Gene Information

Name : M493_10305 (M493_10305)
Accession : REF_PRJNA208285:M493
Strain : Geobacillus sp. JF8
Genome accession: NC_022080
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1941295 - 1942776 bp
Length : 1482 bp
Strand : -
Note : Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
TACGCAGCCGCGGCGATTACGCTGCAAGGGGATACGAACCAAGTCCCGAACGGGTTTTTCAACTATACGGTCAAAGAGCC
GGTCGGCGTCTGCGGCCAAATCATCCCGTGGAACTATCCGCTGATGATGGCCGCTTGGAAGGTGGCGCCAGCCTTGGCGG
CAGGGTGTACGGTTGTGTTAAAGCCAGCAAGTTATACGCCGATCACGGCTTATATGCTGGCGGAAATTTGCCATGAGGCC
GGAGTGCCGGAGGGCGTCGTCAATGTGATTACGGGAAGCGGTTCCGAGATCGGGCCGTATATGACCGAACACCCGGGCAT
TGATAAAGTGGCGTTCACCGGGGAGACGGAAACGGGCAAAGACATTATGCGGCGCGCTTCGGGGACGTTGAAACGGGTAA
CGCTGGAATTAGGTGGGAAATCGCCGAACATCGTGTTTGACGACTGCGACATAGAAGCAGCGGTCAACGGTTCGCTTTAC
GGTATTTTTTACAATACCGGACAGTCGTGTGAAGCCCGCTCGCGGCTATTTGTACACGAAGCGATTTACGATGAATTCAT
GGAAAAATTTATCGAAAAGGCTTCCCGCGTCCGCGTCGGCAACCCGTTTGAAAAAGGGGTACATATGGGGGCGGTCATTT
CGCGAAGCCACCAACAAGTGATCGACGGCTATGTGAAGCTGGCGGTGGAGGAGGGTGGCGAAGTTTTGTACGGCGGAAAA
ATTCCGGAAGGCGAAGAGTTCGCGAAAGGCTACTGGTATATGCCGACGGTAATCGGCAATGTCAAAAATGAAATGCGGGT
GGCACAGGAAGAGATTTTCGGGCCGGTCGTTGTCGTGATGAAATTCCGCGATGAGGAAGAAGTTATCCGGCAGGCGAACG
ATACGATTTTTGGGTTAGGATCGGCCGTATGGACGAAAGACCACGGAAAAGCCCATCGTGTTGCTTCACGCATCCGGGCC
GGGATCGTCATGGTCAACTCGCCAATTTCCGCCTTCCCGGGCACGCCGTTTGGCGGGTACAAACAGTCAGGATTTGGCCG
TGAGCTGGCGCTTGAAACATTGAATTTGTACACTGAGACGAAAAGCGTCGTCTCGTATATCGGCAGCAAGCCGTTGAATT
TATTCGGGATTTAAAGTTCATTCCTATAAAACAATAATGACGATTTGGAGGGATTAAGATGGCGAATGCTGTAACAGTGG
AGAAACAATATTTAACGGTGGTTAAAGAAGAGGGGATTGCAGAAATCCACTTGCACATCAACAAATCAAACTCGTACGAC
TTGGAGTTTTATAAAGAGTTCAACGCAGCGATCGATGACATCCGCTTCGATCCGGACATCAAAGTCGTCATTCTCATGAG
CGATGTGCCGAAGTTTTTCTCGGCTGGGGCGGACATCAACTTTTTGCGGTCGGCCGACCCGCGGTTCAAAACGCAATTTT
GCCTGTTCTGCAACGAGACGCTTGATAAGATCGCCCGCTCGC

Protein sequence :
MKIKKHYPLFINGQYVESSNGEVFETVNPATEEVIATVAKATKEDVDRAVEAARAAFESGKWPKMTAAKRARLLNQIANL
MRERFDDLVYAEVLNSGKTVDAAKGQIMQAIEDFEFYAAAAITLQGDTNQVPNGFFNYTVKEPVGVCGQIIPWNYPLMMA
AWKVAPALAAGCTVVLKPASYTPITAYMLAEICHEAGVPEGVVNVITGSGSEIGPYMTEHPGIDKVAFTGETETGKDIMR
RASGTLKRVTLELGGKSPNIVFDDCDIEAAVNGSLYGIFYNTGQSCEARSRLFVHEAIYDEFMEKFIEKASRVRVGNPFE
KGVHMGAVISRSHQQVIDGYVKLAVEEGGEVLYGGKIPEGEEFAKGYWYMPTVIGNVKNEMRVAQEEIFGPVVVVMKFRD
EEEVIRQANDTIFGLGSAVWTKDHGKAHRVASRIRAGIVMVNSPISAFPGTPFGGYKQSGFGRELALETLNLYTETKSVV
SYIGSKPLNLFGI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 2e-83 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-81 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-83 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-83 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-83 41
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 9e-67 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-83 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
M493_10305 REF_PRJNA208285:M493 betaine-aldehyde dehydrogenase VFG0082 Protein 2e-81 41