Gene Information

Name : M493_00740 (M493_00740)
Accession : REF_PRJNA208285:M493
Strain : Geobacillus sp. JF8
Genome accession: NC_022080
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 97395 - 99830 bp
Length : 2436 bp
Strand : +
Note : Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
ATGATGTTTGGCAGATTTACGGAACGGGCACAAAAAGTGCTGGCGTTGGCACAGGAAGAAGCCATTCGCCTCGGCCATAA
CAATATTGGCACGGAACACATTTTGCTCGGGCTGATCCGCGAAGGCGAAGGGATCGCCGCTAAAGCGCTTATGGCGCTCG
GGCTTGGCCCGGATAAAATTCAGAAAGAGGTCGAATCGCTCATCGGCCGCGGCAGTGAAGTGTCGCATACGATCCATTAC
ACACCGCGGGCGAAAAAAGTGATTGAGCTGTCGATGGATGAGGCGCGGAAGCTCGGTCATTCGTACGTCGGGACGGAACA
TATTTTGCTTGGATTGATCCGCGAGGGCGAAGGAGTAGCTGCCCGCGTGTTGAACAACTTAGGGGTGAGTTTGAACAAAG
CGCGCCAACAAGTGTTGCAGCTGCTCGGCAGCAATGAATCGGTATCAGGCCACGGTGGTGGAGGCGCCTCACATGTAAGC
ACACCGACGCTTGACAGCCTCGCCCGTGATTTGACGGCGATTGCCCGTGAAGGACGGCTTGATCCGGTCATCGGCCGCAG
CAAAGAAATTCAGCGCGTGATTGAAGTGTTGAGCCGGCGGACGAAAAACAATCCGGTGTTGATCGGTGAACCGGGTGTCG
GGAAAACCGCGATCGCCGAAGGATTGGCTCAGCAAATCGTCAATAATGAAGTACCGGAAACATTGCGTGATAAACGGGTC
ATGACGCTTGATATGGGTACGGTGGTCGCTGGGACGAAATACCGCGGCGAATTTGAAGACCGGCTGAAAAAAGTGATGGA
CGAAATTCGTCAGGCTGGCAATATCATTTTGTTCATCGATGAACTCCATACGTTAATCGGCGCCGGGGGGGCGGAAGGAG
CCATCGATGCGTCGAACATTTTAAAACCGGCCCTAGCGCGCGGAGAATTGCAATGTATCGGTGCGACAACGCTTGATGAA
TACCGGAAATACATCGAAAAAGATGCCGCGCTTGAACGCCGCTTCCAACCGATTCACGTGGATGAGCCGACGGTTGAGGA
GTCCATTCAAATTTTAAAAGGGTTGCGCGACCGATATGAGGCGCACCATCGCGTCTCGATCTCCGATGAGGCGATCATGC
AGGCAGTCAAACTGTCCGACCGTTACATTACCGACCGGTTCCTGCCGGATAAAGCGATCGACTTGATCGACGAAGCTTGC
TCAAAAGTGCGTCTCCGTTCGTTCACGGCGCCGCCGAAACTAAAAGAACTGGAGCAAAAGCTCGAAGAAGTGCGGAAAGA
AAAAGATGCAGCTGTCCAAAGCCAAGAGTTTGAAAAAGCGGCCTCGCTGCGCGATATGGAACAACGGCTGCGCGAAGAGC
TTGAGGAAACGAAACGGGCATGGAAAGAAAAGCAAGGTCAAGAAAACTCTGAAGTAACGGTCGAAGATATCGCCGCTGTT
GTCTCAAGTTGGACCGGCATTCCGGTATCTAAGCTGGCCGAAACGGAAACGGAGCGGCTGCTCAAGCTGGAGGAAATTTT
GCACGCGCGCGTCGTCGGTCAGGACGAGGCGGTTAAGGCAGTTGCTAAAGCGGTGCGCCGCGCCCGGGCTGGTTTGAAAG
ACCCGAAACGCCCGATCGGTTCGTTCATTTTCCTTGGTCCGACCGGCGTTGGGAAAACGGAATTGGCCCGTGCATTGGCC
GAGGCAATGTTTGGGGATGAAGACGCCCTCATCCGCATTGATATGTCCGAGTATATGGAGAAACACTCAACATCGCGGCT
CATCGGGTCGCCGCCAGGGTATGTCGGCTATGAAGAAGGCGGTCAGCTGACGGAAAAAGTGCGCCGGAAGCCATACTCGG
TCGTTCTGTTGGATGAAATGGAAAAAGCGCATCCTGACGTGTTTAATATTTTGCTGCAAGTATTAGAGGACGGGCGGTTG
ACCGACTCGAAAGGACGGACAGTCGACTTCCGCAACACGATTATTATTATGACATCCAACGTCGGTGCGGACGCCTTGAA
GCGGAACAAGTACGTCGGCTTTAACATTCAAGATGGAAACCAGCAATATCAGGACATGAAAAGTAAGGTGATGGACGAAC
TGAAAAAAGCGTTCCGACCGGAGTTTTTGAACCGGATCGACGAAATTATCGTCTTCCATTCGCTCGAAAAAGATCACCTA
AAACAAATTGTCCGCCTGATGGCCGATACGCTTGTGAAGCGGCTGAAGGAACAAAATATTGATCTTGAACTGACTGAGGC
AGCGATTGAGAAAATTGCCGCCGAAGGGTTTGATCCGGAATATGGGGCCCGCCCATTGCGCCGCGCCTTGCAAAAACATA
TCGAAGACCGTTTGTCTGAGGAGCTATTAAAAGGCACGATCGCCAAAGGGCAAAAAGTTGTTGTCGATGTGAAAGACGGA
GAGTTTGTCGTCTTGTCGAAACAGGCGGTCGTATAA

Protein sequence :
MMFGRFTERAQKVLALAQEEAIRLGHNNIGTEHILLGLIREGEGIAAKALMALGLGPDKIQKEVESLIGRGSEVSHTIHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNESVSGHGGGGASHVS
TPTLDSLARDLTAIAREGRLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPALARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPTVEESIQILKGLRDRYEAHHRVSISDEAIMQAVKLSDRYITDRFLPDKAIDLIDEAC
SKVRLRSFTAPPKLKELEQKLEEVRKEKDAAVQSQEFEKAASLRDMEQRLREELEETKRAWKEKQGQENSEVTVEDIAAV
VSSWTGIPVSKLAETETERLLKLEEILHARVVGQDEAVKAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
EAMFGDEDALIRIDMSEYMEKHSTSRLIGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEMEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIIIMTSNVGADALKRNKYVGFNIQDGNQQYQDMKSKVMDELKKAFRPEFLNRIDEIIVFHSLEKDHL
KQIVRLMADTLVKRLKEQNIDLELTEAAIEKIAAEGFDPEYGARPLRRALQKHIEDRLSEELLKGTIAKGQKVVVDVKDG
EFVVLSKQAVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 59
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-89 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
M493_00740 REF_PRJNA208285:M493 ATP-dependent Clp protease ATP-binding protein VFG0079 Protein 0.0 78
M493_00740 REF_PRJNA208285:M493 ATP-dependent Clp protease ATP-binding protein VFG0080 Protein 3e-141 54