Gene Information

Name : N559_5186 (N559_5186)
Accession : YP_008414967.1
Strain :
Genome accession: NC_022078
Putative virulence/resistance : Resistance
Product : aminoglycoside adenylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 71274 - 72053 bp
Length : 780 bp
Strand : +
Note : -

DNA sequence : 
GTGACCATCGAAATTTCGAACCAACTATCAGAGGTGCTAAGCGTCATTGAGCGCCATCTGGAATCAACGTTGCTGGCCGT
GCATTTGTACGGCTCCGCAGTGGATGGCGGCCTGAAGCCATACAGCGATATTGATTTGTTGGTTACTGTGGCCGTAAAGC
TTGATGAAACGACGCGGCGAGCATTGCTCAATGATCTTATGGAGGCTTCGGCTTTCCCTGGCGAGAGCGAGACGCTCCGC
GCTATAGAAGTCACCCTTGTCGTGCATGACGACATCATCCCGTGGCGTTATCCGGCTAAGCGCGAGCTGCAATTTGGAGA
ATGGCAGCGCAATGACATTCTTGCGGGTATCTTCGAGCCAGCCATGATCGACATTGATCTAGCTATCCTGCTTACAAAAG
CAAGAGAACATAGCGTTGCCTTGGTAGGTCCGGCAGCGGAGGAATTCTTTGACCCGGTTCCTGAACAGGATCTATTCGAG
GCGCTGAGGGAAACCTTGAAGCTATGGAACTCGCAGCCCGACTGGGCCGGCGATGAGCGAAATGTAGTGCTTACGTTGTC
CCGCATTTGGTACAGCGCAATAACCGGCAAAATCGCGCCGAAGGATGTCGCTGCCGACTGGGCAATAAAACGCCTACCTG
CCCAGTATCAGCCCGTCTTACTTGAAGCTAAGCAAGCTTATCTGGGACAAAAAGAAGATCACTTGGCCTCACGCGCAGAT
CACTTGGAAGAATTTATTCGCTTTGTGAAAGGCGAGATCATCAAGTCAGTTGGTAAATGA

Protein sequence : 
MTIEISNQLSEVLSVIERHLESTLLAVHLYGSAVDGGLKPYSDIDLLVTVAVKLDETTRRALLNDLMEASAFPGESETLR
AIEVTLVVHDDIIPWRYPAKRELQFGEWQRNDILAGIFEPAMIDIDLAILLTKAREHSVALVGPAAEEFFDPVPEQDLFE
ALRETLKLWNSQPDWAGDERNVVLTLSRIWYSAITGKIAPKDVAADWAIKRLPAQYQPVLLEAKQAYLGQKEDHLASRAD
HLEEFIRFVKGEIIKSVGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aadA2 AGF35027.1 AadA2 aminoglycoside adenylyltransferase Not tested SGI1 Protein 6e-117 99
aadA2 ACF06158.1 aminoglycoside 3''-adenyltransferase Not tested Tn5036-like Protein 7e-117 99
aadA2 AAK02046.1 streptomycin/spectinomycin resistance protein Not tested SGI1 Protein 6e-117 99
aadA25 YP_005176241.1 aminoglycoside 3''-O-adenyltransferase protein Not tested ICEPmu1 Protein 3e-111 95
aadA1 CAJ77048.1 Aminoglycoside adenylyltransferase Not tested AbaR1 Protein 2e-104 88
aadDA1 CAJ77087.1 Aminoglycoside 3-adenylyltransferase Not tested AbaR1 Protein 3e-104 87
aadA1 ACV89835.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR7 Protein 3e-104 87
aadA1 YP_005797133.1 aminoglycoside 3'-adenyltransferase Not tested AbaR4e Protein 4e-104 87
unnamed AFV53113.1 AadA1 aminoglycoside (3') adenyltransferase Not tested AbGRI2-1 Protein 3e-104 87
aadA1 YP_005797149.1 aminoglycoside 3'-adenyltransferase Not tested AbaR4e Protein 4e-104 87
aadA1 AGK36646.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR26 Protein 3e-104 87
aadA1 YP_006098376.1 aminoglycoside adenylyltransferase Not tested Tn2411 Protein 4e-104 87
aadA1 ACN81025.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR5 Protein 4e-104 87
aadA1 CAD92142.1 aminoglycoside adenyltransferase Not tested Not named Protein 5e-104 86
aadA1 ACY75515.1 aminoglycoside adenyltransferase Not tested Tn6060 Protein 5e-104 86
aadA1 AAL08435.1 streptomycin adenyltransferase AadA1 Not tested SRL Protein 5e-98 82
aadA7 AAT37846.1 aminoglycoside adenyltransferase Not tested Class I integron Protein 7e-90 73
aadA7 AGF35062.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 7e-90 73
aadA7 AGK06932.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 7e-90 73
aadA7 AGK06969.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 7e-90 73
aadA7 AGK07015.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 7e-90 73
aadA7 AGK07073.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 7e-90 73
aadA7 AAR21854.1 aminoglycoside (3'')(9) adenylyltransferase; AAD(3'')(9) Not tested SGI1 Protein 7e-90 73

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AF174129.3.gene3.p01 Protein 2e-117 99
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AF294653.1.gene3.p01 Protein 7e-117 99
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AF047479.2.orf1.gene Protein 1e-115 99
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase EU118119.1.orf1.gene Protein 4e-117 99
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AY263741.gene.p01 Protein 2e-115 99
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AJ704863.gene12.p01 Protein 9e-97 88
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase NC_010410.6003170.p0 Protein 1e-104 88
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AM932669.1.gene3.p01 Protein 7e-105 87
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AJ584652.2.gene7.p01 Protein 4e-103 87
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AY123251.gene3.p01 Protein 2e-104 87
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase NC_010410.6003168.p0 Protein 2e-104 87
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AF313471.1.gene3.p01 Protein 2e-104 87
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AY339625.2.gene17.p0 Protein 2e-104 87
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AJ628353.gene.p01 Protein 4e-79 87
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase Y18050.2.gene6.p01 Protein 3e-104 86
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase JN596991.2.gene3.p01 Protein 3e-104 86
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase FR748153.1.gene5.p01 Protein 3e-104 86
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase U37105.2.gene4.p01 Protein 6e-93 75
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase DQ865198.gene.p01 Protein 3e-70 56
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase AY139598.1.gene2.p01 Protein 4e-69 56
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase NC_010558.1.6275994. Protein 3e-70 56
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase NC_003198.gene.p01 Protein 9e-48 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
N559_5186 YP_008414967.1 aminoglycoside adenylyltransferase VFG1026 Protein 3e-98 82