Gene Information

Name : dhbE (BASU_2825)
Accession : YP_008422235.1
Strain : Bacillus amyloliquefaciens UCMB5113
Genome accession: NC_022081
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.58
Position : 3022483 - 3024108 bp
Length : 1626 bp
Strand : -
Note : Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; PubMedId:8921902, 9214294, 11112781, 11790741, 12354229, 12221282,16672620, 16403027; Product type e:enzyme

DNA sequence : 
GTGCTGACTGGATTTTCGCCATGGCCGGAAGAATGGGCTGACAAATACCGAAAAGACGGCTGCTGGAAGGGTGAGACGTT
CGGAGGAATGTTGAAAGAGCGCGCGGCTTTATACGGAAATCAAACTGCCGTGACGTGTAAAGATGTACATTGGACCTACA
AAGAATTAGATGAAAGGGCAGATCGTTTAGCGGCGGGGCTGCATAAGCTCGGAATTCAAAAGGAAGACCGCGTTGTCGTT
CAGCTGCCGAATATCGCTGAGTTTTTTGAAGTGATTTTCGCGCTGTTCCGGCTGGGAGCGCTGCCCGTTTTCGCGCTGCC
TTCTCATAGAAGCAGTGAGATTACGTATTTCTGCGAGTTTGCAGAGGCGAAAGCATACATCATTCCTGATATGCATTCAG
GTTTTGATTACAGGGCGCTTGCCAGACAGGTGAAAGACAAACTTCCGGATTTGGCGCATGTCATTGTGGCCGGCGAAGCT
GAAGAGTTTCAAGAACTGAGCAGCCTGCATAGAGAGCCTGTTCAGCTGGAAGATATAAGCCCGGCGGAAGTCGCCTTTTT
ACAGCTTTCAGGAGGCAGTACGGGGCTGTCCAAGCTGATTCCGCGAACACACGACGATTACATATACAGTTTGCGCATCA
GTGCGGAAATATGCGGCTTGGATCATCACAGCGTTTATTTGGCCGCTCTGCCGACAGCGCATAATTATCCGCTCAGCTCG
CCAGGTGTGCTGGGAACTTTATATGCCGGGGGCCGGGTTGTTCTGTCACCGACGCCGAGTCCGGATGACTGCTTCCCGTT
AATTGAAAAAGAACGTGTCACGATTACAGCGCTCGTCCCGCCGCTTGCGATGGTGTGGATGGACGCATCCGGTTCGCGAA
GTGATGATTTATCAAGCCTTCAAGTGCTGCAGGTGGGAGGCGCCAAATTCAGTGCTGAGGCGGCCCGCCGCGTGAAGAGC
GCTTTCGGATGCACCCTTCAGCAGGTTTTCGGAATGGCGGAAGGATTGGTGAATTATACGAGACTGGATGATCCTGAAGA
GATCATTGTCAATACGCAAGGCAGACCGATGTCACCTTTTGATGAGGTAAGGGTTTTAGACGATGACGGGCGGGATGTCG
CCCCCGGTGAAGCGGGACATTTGTTTACACGCGGCCCTTACACGATTCGCGGATATTATAAAGCGCCTGAACATAATGAA
AGATCATTCACAGCCGACGGATTTTATCAGACCGGCGATATCGTCAAACTGACGGCGGACGGCTATATCATCGTCGAAGG
GCGTGCGAAAGATCAAATCAATCGGGGCGGTGAAAAAATAGCCGCTGAGGAGGTGGAAAATCACCTTCTTGCGCATCCTG
CCGTTCATGACGCGGCCATGGTTTCAATGCCGGACGATTTTCTCGGGGAGCGATCCTGTGTGTTCGTCATCCCGAAAGGA
GAAGCGCCGAAACCGGGAGAGCTGAAAGCATTTTTACGTGAGCGCGGATTAGCGGCATATAAAATCCCCGACCGGATTGA
ATTTATCGCTTCTTTCCCGAAAACCGGCGTCGGCAAGGTCAGTAAAAAGGATCTTCGCGAAACGATCGCCCAAAAAGTAA
AGCCGGCTGAAATCAAACAATCTTAA

Protein sequence : 
MLTGFSPWPEEWADKYRKDGCWKGETFGGMLKERAALYGNQTAVTCKDVHWTYKELDERADRLAAGLHKLGIQKEDRVVV
QLPNIAEFFEVIFALFRLGALPVFALPSHRSSEITYFCEFAEAKAYIIPDMHSGFDYRALARQVKDKLPDLAHVIVAGEA
EEFQELSSLHREPVQLEDISPAEVAFLQLSGGSTGLSKLIPRTHDDYIYSLRISAEICGLDHHSVYLAALPTAHNYPLSS
PGVLGTLYAGGRVVLSPTPSPDDCFPLIEKERVTITALVPPLAMVWMDASGSRSDDLSSLQVLQVGGAKFSAEAARRVKS
AFGCTLQQVFGMAEGLVNYTRLDDPEEIIVNTQGRPMSPFDEVRVLDDDGRDVAPGEAGHLFTRGPYTIRGYYKAPEHNE
RSFTADGFYQTGDIVKLTADGYIIVEGRAKDQINRGGEKIAAEEVENHLLAHPAVHDAAMVSMPDDFLGERSCVFVIPKG
EAPKPGELKAFLRERGLAAYKIPDRIEFIASFPKTGVGKVSKKDLRETIAQKVKPAEIKQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-119 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-119 50
ybtE CAA21394.1 - Virulence HPI Protein 1e-119 50
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-119 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 9e-120 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-119 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-119 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-119 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-119 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE YP_008422235.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 4e-143 55
dhbE YP_008422235.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 2e-117 47
dhbE YP_008422235.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-113 44