Gene Information

Name : M493_05385 (M493_05385)
Accession : REF_PRJNA208285:M493
Strain : Geobacillus sp. JF8
Genome accession: NC_022080
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.8.1.4
Position : 958856 - 960268 bp
Length : 1413 bp
Strand : +
Note : E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
ATGGTAGTTGGCGATTTTGCAATTGAAACGGAAACGCTCGTCGTCGGTGCCGGTCCTGGCGGTTATGTGGCCGCCATCCG
CGCCGCACAGCTCGGCCAAAAAGTGACGATTGTGGAAAAAGGGAACTTAGGCGGCGTTTGCTTAAACGTCGGCTGCATCC
CGTCAAAAGCACTGATCTCCGCAAGCCACCGCTATGAGCAGGCGAAGCATTCCGAAGAAATGGGCATTAAGGCGGAGAAC
GTCACTGTCGATTTTGCCAAAGTGCAAGAATGGAAAGCAAGCGTCGTGAAAAAATTAACGGGCGGCGTCGAAGGGCTGTT
AAAAGGAAACAAAGTGGAGATTGTCAAAGGGGAAGCGTATTTTGTCGACGCCAATACGGTGCGTGTCGTCAACGGCGACA
GCGCGCAGACGTATACGTTCAAAAACGCCATTATCGCCACTGGTTCGCGCCCGATTGAGCTGCCGAGTTTCAAGTTTTCC
GACCGTATTCTTGATTCGACCGGAGCGCTCAACCTTGGGGAAGTTCCGAAATCGCTTGTTGTCATCGGCGGTGGTTATAT
CGGCATCGAGCTTGGTACAGCCTACGCCAACTTCGGAACGAAAGTAACGATTTTGGAAGGGGCCGGTGAAATTTTGTCCG
GTTTTGAAAAACAAATGGCGGCCATCATTAAACGCCGCTTAAAGAAAAAAGGCGTTGACATCGTGACAAATGCGCTGGCA
AAAGGAGCCGAGGAGCGCGCGGATGGCGTCACGGTCACGTATGAAGCTAACGGCGAAACGAAAACGGTTGATGCTGACTA
CGTGTTAGTCACGGTCGGCCGCCGTCCGAACACGGACGAGCTCGGCCTTGAACAAGTCGGCATTAAAATGACGGACCGCG
GCTTGATTGAAGTGGACGAACAATGCCGCACAAGCGTGCCGAACATTTTCGCCATCGGTGACATCGTCCCAGGGCCGGCG
CTCGCCCACAAGGCGTCGTATGAAGGAAAAGTAGCGGCTGAAGCCATCGCCGGCCATCCGTCAGTCGTCGATTATGTCGC
CATTCCGGCGGTCGTGTTCTCCGATCCGGAGTGCGCTTCCGTTGGTTATTTTGAGCAGCAGGCAAAAGACGAAGGCATTG
ATGTGATCACGGCGAAGTTCCCGTTTGCCGCCAACGGCCGCGCCTTGGCGCTGAACGACACGGACGGCTTCCTGAAGCTT
GTCGTTCGCAAAGAAGACGGCGTCGTCATCGGAGCGCAAATCATCGGCCCGAGCGCATCCGATATGATCGCCGAACTAGG
ATTGGCCATTGAGGCTGGGATGACGGCGGAAGATATTGCCTTGACGATCCATGCGCATCCGACGCTTGGCGAAATCGCCA
TGGAAGCAGCCGAAGTGGCGCTCGGCACACCGATTCATATTATTACGAAGTAA

Protein sequence :
MVVGDFAIETETLVVGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGVCLNVGCIPSKALISASHRYEQAKHSEEMGIKAEN
VTVDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAYFVDANTVRVVNGDSAQTYTFKNAIIATGSRPIELPSFKFS
DRILDSTGALNLGEVPKSLVVIGGGYIGIELGTAYANFGTKVTILEGAGEILSGFEKQMAAIIKRRLKKKGVDIVTNALA
KGAEERADGVTVTYEANGETKTVDADYVLVTVGRRPNTDELGLEQVGIKMTDRGLIEVDEQCRTSVPNIFAIGDIVPGPA
LAHKASYEGKVAAEAIAGHPSVVDYVAIPAVVFSDPECASVGYFEQQAKDEGIDVITAKFPFAANGRALALNDTDGFLKL
VVRKEDGVVIGAQIIGPSASDMIAELGLAIEAGMTAEDIALTIHAHPTLGEIAMEAAEVALGTPIHIITK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 9e-114 51