Gene Information

Name : M493_09175 (M493_09175)
Accession : REF_PRJNA208285:M493
Strain : Geobacillus sp. JF8
Genome accession: NC_022080
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.1.1.45
Position : 1703079 - 1703873 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; Derived by automated computat

DNA sequence :
GATGAAATCAAGCGCAACCCGAACTCGCGCCGGCTGCTTGTCAGCGCCTGGAACGTGGCGGAATTGGATAAGATGAAGCT
GCCGCCGTGCCATTACGCTTTCCAGTTTTACGTCGCGAATGGACGGTTGTCATGCATGTGGCAGCAGCGCTCCGTTGACA
CGTTTTTAGGGCTGCCGTTTAACATTGCCAGCTATGCGCTTTTGACGCATATGATCGCCCAGCAGTGCGATTTGGACGTC
GGTGAACTGATTTTCACCGGCGGGGACGTCCATTTGTACAAAAATCATCTGGAACAAGCGAAACTGCAGCTGACGCGCGA
GCCGCGCCCGCTGCCAAAGCTCGTCATGAAACGGAAGCCACCGTCCATTTTTGACTATGAATACGACGATTTTGAAATCG
TCGGCTACGACCCGCATCCGGCGATTAAAGCGCCGGTGGCGGTGTGAAGGGGAGGATGCGATGATTTCGCACATTGTAGC
GATGGACGAAAACCGGGTGATCGGCAAGGACAACCGTTTGCCGTGGCATTTGCCGGCCGATTTGGCGTATTTTAAACGGG
TGACAATGGGACATGCCATCGTGATGGGGCGGAAGACGTTTGAGGCGATCGGCCGTCCGCTTCCCGGCCGGGAAAATATC
GTCGTGACACGCAACCGCTCGTTTCGCCCGGAAGGCTGTCTTACGCTTCACTCGCTTGATGACGTGAAACAGTGGGCCGC
CAGCCGCGGCGACAAAGAAGTGTTCATTATCGGCGGGGCCGAACTGTTTCAGGCGACGCTGCCGCTTGCCAGCCG

Protein sequence :
MRQYLQLLEDILENGVEKEDRTGVGTLSVFGRQLRFDLQDGFPLVTTKKLHIRSIVYELLWFLKGDTNVRYLQENGVTIW
DEWADENGDLGPIYGAQWRSWKGADGKTVDQIASVVDEIKRNPNSRRLLVSAWNVAELDKMKLPPCHYAFQFYVANGRLS
CMWQQRSVDTFLGLPFNIASYALLTHMIAQQCDLDVGELIFTGGDVHLYKNHLEQAKLQLTREPRPLPKLVMKRKPPSIF
DYEYDDFEIVGYDPHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-81 62