Gene Information

Name : M493_16565 (M493_16565)
Accession : REF_PRJNA208285:M493
Strain : Geobacillus sp. JF8
Genome accession: NC_022080
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3078393 - 3079913 bp
Length : 1521 bp
Strand : +
Note : catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
TCCTACAGCGCGCTCCTTCTCTTTAACCGGATCGCCACCGATTTTTTGCTTCAGTTTGTCCGGGAAGAAAATGAATCGGC
CGCCCGCGCGTTTTTCGCCGCCGATCCGAACGAACTGATCGAAGTGTTCCACCATCTTTGCAGCGTCTATGCGAGCCGCT
GGCTTGAAGGACTGGAAGTCGACTAATGCCCCGCCCTGCTCCGGCAGCAGGGCGGTCCGTCTTCCGGTAGTTGACGCTTT
TTCGTTTGACAATATTGTCCAGCCATGCTACCCTAATCATCGGGAGGAATTTTCTAAATATTCCCCCAATGTAAGCGAAT
ACAAAATCAATTGAAGGAGGAATCGGGGATGATCTACGCACAACCAGGCCAGCCAGGCGCGCTTGTCACGTTCAAAACGC
GCTACGAAAACTTCATTGGCGGCAAATGGGTGCCGCCGGTCGACGGCGAATATTTTGAAAACATTACGCCGATCACCGGA
AAACCGTATTGCGAAGTGCCGCGCTCGAAAGCGGCGGACATCGAGCTGGCGCTTGACGCCGCCCATGCGGCCAAAGAGGC
ATGGGGGCGCACGTCTCCGGCCGAGCGCGCCCGTTTGCTGAACAAAATCGCCGACCGGATGGAAGAAAACTTGGAAATGC
TCGCGGTCGCGGAGACGTGGGAAAACGGCAAGCCGATCCGCGAAACGCTGGCGGCTGACATTCCGCTCGCCATCGACCAT
TTCCGCTATTTCGCCAGCTGCATCCGCGCACAAGAAGGCGCGATTTCCGAAATCGACCATAACACCGTTGCTTATCACTT
CAAAGAACCGCTCGGCGTCGTCGGGCAAATCATCCCGTGGAACTTCCCGATTCTCATGGCGGCGTGGAAACTCGCCCCGG
CATTGGCCGCAGGCAACTGCGTCGTCTTGAAACCGGCGGAACAAACGCCGACATCGATCCTCGTCCTCATCGAACTCATC
GAAGATTTGCTTCCACCTGGTGTCGTCAACATCGTGAACGGCTTTGGCTTAGAAGCCGGAAAACCGCTCGCCTCGAACCC
GCGCGTGGCGAAAGTGGCGTTCACCGGCGAAACGACGACCGGACGCCTCATCATGCAATACGCTTCACAAAACATTGTGC
CGGTCACATTGGAACTTGGCGGCAAGTCCCCGAACATTTTCTTCGCTGATGTCATGGACAAAGATGACGAGTTTCTCGAT
AAAGCGCTTGAAGGGTTTACAATGTTCGCTTTAAACCAAGGCGAAGTGTGCACATGCCCGTCGCGCGCCCTCATTCACGA
GTCGATTTACGACGCCTTTATGGAGCGGGCGCTTGAGCGCGTCAAGCAAATTAAACAAGGAAACCCGCTCGACACCGAAA
CGATGATCGGGGCGCAAGCGTCATCAGAACAACTGGAGAAAATCTTGTCGTACATCGACATCGGGAAGCAAGAAGGCGCT
GAACTTTTGATCGGCGGCGAGCGGAACATGCTCGAAGGAGAACTTTCCGGCGGCTATTACGTCAAGCCGACGATCTTCAA
A

Protein sequence :
MIYAQPGQPGALVTFKTRYENFIGGKWVPPVDGEYFENITPITGKPYCEVPRSKAADIELALDAAHAAKEAWGRTSPAER
ARLLNKIADRMEENLEMLAVAETWENGKPIRETLAADIPLAIDHFRYFASCIRAQEGAISEIDHNTVAYHFKEPLGVVGQ
IIPWNFPILMAAWKLAPALAAGNCVVLKPAEQTPTSILVLIELIEDLLPPGVVNIVNGFGLEAGKPLASNPRVAKVAFTG
ETTTGRLIMQYASQNIVPVTLELGGKSPNIFFADVMDKDDEFLDKALEGFTMFALNQGEVCTCPSRALIHESIYDAFMER
ALERVKQIKQGNPLDTETMIGAQASSEQLEKILSYIDIGKQEGAELLIGGERNMLEGELSGGYYVKPTIFKGHNKMRIFQ
EEIFGPVLAVTTFKDQDEALSIANETLYGLGAGVWTRDMNTAYRFGRGIQAGRVWTNCYHVYPAHAAFGGYKMSGIGRET
HKMMLDHYQQTKNLLVSYSPKKLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-139 66
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-147 65
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-147 65
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-147 65
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-147 65
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-62 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
M493_16565 REF_PRJNA208285:M493 aldehyde dehydrogenase VFG0082 Protein 1e-139 66