Gene Information

Name : M493_00295 (M493_00295)
Accession : REF_PRJNA208285:M493
Strain : Geobacillus sp. JF8
Genome accession: NC_022080
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.11
Position : 22629 - 23903 bp
Length : 1275 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction met

DNA sequence :
ATGTTGGATGTGAAAGTGTTGCGCACTCAATTTCAGGAAGTGAAAGAAAAGTTGATGCAGCGCGGCGGGGATTTGGCCAA
CATCGACCGGTTTGAGCAGCTCGACAGAGAACGCCGCCGTTTGATCGCTGAGGCGGAAGAACTAAAAAGCAAACGCAATG
ATGTGTCGCAGCAAATCGCGGCTCTAAAGCGCGAAAAAAAGGACGCTGAATCGTTGATCACCGAAATGCGTGAGGTCGGT
GACCGCATTAAGCAAATGGACGAGCACATTCGCCAACTGGAAGAAGAACTCAACGCCCTGTTGTTATCGATTCCAAATAT
TCCGCATGAATCAGTGCCGGTCGGCCAGTCGGAAGAGGACAATGTCGAGGTGCGGAGATGGGGGGAGCCCCCTTCCTTTT
CCTTCGAACCGAAGCCGCATTGGGATATCGCCGACCAACTCGGTTTGCTCGATTTTGAGCGGGCGGCTAAAGTGACGGGA
AGCCGGTTTGTGTTTTACAAAGGACTGGGAGCGCGTCTTGAGCGGGCGTTAATCAACTTTATGCTCGACGTCCATCTTGA
TGAGTTTGGCTATCAAGAGGTGTTGCCGCCATATATAGTGAATCGGGCGAGCATGACCGGAACGGGGCAGCTGCCGAAAT
TTGCGGAGGACGTGTTCCACTTGGATAGTGAAGACTATTTTCTCATTCCGACAGCGGAAGTGCCGGTGACGAACTTGCAT
CGTGACGAAATTTTAACGGCCGACGACTTGCCGCTTTACTATGCGGCGTACAGCGCCTGCTTCCGCGCCGAGGCCGGTTC
GGCCGGCCGCGACACGAGAGGGCTCATCCGTCAGCACCAATTCAATAAAGTTGAGCTCGTCAAGTTCGTAAAACCGGAGC
ATTCATATGACGAGTTGGAAAAATTGACGCGCCAGGCAGAAACGATTTTGCAGCGGCTGGGGCTCCCGTATCGCGTTGTC
TCCTTATGCACGGGAGACCTTGGATTTTCCGCGGCGAAGACGTATGATATTGAGGTGTGGCTGCCAAGCTATGGCACATA
CCGGGAAATTTCGTCTTGCAGCAATTTTGAGGCGTTCCAGGCGCGCCGCGCCAATATCCGCTTCCGCCGCGAGCCGAAAG
CAAAACCAGAATATGTGCATACGCTAAATGGCTCGGGATTGGCCATTGGACGCACTGTTGCCGCCATTTTGGAAAACTAC
CAACAAGAAGACGGATCGGTCGTGATCCCAGAGGCGCTCCGCCCATACATGGGCAACCGGGACGTCATCCGTTAA

Protein sequence :
MLDVKVLRTQFQEVKEKLMQRGGDLANIDRFEQLDRERRRLIAEAEELKSKRNDVSQQIAALKREKKDAESLITEMREVG
DRIKQMDEHIRQLEEELNALLLSIPNIPHESVPVGQSEEDNVEVRRWGEPPSFSFEPKPHWDIADQLGLLDFERAAKVTG
SRFVFYKGLGARLERALINFMLDVHLDEFGYQEVLPPYIVNRASMTGTGQLPKFAEDVFHLDSEDYFLIPTAEVPVTNLH
RDEILTADDLPLYYAAYSACFRAEAGSAGRDTRGLIRQHQFNKVELVKFVKPEHSYDELEKLTRQAETILQRLGLPYRVV
SLCTGDLGFSAAKTYDIEVWLPSYGTYREISSCSNFEAFQARRANIRFRREPKAKPEYVHTLNGSGLAIGRTVAAILENY
QQEDGSVVIPEALRPYMGNRDVIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-128 62