Gene Information

Name : M493_16695 (M493_16695)
Accession : REF_PRJNA208285:M493
Strain : Geobacillus sp. JF8
Genome accession: NC_022080
Putative virulence/resistance : Resistance
Product : arsenate reductase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3106638 - 3107057 bp
Length : 420 bp
Strand : -
Note : catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence : 
CTCGCCGTGTTCCGCCGCGTCCGCGATGAAATTGGCGCGCGCATCCGCCGGTTTGCCGAGACGGGTGAATAGGCGCAAAG
CGGACAGAGACGAACGAAACCAAACGACGCTGCGGGTGAAAAGCCCAAACGCCCGGCAGCTGGAGCGATGCGGGCCAACG
TTCCTGACTCGTTGGCAACATGCCGCTCTAGCGGCTAGGGAAACCGCTGCACACAAAGAAGGTTCCAACCAGCCTTATGC
GGCTCAAGTTGGAACCTTTTTTGCTTATCGCTGATCGGCCGGGAACACGATGCCCGTTTGTCTTCGCGCTTCGTCCATGA
TTTCGATCGTCCAAAGCGAATGGCGGTGCGAGTTGATCGCTGATTCGCGCGCCCCGCTTTCAATGAGATCGATGAATTCG
TTCACTTCATAGTACATCGG

Protein sequence : 
MKKKVIYFLCTGNSCRSQMAEGWAKQLLGEEWEVYSAGLEAHGLNPNAVKVMKEVGIDISNQTSDVIDPDLLHRADLVVT
LCGHAADHCPVTPPHVKRVHWGFDDPAKAEGTEEEKLAVFRRVRDEIGARIRRFAETGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsC YP_252016.1 arsenate reductase Not tested SCCmec Protein 2e-41 65
arsC YP_005754064.1 arsenate reductase Not tested Type-XI SCCmec Protein 2e-39 63
arsC YP_252023.1 arsenate reductase Not tested SCCmec Protein 2e-39 62

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
M493_16695 REF_PRJNA208285:M493 arsenate reductase BAC0581 Protein 6e-52 82
M493_16695 REF_PRJNA208285:M493 arsenate reductase BAC0032 Protein 2e-39 64
M493_16695 REF_PRJNA208285:M493 arsenate reductase BAC0580 Protein 3e-38 62
M493_16695 REF_PRJNA208285:M493 arsenate reductase BAC0586 Protein 1e-14 42