAAAACCTCAGTGCAACAGCGC
TCCAGGCTGCTGCTGCAGGTCGCCGATCGTATTGAACAGCATCTGGAATATCTGGCGGTGGCGGAGAGCTGGGACAATGG
GAAACCGATCCGCGAAACCCTGAATGCTGACCTGCCGCTGGCGGTGGATCATTTTCGCTACTTCGCCGGCTGCCTGCGCG
CTCAGGAGGGAAGCACCGCCGAGATTGACGAAACCACGGTGGCCTATCATTTCCATGAACCGCTGGGGGTGGTCGGGCAG
ATTATCCCGTGGAACTTCCCGCTGCTGATGGCCGCGTGGAAGCTGGCCCCGGCCCTGGCGGCGGGGAACTGCGTGGTGCT
CAAGCCGGCGGAACAGACGCCGCTAAGCATTACCCTGCTGCTGGAGCTGATCGGCGATCTGTTCCCGGCCGGGGTGCTTA
ACGTGGTGCAGGGTTTCGGCAAAGAGGCGGGCGAGGCGCTGGCCACCAGCAAGCGTATCGCCAAGCTGGCGTTTACCGGC
TCCACGCCGGTCGGGCGGCATATTCTCGCCTGCGCGGCGGAAAATATTATCCCCTGCACCGTCGAGCTGGGGGGGAAATC
GCCCAACATCTACTTCGCCGACGTGATGGACGGAGAAGAGGAATTTATTGAGAAGGCGGTGGAGGGGCTGGTGCTCGGCT
TCTTCAACCAGGGTGAGGTCTGTACCTGCCCGTCGCGGGCGCTGATCCATGAATCCATCTATGAGCCCTTTATGGCACGG
GTCATGGAGAAGGTGGCGCAGATCCGCCGCGGCGATCCGTTAGATACCGACACCATGATCGGCGCTCAGGCTTCCCGCCA
GCAGTTCGACAAGATCCTCTCCTATATTCAGATTGCCCGGGAAGAGGGTGGGCAAATTCTGACCGGAGGCGAGCGGGCGG
CTATCGCGCCGGCGCTGGATAATGGCTTTTATATTCAGCCCACGCTGATTAAAGGTCGCAACGATATGCGTTCCTTCCAG
GAGGAGATCTTTGGGCCGGTGATCGGGGTGACCACCTTTAAGGACGAAGCGGAAGCGCTGGCTATCGCCAATGAGACCCA
GTTTGGTCTCGGCGCCGGGGTGTGGACGCGGGATACCAACCTCGCCTATCGCATGGGTCGCGGCATTAAAGCCGGTCGCG
TGTGGACCAACTGCTATCATGTCTACCCGGCGCATGCGGCGTTCGGCGGCTATAAACAGTCCGGCGTCGGGCGGGAAACG
CACAAGATGGCGCTGGATGCCTATCAGCAAACCAAAAACCTGCTGGTGAGCTACGGCACCGCGCCGCTGGGCCTGTTCTG
A

Protein sequence :
MRYAHPGQPGAVVSFKSAYGNFIDGRFVEPLSGEFFMNTSPVDGCNIAQFPRSDARDIDFALDAAHRAAPAWGKTSVQQR
SRLLLQVADRIEQHLEYLAVAESWDNGKPIRETLNADLPLAVDHFRYFAGCLRAQEGSTAEIDETTVAYHFHEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLSITLLLELIGDLFPAGVLNVVQGFGKEAGEALATSKRIAKLAFTG
STPVGRHILACAAENIIPCTVELGGKSPNIYFADVMDGEEEFIEKAVEGLVLGFFNQGEVCTCPSRALIHESIYEPFMAR
VMEKVAQIRRGDPLDTDTMIGAQASRQQFDKILSYIQIAREEGGQILTGGERAAIAPALDNGFYIQPTLIKGRNDMRSFQ
EEIFGPVIGVTTFKDEAEALAIANETQFGLGAGVWTRDTNLAYRMGRGIKAGRVWTNCYHVYPAHAAFGGYKQSGVGRET
HKMALDAYQQTKNLLVSYGTAPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-154 66
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 6e-107 65
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 6e-107 65
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-160 64
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-160 64
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-160 64
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-159 64
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 7e-57 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
N559_1244 YP_008424288.1 aldehyde dehydrogenase B (lactaldehyde dehydrogenase) VFG0082 Protein 3e-154 66